Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 218 recruiting now early-phase tilt #9 of 28,963 conditions

Stroke: early-phase trial registry

218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #9 of 28,963 conditions by registered trial count.

456 US clinical trials · 218 currently recruiting · #9 of 28,963 conditions by registered trial count

Stroke: 456 US clinical trials tracked, 218 recruiting.

Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.

Open enrollment, early-phase tilt

Stroke has 456 registered US clinical trials, 218 of them open to new participants right now, about 48% of the total.

218
recruiting participants now
48%
of trials open to enrollment
16
in Phase 3-4 (later-stage)
27
top sponsor: VA Office of Research and Development

Corpus placement: #9 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Stroke is recruiting above its size-band peers.

    218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Stroke trials is spread across many organizations.

    VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.

  3. Most Stroke trials plan to enrol fewer than 100 people.

    Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.

  4. Stroke research is mostly interventional.

    385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 135Phase 234Phase 37Phase 49

Open and recent trials

456 total, page 4 of 10

RECRUITING NA 38 participants

Strategy Training for Individuals With Unilateral Neglect

University of Pittsburgh

NCT06400147

RECRUITING NA 37 participants

Real-time Personalized Brain State-dependent TMS After Stroke

Sara Hussain

NCT06533176

RECRUITING NA 36 participants

Finger Movement Training After Stroke

North Carolina State University

NCT05621980

RECRUITING Early Phase 1 36 participants

Multisensory Augmentation for Post-stroke Standing Balance

VA Office of Research and Development

NCT05760885

RECRUITING NA 36 participants

Constraint Induced Movement Therapy for Walking in Individuals Post Stroke

Shirley Ryan AbilityLab

NCT03264261

RECRUITING NA 32 participants

Behavioral and Neural Correlates of Post-Stroke Fatigue

Texas Woman's University

NCT06088914

RECRUITING Phase 2 32 participants

Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors

Spaulding Rehabilitation Hospital

NCT05626894

RECRUITING NA 32 participants

Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke

Northwestern University

NCT06598150

RECRUITING Phase 2 32 participants

Adaptive Trial Scheduling in Naming Treatment for Aphasia

University of Pittsburgh

NCT05653466

RECRUITING NA 30 participants

Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia

City University of New York

NCT04142866

RECRUITING NA 30 participants

Safety and Feasibility of an ExoNET for Supination Assistance for Stroke Survivors

Shirley Ryan AbilityLab

NCT06655636

RECRUITING Phase 2 30 participants

Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia

University of Pittsburgh

NCT05653440

RECRUITING NA 30 participants

Optimizing Gait Symmetry After Stroke Using Mechanical Constraints and Sensory Feedback

The University of Texas Medical Branch, Galveston

NCT07087769

RECRUITING NA 30 participants

Visual Plasticity Following Brain Lesions

Georgetown University

NCT07105358

RECRUITING NA 30 participants

Use of Sensory Substitution to Improve Arm Control After Stroke

Marquette University

NCT03298243

RECRUITING NA 30 participants

Virtual Reality-Integrated Propulsion Feedback for Stroke Rehab

The University of Texas Medical Branch, Galveston

NCT07087743

RECRUITING Early Phase 1 30 participants

Assistance Delivery and Muscle Coordination

The Catholic University of America

NCT07011173

RECRUITING NA 30 participants

Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke Upper Limb Motor Impairments

Carle Foundation Hospital

NCT05479006

RECRUITING Phase 2 30 participants

MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes

Medical College of Wisconsin

NCT06930638

RECRUITING NA 30 participants

User-friendliness of a Portable Driving Simulator

University of Kansas Medical Center

NCT03969927

RECRUITING NA 30 participants

Effect of Neuro20 Functional Electrical Stimulation Suit on Autonomic Function, Muscle Performance, and Gait

Brooks Rehabilitation

NCT07164846

RECRUITING NA 28 participants

Neurofeedback Intervention for Reading Deficits in Subacute Stroke

Kessler Foundation

NCT04875936

RECRUITING NA 26 participants

The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.

Duke University

NCT06765642

RECRUITING NA 25 participants

RESPARK - Brain Q for Chronic Stroke

University of Florida

NCT07095920

RECRUITING NA 25 participants

Community Stroke Self-management Program

University of Alabama, Tuscaloo

NCT06251128

RECRUITING NA 25 participants

MyHand 2: An Active Hand Orthosis for Stroke Patients

Columbia University

NCT04436042

RECRUITING NA 25 participants

Tracking Post-stroke Walking Improvements From the Clinic Into the Home

Western University of Health Sciences

NCT05454007

RECRUITING NA 25 participants

Q Therapeutic System for Chronic Stroke Recovery

Burke Rehabilitation Hospital

NCT06979466

RECRUITING Phase 1 24 participants

Vibrotactile Stimulation for Upper-Extremity Stroke Rehabilitation

University of Colorado, Denver

NCT06244719

RECRUITING NA 24 participants

Cultural Modification of an Evidence Based Healthy Lifestyle Intervention for People Post Stroke Who Identify as Hispanic/Latino

Baylor Research Institute

NCT06517459

RECRUITING Phase 2 24 participants

Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

University of Pennsylvania

NCT06842745

RECRUITING NA 24 participants

Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization

Duke University

NCT07220005

RECRUITING NA 24 participants

Improving Visual Field Deficits With Noninvasive Brain Stimulation

Beth Israel Deaconess Medical Center

NCT05085210

RECRUITING NA 21 participants

Exoskeleton for Balance

Medical University of South Carolina

NCT07356011

RECRUITING NA 20 participants

Modulation of Brain Rhythms in Stroke

University of North Carolina, Chapel Hill

NCT07121582

RECRUITING Phase 4 20 participants

Xeomin® and Gait Related Mobility After Stroke

Wake Forest University Health Sciences

NCT04908423

RECRUITING NA 20 participants

Spinal Cord Stimulation Combined With Physical Therapy in Post-Stroke Upper-Limb Motor Hemiparesis

Marco Capogrosso

NCT07153536

RECRUITING NA 20 participants

WIM Exosuit Wearable Soft Robot for Enhancing Walking Activity

Shirley Ryan AbilityLab

NCT07061691

RECRUITING NA 20 participants

FOA on Sit to Stand in Individuals Post Chronic Stroke

Western Carolina University

NCT07460804

RECRUITING Phase 1 20 participants

Identifying Personalized Brain States Predicting Residual Corticospinal Tract Output After Stroke

University of Texas at Austin

NCT06365099

RECRUITING NA 20 participants

Cycle and Stroke With Biofeedback for Power Symmetry

University of Utah

NCT06857916

RECRUITING NA 20 participants

Error-enhanced Learning & Recovery in 2 & 3 Dimensions

Shirley Ryan AbilityLab

NCT05180786

RECRUITING NA 20 participants

Spinal Stimulation and Mobility Devices

University of Washington

NCT05520359

RECRUITING Phase 1 20 participants

Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability

Johns Hopkins University

NCT07053917

RECRUITING NA 20 participants

Comparing Prism Adaptation Training With and Without TENS to Minimize Unilateral Spatial Neglect

Kettering Health Network

NCT07157865

RECRUITING NA 17 participants

Improving Measurement and Treatment of Post-stroke Neglect

VA Office of Research and Development

NCT03317860

RECRUITING NA 15 participants

Hand Exoskeleton Training Study

Medstar Health Research Institute

NCT06786858

RECRUITING 15 participants

Reliability and Validity of the PReFS

Baylor University

NCT07280923

RECRUITING NA 15 participants

Constraint-Induced Movement Therapy Plus Sensory Components After Stroke

University of Alabama at Birmingham

NCT05515237

RECRUITING NA 15 participants

Ankle Exoskeleton for Stroke Gait Enhancement

Georgia Institute of Technology

NCT07179627

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Phase Distribution

PhaseTrial count
Phase 1 35
Phase 2 34
Phase 3 7
Phase 4 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Stroke right now

218 recruiting of 456 indexed (48% open).

Phase mix: 16 late (III/IV) vs 69 early (I/II) (early-phase heavy).

Top sponsor: VA Office of Research and Development (27 trials), 9 others listed. 50 shown below, recruiting first. #9 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Stroke?

PlainTrial tracks 456 US clinical trials for Stroke, of which 218 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Stroke?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.