Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stroke: early-phase trial registry
218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #9 of 28,707 conditions by registered trial count.
456 US clinical trials · 218 currently recruiting · #9 of 28,707 conditions by registered trial count
Stroke: 456 US clinical trials tracked, 218 recruiting.
Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.
Enrollment posture brief
Registry condition stroke
OPEN 218 | RECR 48% | LATE 16 | EARLY 69 | RANK #9 | SPON 27
Volume-matched condition peers
Nearest open-share peer: Breast Cancer Stage II (48% recruiting · 23 trials)
Stroke lists 218 open slots (48% of 456 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Stroke is recruiting above its size-band peers.
218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Stroke trials is spread across many organizations.
VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.
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Most Stroke trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.
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Stroke research is mostly interventional.
385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
456 total, page 2 of 10
Robotic Rehabilitation of the Upper Limb in Subacute Stroke
IRCCS San Raffaele Roma
NCT06839482
Alternative Therapies for Improving Physical Function in Individuals With Stroke
University of Illinois at Chicago
NCT03869138
Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease
Purdue University
NCT06638944
Virtual Reality Augmented Gait Adaptation in Stroke Survivors
University of Nebraska
NCT03787693
tACS to Enhance Language Abilities
University of Pennsylvania
NCT06092814
Motor rECovery witH eArly imagiNg In STroke
Northwestern University
NCT04165616
Achieving Meaningful Clinical Benchmarks With Ekso Gait Training During Acute Stroke Inpatient Rehabilitation.
Sunnyview Rehabilitation Hospital
NCT05241457
Transcranial Alternating Current Stimulation (tACS) for the Recovery of Phonological Short-Term Memory in Patients With Aphasia After Stroke
Medical College of Wisconsin
NCT06048159
Ischemic Conditioning Improves Walking Function Post Stroke
Medical College of Wisconsin
NCT04038697
Locomotor Function Following Transcutaneous Electrical Spinal Cord Stimulation in Individuals With Hemiplegic Stroke
Shirley Ryan AbilityLab
NCT05167786
Influence of Brain Oscillation-Dependent TMS on Motor Function
National Institute of Neurological Disorders and Stroke (NINDS)
NCT03288220
Explore the Effects of Cortical Priming on Visuomotor Stepping Learning in Persons With Chronic Stroke
The University of Texas Medical Branch, Galveston
NCT06681207
Improving Participation After Stroke Self-Management-Rehabilitation
University of Missouri-Columbia
NCT06588647
Telerehabilitation for Aphasia (TERRA)
University of South Carolina
NCT04682223
Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke
University of Pittsburgh
NCT06458153
Driver Training After Stroke
VA Office of Research and Development
NCT06672107
Non-invasive BCI-controlled Assistive Devices
University of Texas at Austin
NCT05183152
Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal
University of Illinois at Chicago
NCT04477330
Variable Intensive Early Walking Post-Stroke - 2 (VIEWS-2)
Indiana University
NCT05727930
Weight Loss and ExeRcise
VA Office of Research and Development
NCT06322030
Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking
Medical University of South Carolina
NCT07050355
Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke
Northwestern University
NCT03401762
Efficacy of a Telehealth Delivered Group Lifestyle Balance for People Post Stroke (tGLB-CVA)
Baylor Research Institute
NCT06569121
Neuroplasticity Biomarkers in Aphasia
University of Wisconsin, Madison
NCT06471127
Reactive Balance Training for Fall Prevention
University of Illinois at Chicago
NCT04205279
Studying Rehabilitation Treatments Using Video to Improve Recovery for Adults With Physical Disabilities
Ohio State University
NCT07092293
A Novel Wrist Wearable Sensor System to Promote Hemiparetic Upper Extremity Use in Subacute Stroke Survivors
Spaulding Rehabilitation Hospital
NCT06797154
Escitalopram and Language Intervention for Subacute Aphasia
Johns Hopkins University
NCT03843463
Personalized Transcranial Direct Current Stimulation in Stroke Recovery
The Methodist Hospital Research Institute
NCT06286800
Exercise and Motor Learning After Stroke (Study #3)
University of Delaware
NCT03726047
tDCS for Post-Stroke Cognitive Impairment
University of Oklahoma
NCT06516588
Emotional Recovery Post-Stroke
Medical University of South Carolina
NCT06782321
Brain Connections for Arm Movement After Stroke
VA Office of Research and Development
NCT04286516
Physical Capacity Building for Chronic Stroke
Medical University of South Carolina
NCT07039305
Deconstructing Post Stroke Hemiparesis
Providence VA Medical Center
NCT05993221
Improving Independent Multi-joint Arm Control After Stroke
University of Houston
NCT06523335
Model-informed Patient-specific Rehabilitation Using Robotics and Neuromuscular Modeling
University of Delaware
NCT06008743
Robot Aided Rehabilitation - Intervention
University of Maryland, Baltimore
NCT02359253
To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors
University of Kansas Medical Center
NCT06247553
rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke
The Cleveland Clinic
NCT03870672
Combining MyoCI With Memory Reactivation to Improve Motor Recovery After Stroke
Northwestern University
NCT04312269
Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits
Kessler Foundation
NCT06213272
K01 Impacts of Lingual Endurance Exercise
University of Cincinnati
NCT06072924
Producing Increasingly Complex Themes Using Right-hemisphere Engagement (PICTURE) Implemented With Telemedicine
Johns Hopkins University
NCT05845047
A Digital Intervention for Post-Stroke Depression and Executive Dysfunction
Weill Medical College of Cornell University
NCT05507138
Facilitating Neuroplastic Changes of Acute Stroke Survivors
University of Maryland, Baltimore
NCT06404268
Myofascial Dysfunction in Post Stroke Shoulder Pain
Johns Hopkins University
NCT06718413
I-Score: Intensive Stroke Cycling for Optimal Recovery and Economic Value
The Cleveland Clinic
NCT06585943
Spatial-Motor Stroke-Rehab Study
Emory University
NCT06053320
Cognition and Motor Learning Post-stroke
University of Southern California
NCT04829071
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 35 |
| Phase 2 | 34 |
| Phase 3 | 7 |
| Phase 4 | 9 |
Top Sponsors
Named interventions
Most-linked intervention names on Stroke records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Stroke trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Stroke page
456 registered trials, 218 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 218 Stroke trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Stroke trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stroke condition card totals 456 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.