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NCT06666673 · ClinicalTrials.gov registry record · Early Phase 1
Effect of Neural Constraints on Movement in Stroke
A Early Phase 1 study of Stroke, sponsored by Northwestern University.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 64
- Enrollment target
- 1
- Study location
NCT06666673: Recruiting Early Phase 1 study of Stroke, sponsored by Northwestern University.
NCT06666673 is a Early Phase 1 study of Stroke that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 64 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06666673, a Early Phase 1 study of Stroke, is actively recruiting participants, sponsored by Northwestern University.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 64 participants
- Enrollment target
- 1
- Study location
Study Summary
This study investigates the effects of Tizanidine on the voluntary movement controls of the arms of participants who have had a stroke and have not had a stroke by measuring medication-induced changes in upper extremity kinematics, pupillometry, and brain activity. Tizanidine is approved by the U.S. Food and Drug Administration. Understanding how different areas of the brain are involved in movement impairments may help rehabilitation efforts and assist in restoring healthy movement in individuals who have had a stroke.
Primary Outcome
Brace height quantifies the amplification in motor unit discharge rate generated by PICs. Brace height is sensitive to the level of neuromodulatory drive received by motoneurons.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Tizanidine
Study Locations (1)
Illinois
- Northwestern University, Dept. of PTHMS 645 N Michigan Ave, Suite 1100 - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 64 participants |
| Start Date | 2024-08-23 |
| Est. Completion | 2029-07-31 |
| Phase | Early Phase 1 |
What NCT06666673 shows while recruiting
NCT06666673 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 64 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06666673 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT06666673 about?
NCT06666673 is a clinical study titled "Effect of Neural Constraints on Movement in Stroke". This study investigates the effects of Tizanidine on the voluntary movement controls of the arms of participants who have had a stroke and have not had a stroke by measuring medication-induced changes in upper extremity kinematics, pupillometry, and brain activity. Tizanidine is approved by the U.S....
What is the current status of trial NCT06666673?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 64 participants. The study started on 2024-08-23. Estimated completion is 2029-07-31.
What conditions does trial NCT06666673 study?
This clinical trial studies the following conditions: Stroke.
What interventions are being tested in trial NCT06666673?
The interventions under investigation include: Placebo (DRUG), Tizanidine (DRUG).
Who is sponsoring clinical trial NCT06666673?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06666673 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06666673's enrollment target sits among peer trials
64 198th of 454 higher than 255 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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