Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stroke: early-phase trial registry
218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #9 of 28,707 conditions by registered trial count.
456 US clinical trials · 218 currently recruiting · #9 of 28,707 conditions by registered trial count
Stroke: 456 US clinical trials tracked, 218 recruiting.
Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.
Enrollment posture brief
Registry condition stroke
OPEN 218 | RECR 48% | LATE 16 | EARLY 69 | RANK #9 | SPON 27
Volume-matched condition peers
Nearest open-share peer: Breast Cancer Stage II (48% recruiting · 23 trials)
Stroke lists 218 open slots (48% of 456 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Stroke is recruiting above its size-band peers.
218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Stroke trials is spread across many organizations.
VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.
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Most Stroke trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.
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Stroke research is mostly interventional.
385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
456 total, page 3 of 10
Effect of Neural Constraints on Movement in Stroke
Northwestern University
NCT06666673
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
Northwell Health
NCT04755699
Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia
University of Pennsylvania
NCT06968663
tDCS + CCFES-mediated Functional Task Practice for Post-stroke Upper Extremity Hemiplegia
MetroHealth Medical Center
NCT05866003
EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke
VA Office of Research and Development
NCT05628324
Tracking a Tactile Signal Along the Nervous System
Virginia Polytechnic Institute and State University
NCT06231810
Hybrid Robot+FES Stroke Rehabilitation
University of Maryland, Baltimore
NCT04550728
Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function
Jorge Gonzalez-Martinez
NCT07056348
Music Listening for Mental Health Recovery After Stroke
New York University
NCT07127159
Self-Administered Gaming and Exercise at Home (SAGEH)
Johns Hopkins University
NCT05929027
Cerebellar Stimulation for Aphasia Rehabilitation
Johns Hopkins University
NCT05093673
TDCS to Improve Post-Stroke Cognitive Impairment
Johns Hopkins University
NCT05195398
Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control
Jorge Gonzalez-Martinez
NCT07056361
Non-invasive VNS in Stroke Recovery
The Methodist Hospital Research Institute
NCT06761404
Human-Machine System for the H2 Lower Limb Exoskeleton
University of Houston
NCT02114450
Mechanisms of Open and Hidden Placebo in Stroke Recovery
Spaulding Rehabilitation Hospital
NCT05832567
R01.Aim 2.Study 1: IsoReach
Shirley Ryan AbilityLab
NCT06656754
Robot Aided Rehabilitation - Multi-joint Evaluations
University of Maryland, Baltimore
NCT02359812
Imaging Post-Stroke Recovery: Using MEG to Evaluate Cognition
Johns Hopkins University
NCT04188522
Biomarkers of Reaction To HIIT Exercise
VA Office of Research and Development
NCT06059872
Passive Limb Movement Study
Medical College of Wisconsin
NCT05935670
Rehabilitation Strategies for Social Participation in Chronic Stroke Survivors
University of Pittsburgh
NCT06758505
Early Robotic Gait Training After Stroke
Baylor Research Institute
NCT06430632
Use of 4D-ICE in Conjunction With TEE for Left Atrial Appendage Closure
Kansas City Heart Rhythm Research Foundation
NCT06061757
Transcranial Alternating Current Stimulation (tACS) in Aphasia
Medical College of Wisconsin
NCT04375722
BRIDGE: Blood Pressure Reduction and Intervention Delivery Via Group Engagement
Massachusetts General Hospital
NCT07091851
Effects of Exoskeleton-Assisted Gait Training on Functional Rehabilitation Outcomes in Patients With Stroke
University of Oklahoma
NCT03980457
Characterization and Clinical Trial of a Variable Friction Shoe
Shirley Ryan AbilityLab
NCT06234124
Impaired Interlimb Coordination During Locomotion in Individuals With Chronic Stroke: Contributors and Effect on Walking Function
University of Illinois at Chicago
NCT07006818
Optical Coherence Tomography Angiography in Neurological Disease
University of Texas Southwestern Medical Center
NCT06797765
Dysphagia Study Using Novel Microphone Device
Emory University
NCT07251140
Substrates for Post-Stroke Arm Rehabilitation
Massachusetts General Hospital
NCT06998485
The Neuralert Stroke Monitor Pilot Trial
Neuralert Technologies
NCT06368193
Fueling Strong Hearts for a Strong South Carolina
Clemson University
NCT07140952
Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.
University of New Mexi
NCT04432883
At Home Wearable Sensors and Smartphone for Stroke Survivors With Upper Limb Motor Challenges.
Spaulding Rehabilitation Hospital
NCT06787729
Post-Stroke Aphasia TMS
Medical College of Wisconsin
NCT06974279
Improving Blood Pressure Control in Stroke Patients by Increasing Access to a Home Blood Pressure Monitor
Stanford University
NCT05730465
Responses to Backward Walking Training Post-Stroke
VA Office of Research and Development
NCT04928482
Strategy Training for Optimizing Attention for Individuals With Spatial Neglect
University of Pittsburgh
NCT07331896
Neuromodulation-Enhanced Use of RObotic BALANCE Training to Improve Balance Function in Individuals With Stroke
Kessler Foundation
NCT07113041
Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes
Thomas Jefferson University
NCT06632587
Wireless Nerve Stimulation Device To Enhance Recovery After Stroke
Baylor Research Institute
NCT04534556
Exercise Primed Stroke Rehabilitation
VA Office of Research and Development
NCT04877444
High vs Low-frequency of High-intensity Training in Chronic Stroke
Indiana University
NCT06612723
PCMS Task After Moderate-to-severe Stroke
University of Utah
NCT05736653
Identifying the Optimal Dynamic Ankle-Foot Orthosis Bending Stiffness for Individuals Post-Stroke
University of Delaware
NCT06304519
Accelerated rTMS vs. Sham for Stroke Apathy
Medical University of South Carolina
NCT07113067
Assessment of a Physio-neuro Platform (SynPhNe) for Home-based Retraining of Hand Function in Stroke Survivors
Spaulding Rehabilitation Hospital
NCT02896348
Blood Flow Regulation and Neuromuscular Function Post-Stroke
Medical College of Wisconsin
NCT06027294
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 35 |
| Phase 2 | 34 |
| Phase 3 | 7 |
| Phase 4 | 9 |
Top Sponsors
Named interventions
Most-linked intervention names on Stroke records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Stroke trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Stroke page
456 registered trials, 218 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 218 Stroke trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Stroke trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stroke condition card totals 456 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.