Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stroke: early-phase trial registry
218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #9 of 28,707 conditions by registered trial count.
456 US clinical trials · 218 currently recruiting · #9 of 28,707 conditions by registered trial count
Stroke: 456 US clinical trials tracked, 218 recruiting.
Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.
Enrollment posture brief
Registry condition stroke
OPEN 218 | RECR 48% | LATE 16 | EARLY 69 | RANK #9 | SPON 27
Volume-matched condition peers
Nearest open-share peer: Breast Cancer Stage II (48% recruiting · 23 trials)
Stroke lists 218 open slots (48% of 456 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Stroke is recruiting above its size-band peers.
218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Stroke trials is spread across many organizations.
VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.
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Most Stroke trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.
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Stroke research is mostly interventional.
385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
456 total, page 4 of 10
Strategy Training for Individuals With Unilateral Neglect
University of Pittsburgh
NCT06400147
Real-time Personalized Brain State-dependent TMS After Stroke
Sara Hussain
NCT06533176
Finger Movement Training After Stroke
North Carolina State University
NCT05621980
Multisensory Augmentation for Post-stroke Standing Balance
VA Office of Research and Development
NCT05760885
Constraint Induced Movement Therapy for Walking in Individuals Post Stroke
Shirley Ryan AbilityLab
NCT03264261
Behavioral and Neural Correlates of Post-Stroke Fatigue
Texas Woman's University
NCT06088914
Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors
Spaulding Rehabilitation Hospital
NCT05626894
Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke
Northwestern University
NCT06598150
Adaptive Trial Scheduling in Naming Treatment for Aphasia
University of Pittsburgh
NCT05653466
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
City University of New York
NCT04142866
Safety and Feasibility of an ExoNET for Supination Assistance for Stroke Survivors
Shirley Ryan AbilityLab
NCT06655636
Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia
University of Pittsburgh
NCT05653440
Optimizing Gait Symmetry After Stroke Using Mechanical Constraints and Sensory Feedback
The University of Texas Medical Branch, Galveston
NCT07087769
Visual Plasticity Following Brain Lesions
Georgetown University
NCT07105358
Use of Sensory Substitution to Improve Arm Control After Stroke
Marquette University
NCT03298243
Virtual Reality-Integrated Propulsion Feedback for Stroke Rehab
The University of Texas Medical Branch, Galveston
NCT07087743
Assistance Delivery and Muscle Coordination
The Catholic University of America
NCT07011173
Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke Upper Limb Motor Impairments
Carle Foundation Hospital
NCT05479006
MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes
Medical College of Wisconsin
NCT06930638
User-friendliness of a Portable Driving Simulator
University of Kansas Medical Center
NCT03969927
Effect of Neuro20 Functional Electrical Stimulation Suit on Autonomic Function, Muscle Performance, and Gait
Brooks Rehabilitation
NCT07164846
Neurofeedback Intervention for Reading Deficits in Subacute Stroke
Kessler Foundation
NCT04875936
The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.
Duke University
NCT06765642
RESPARK - Brain Q for Chronic Stroke
University of Florida
NCT07095920
Community Stroke Self-management Program
University of Alabama, Tuscaloo
NCT06251128
MyHand 2: An Active Hand Orthosis for Stroke Patients
Columbia University
NCT04436042
Tracking Post-stroke Walking Improvements From the Clinic Into the Home
Western University of Health Sciences
NCT05454007
Q Therapeutic System for Chronic Stroke Recovery
Burke Rehabilitation Hospital
NCT06979466
Vibrotactile Stimulation for Upper-Extremity Stroke Rehabilitation
University of Colorado, Denver
NCT06244719
Cultural Modification of an Evidence Based Healthy Lifestyle Intervention for People Post Stroke Who Identify as Hispanic/Latino
Baylor Research Institute
NCT06517459
Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia
University of Pennsylvania
NCT06842745
Low Intensity Focused Ultrasound Stimulation in Stroke Patients - Parameter Optimization
Duke University
NCT07220005
Improving Visual Field Deficits With Noninvasive Brain Stimulation
Beth Israel Deaconess Medical Center
NCT05085210
Exoskeleton for Balance
Medical University of South Carolina
NCT07356011
Modulation of Brain Rhythms in Stroke
University of North Carolina, Chapel Hill
NCT07121582
Xeomin® and Gait Related Mobility After Stroke
Wake Forest University Health Sciences
NCT04908423
Spinal Cord Stimulation Combined With Physical Therapy in Post-Stroke Upper-Limb Motor Hemiparesis
Marco Capogrosso
NCT07153536
WIM Exosuit Wearable Soft Robot for Enhancing Walking Activity
Shirley Ryan AbilityLab
NCT07061691
FOA on Sit to Stand in Individuals Post Chronic Stroke
Western Carolina University
NCT07460804
Identifying Personalized Brain States Predicting Residual Corticospinal Tract Output After Stroke
University of Texas at Austin
NCT06365099
Cycle and Stroke With Biofeedback for Power Symmetry
University of Utah
NCT06857916
Error-enhanced Learning & Recovery in 2 & 3 Dimensions
Shirley Ryan AbilityLab
NCT05180786
Spinal Stimulation and Mobility Devices
University of Washington
NCT05520359
Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability
Johns Hopkins University
NCT07053917
Comparing Prism Adaptation Training With and Without TENS to Minimize Unilateral Spatial Neglect
Kettering Health Network
NCT07157865
Improving Measurement and Treatment of Post-stroke Neglect
VA Office of Research and Development
NCT03317860
Hand Exoskeleton Training Study
Medstar Health Research Institute
NCT06786858
Reliability and Validity of the PReFS
Baylor University
NCT07280923
Constraint-Induced Movement Therapy Plus Sensory Components After Stroke
University of Alabama at Birmingham
NCT05515237
Ankle Exoskeleton for Stroke Gait Enhancement
Georgia Institute of Technology
NCT07179627
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 35 |
| Phase 2 | 34 |
| Phase 3 | 7 |
| Phase 4 | 9 |
Top Sponsors
Named interventions
Most-linked intervention names on Stroke records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Stroke trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Stroke page
456 registered trials, 218 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 218 Stroke trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Stroke trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stroke condition card totals 456 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.