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NCT06998485 · ClinicalTrials.gov registry record · NA
Substrates for Post-Stroke Arm Rehabilitation
A NA study of Stroke and Stroke Rehabilitation, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT06998485 is a NA study of Stroke and Stroke Rehabilitation that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 50 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06998485, a NA study of Stroke and Stroke Rehabilitation, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Difficulty moving the arm is very common and a major cause of disability after stroke. Although rehabilitation therapies (i.e., occupational and physical therapy) are the most common treatments used to improve arm motor function, it remains unknown how therapy actually changes brain pathways after stroke. This project seeks to generate fundamental knowledge about brain pathways that allow people to move their arm after stroke and how these pathways change with rehabilitation; we expect this knowledge to translate to new therapies to reduce stroke-related disability. We plan to enroll N = 50 patients with moderate to severe difficulty moving their arm after ischemic or hemorrhage stroke during the subacute period (3 to 6 months post stroke) into either 30 hours over 6 weeks of Arm Basis Training (a protocolized form of occupational therapy targeting motor control) or usual care. We will perform kinematic motor assessments, neuroimaging, and neurophysiology before and after therapy in order to test the hypothesis that intensive, target training improves arm motor control and induces corresponding anatomical and physiological changes of associated brain pathways.
Conditions Studied
Interventions
- BEHAVIORAL Arm Basis Training
Study Locations (1)
Massachusetts
- Laboratory for Translational Neurorecovery, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2025-10-07 |
| Est. Completion | 2030-04-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06998485
The ClinicalTrials.gov registry entry for NCT06998485 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which Arm Basis Training is the first listed.
NCT06998485 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06998485 about?
NCT06998485 is a clinical study titled "Substrates for Post-Stroke Arm Rehabilitation". Difficulty moving the arm is very common and a major cause of disability after stroke. Although rehabilitation therapies (i.e., occupational and physical therapy) are the most common treatments used to improve arm motor function, it remains unknown how therapy actually changes brain pathways after s...
What is the current status of trial NCT06998485?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2025-10-07. Estimated completion is 2030-04-30.
What conditions does trial NCT06998485 study?
This clinical trial studies the following conditions: Stroke, Stroke Rehabilitation, Neurorecovery.
What interventions are being tested in trial NCT06998485?
The interventions under investigation include: Arm Basis Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT06998485?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06998485 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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