Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stroke: early-phase trial registry
218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #9 of 28,963 conditions by registered trial count.
456 US clinical trials · 218 currently recruiting · #9 of 28,963 conditions by registered trial count
Stroke: 456 US clinical trials tracked, 218 recruiting.
Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.
Open enrollment, early-phase tilt
Stroke has 456 registered US clinical trials, 218 of them open to new participants right now, about 48% of the total.
- 218
- recruiting participants now
- 48%
- of trials open to enrollment
- 16
- in Phase 3-4 (later-stage)
- 27
- top sponsor: VA Office of Research and Development
Corpus placement: #9 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.
Key findings
What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.
-
Stroke is recruiting above its size-band peers.
218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Stroke trials is spread across many organizations.
VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.
-
Most Stroke trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.
-
Stroke research is mostly interventional.
385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
456 total, page 3 of 10
Effect of Neural Constraints on Movement in Stroke
Northwestern University
NCT06666673
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
Northwell Health
NCT04755699
Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia
University of Pennsylvania
NCT06968663
tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia
MetroHealth Medical Center
NCT05866003
EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke
VA Office of Research and Development
NCT05628324
Tracking a Tactile Signal Along the Nervous System
Virginia Polytechnic Institute and State University
NCT06231810
Hybrid Robot+FES Stroke Rehabilitation
University of Maryland, Baltimore
NCT04550728
Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function
Jorge Gonzalez-Martinez
NCT07056348
Music Listening for Mental Health Recovery After Stroke
New York University
NCT07127159
Self-Administered Gaming and Exercise at Home (SAGEH)
Johns Hopkins University
NCT05929027
Cerebellar Stimulation for Aphasia Rehabilitation
Johns Hopkins University
NCT05093673
TDCS to Improve Post-Stroke Cognitive Impairment
Johns Hopkins University
NCT05195398
Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control
Jorge Gonzalez-Martinez
NCT07056361
Non-invasive VNS in Stroke Recovery
The Methodist Hospital Research Institute
NCT06761404
Human-Machine System for the H2 Lower Limb Exoskeleton
University of Houston
NCT02114450
Mechanisms of Open and Hidden Placebo in Stroke Recovery
Spaulding Rehabilitation Hospital
NCT05832567
R01.Aim 2.Study 1: IsoReach
Shirley Ryan AbilityLab
NCT06656754
Robot Aided Rehabilitation - Multi-joint Evaluations
University of Maryland, Baltimore
NCT02359812
Imaging Post-Stroke Recovery: Using MEG to Evaluate Cognition
Johns Hopkins University
NCT04188522
Biomarkers of Reaction To HIIT Exercise
VA Office of Research and Development
NCT06059872
Passive Limb Movement Study
Medical College of Wisconsin
NCT05935670
Rehabilitation Strategies for Social Participation in Chronic Stroke Survivors
University of Pittsburgh
NCT06758505
Early Robotic Gait Training After Stroke
Baylor Research Institute
NCT06430632
Use of 4D-ICE in Conjunction With TEE for Left Atrial Appendage Closure
Kansas City Heart Rhythm Research Foundation
NCT06061757
Transcranial Alternating Current Stimulation (tACS) in Aphasia
Medical College of Wisconsin
NCT04375722
BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement
Massachusetts General Hospital
NCT07091851
Effects of Exoskeleton-Assisted Gait Training on Functional Rehabilitation Outcomes in Patients With Stroke
University of Oklahoma
NCT03980457
Characterization and Clinical Trial of a Variable Friction Shoe
Shirley Ryan AbilityLab
NCT06234124
Impaired Interlimb Coordination During Locomotion in Individuals With Chronic Stroke: Contributors and Effect on Walking Function
University of Illinois at Chicago
NCT07006818
Optical Coherence Tomography Angiography in Neurological Disease
University of Texas Southwestern Medical Center
NCT06797765
Dysphagia Study Using Novel Microphone Device
Emory University
NCT07251140
Substrates for Post-Stroke Arm Rehabilitation
Massachusetts General Hospital
NCT06998485
The Neuralert Stroke Monitor Pilot Trial
Neuralert Technologies
NCT06368193
Fueling Strong Hearts for a Strong South Carolina
Clemson University
NCT07140952
Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.
University of New Mexi
NCT04432883
At Home Wearable Sensors and Smartphone for Stroke Survivors With Upper Limb Motor Challenges.
Spaulding Rehabilitation Hospital
NCT06787729
Post-Stroke Aphasia TMS
Medical College of Wisconsin
NCT06974279
Improving Blood Pressure Control in Stroke Patients by Increasing Access to a Home Blood Pressure Monitor
Stanford University
NCT05730465
Responses to Backward Walking Training Post-Stroke
VA Office of Research and Development
NCT04928482
Strategy Training for Optimizing Attention for Individuals With Spatial Neglect
University of Pittsburgh
NCT07331896
Neuromodulation-Enhanced Use of RObotic BALANCE Training to Improve Balance Function in Individuals With Stroke
Kessler Foundation
NCT07113041
Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes
Thomas Jefferson University
NCT06632587
Wireless Nerve Stimulation Device To Enhance Recovery After Stroke
Baylor Research Institute
NCT04534556
Exercise Primed Stroke Rehabilitation
VA Office of Research and Development
NCT04877444
High vs Low-frequency of High-intensity Training in Chronic Stroke
Indiana University
NCT06612723
PCMS Task After Moderate-to-severe Stroke
University of Utah
NCT05736653
Identifying the Optimal Dynamic Ankle-Foot Orthosis Bending Stiffness for Individuals Post-Stroke
University of Delaware
NCT06304519
Accelerated rTMS vs. Sham for Stroke Apathy
Medical University of South Carolina
NCT07113067
Assessment of a Physio-neuro Platform (SynPhNe) for Home-based Retraining of Hand Function in Stroke Survivors
Spaulding Rehabilitation Hospital
NCT02896348
Blood Flow Regulation and Neuromuscular Function Post-Stroke
Medical College of Wisconsin
NCT06027294
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 35 |
| Phase 2 | 34 |
| Phase 3 | 7 |
| Phase 4 | 9 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
What is open for Stroke right now
218 recruiting of 456 indexed (48% open).
Phase mix: 16 late (III/IV) vs 69 early (I/II) (early-phase heavy).
Top sponsor: VA Office of Research and Development (27 trials), 9 others listed. 50 shown below, recruiting first. #9 of 28,963 conditions by registered trial count.
How open-enrollment share is computed
Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.
Frequently Asked Questions
How many clinical trials are there for Stroke?
PlainTrial tracks 456 US clinical trials for Stroke, of which 218 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Stroke?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.