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NCT07113067 · ClinicalTrials.gov registry record · Phase 1

Accelerated rTMS vs. Sham for Stroke Apathy

A Phase 1 study of Stroke and Motivation, sponsored by Medical University of South Carolina.

Recruiting
Registry status
Phase 1
Development phase
40
Enrollment target
1
Study location

NCT07113067 is a Phase 1 study of Stroke and Motivation that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 40 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07113067, a Phase 1 study of Stroke and Motivation, is actively recruiting participants, sponsored by Medical University of South Carolina.

RECRUITING
Registry status
Phase 1
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

Apathy is a common set of symptoms seen in many people following a stroke. Apathy occurs when a person has lost motivation, becomes withdrawn, and stops doing things that used to be important to them. Apathy has a large negative impact on a person's quality of life, and can also have a large impact the people who take care of them. There are currently no FDA-approved treatments to help with apathy, and other services like therapy may be difficult to access for people who have had a stroke. To address this problem, investigators are conducting a study to find out if a form of treatment called repetitive transcranial magnetic stimulation (rTMS) can be safe and helpful for people struggling with apathy after a stroke. This study will apply a new form of rTMS which can be delivered quickly to a part of the brain called the medial prefrontal cortex (mPFC). This study will help establish whether this treatment is safe, comfortable, and effective for people with apathy after a stroke, and will help researchers develop new forms of treatment.

Interventions

  • DEVICE MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System (Active)
  • DEVICE MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System (Sham)
  • OTHER Brainsight Neuronavigation System

Study Locations (1)

South Carolina

  • Medical University of South Carolina Brain Stimulation Lab - Charleston

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2025-08-08
Est. Completion 2027-06-30
Phase Phase 1

What the Registry Record Tells You About NCT07113067

The ClinicalTrials.gov registry entry for NCT07113067 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.

The record links to 7 conditions, with Stroke appearing as the primary indexed condition, and to 3 interventions - of which MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System (Active) is the first listed.

NCT07113067 reports 1 study location spanning 1 distinct geographic area - top geographies include South Carolina.

Frequently Asked Questions

What is clinical trial NCT07113067 about?

NCT07113067 is a clinical study titled "Accelerated rTMS vs. Sham for Stroke Apathy". Apathy is a common set of symptoms seen in many people following a stroke. Apathy occurs when a person has lost motivation, becomes withdrawn, and stops doing things that used to be important to them. Apathy has a large negative impact on a person's quality of life, and can also have a large impact ...

What is the current status of trial NCT07113067?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2025-08-08. Estimated completion is 2027-06-30.

What conditions does trial NCT07113067 study?

This clinical trial studies the following conditions: Stroke, Motivation, Stroke Sequelae, Apathy, Stroke/Brain Attack.

What interventions are being tested in trial NCT07113067?

The interventions under investigation include: MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System (Active) (DEVICE), MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System (Sham) (DEVICE), Brainsight Neuronavigation System (OTHER).

Who is sponsoring clinical trial NCT07113067?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07113067 being conducted?

This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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