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NCT06458023 · ClinicalTrials.gov registry record · NA
TOF Monitoring Using the TetraGraph in Patients Less Than 1 Year of Age
A NA study of Surgery, sponsored by Joseph D. Tobias.
- Active
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT06458023: Active NA study of Surgery, sponsored by Joseph D. Tobias.
NCT06458023 is a NA study of Surgery that is active but no longer recruiting, run by Joseph D. Tobias. The registered enrollment target is 50 participants, below the 52,851-participant average among 120 other Surgery trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06458023, a NA study of Surgery, is active but no longer recruiting, sponsored by Joseph D. Tobias.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary objective of this study is to evaluate the efficacy of train-of-four (TOF) monitoring using the TetraGraph Neuromuscular Transmission Monitor in pediatric patients less than 1 year of age and when feasible to compare it to standard TOF monitoring using a qualitative monitor.
Primary Outcome
The Train of Four ratio (TOFr) is a quantitative measure used in anesthesia to assess the depth of neuromuscular blockade and recovery, calculated by dividing the amplitude of the fourth twitch by the first twitch after four 2-Hz stimuli. A TOF ratio is the standard threshold for safe extubation and indicates sufficient recovery from nondepolarizing agents. A TOF ratio \>/= 90% is the standard threshold for safe extubation and indicates sufficient recovery from nondepolarizing agents.
Conditions Studied
Interventions
- DEVICE TetraGraph (TM) NMT Monitor
Study Locations (1)
Ohio
- Nationwide Children's Hospital - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2024-06-11 |
| Est. Completion | 2025-12-31 |
| Phase | NA |
What the registry record for NCT06458023 still lists
NCT06458023 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 52,851-participant average among 120 other Surgery trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Surgery appearing as the primary indexed condition, and to 1 intervention - of which TetraGraph (TM) NMT Monitor is the first listed.
NCT06458023 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT06458023 about?
NCT06458023 is a clinical study titled "TOF Monitoring Using the TetraGraph in Patients Less Than 1 Year of Age". The primary objective of this study is to evaluate the efficacy of train-of-four (TOF) monitoring using the TetraGraph Neuromuscular Transmission Monitor in pediatric patients less than 1 year of age and when feasible to compare it to standard TOF monitoring using a qualitative monitor.
What is the current status of trial NCT06458023?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2024-06-11. Estimated completion is 2025-12-31.
What conditions does trial NCT06458023 study?
This clinical trial studies the following conditions: Surgery.
What interventions are being tested in trial NCT06458023?
The interventions under investigation include: TetraGraph (TM) NMT Monitor (DEVICE).
Who is sponsoring clinical trial NCT06458023?
This trial is sponsored by Joseph D. Tobias, which has 21 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06458023 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06458023's enrollment target sits among peer trials
50 88th of 120 higher than 27 of 120 other Surgery trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Surgery trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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