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NCT04550728 · ClinicalTrials.gov registry record · Phase 1
Hybrid Robot+FES Stroke Rehabilitation
A Phase 1 study of Stroke, sponsored by University of Maryland, Baltimore.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT04550728: Recruiting Phase 1 study of Stroke, sponsored by University of Maryland, Baltimore.
NCT04550728 is a Phase 1 study of Stroke that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 60 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04550728, a Phase 1 study of Stroke, is actively recruiting participants, sponsored by University of Maryland, Baltimore.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators have developed a novel robot-guided stretching under intelligent control and combine it with active movement training, which helped increase joint ROM, reduce spasticity and joint stiffness, increase muscle force output, and improve locomotion. However, for stroke survivors with sensorimotor impairment, their peripheral muscle may not sufficiently be recruited. Functional electrical stimulation (FES), has been shown its advantage to activate the peripheral muscles for people with neurological conditions. The investigators thus make a hybrid robot-FES rehabilitation system, combining the advantage of robot and FES technologies for stroke motor recovery. The investigators further would like to translate the technologies from lab to home-based training. Thus, the investigators will conduct a randomized, controlled, primarily home-based clinical trial using an ankle robot alone or combined with functional electrical stimulation (FES) to treat sensorimotor and locomotion impairments post-stroke.
Primary Outcome
The assessment is a measure of lower extremity (LE) motor and sensory impairments post-stroke.
Conditions Studied
Interventions
- COMBINATION_PRODUCT Ankle robot training group
- COMBINATION_PRODUCT Ankle robot training and functional electrical stimulation(FES) group
Study Locations (1)
Maryland
- University of Maryland School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-08-01 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 1 |
What NCT04550728 shows while recruiting
NCT04550728 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 2 interventions - of which Ankle robot training group is the first listed.
NCT04550728 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04550728 about?
NCT04550728 is a clinical study titled "Hybrid Robot+FES Stroke Rehabilitation". The investigators have developed a novel robot-guided stretching under intelligent control and combine it with active movement training, which helped increase joint ROM, reduce spasticity and joint stiffness, increase muscle force output, and improve locomotion. However, for stroke survivors with se...
What is the current status of trial NCT04550728?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2021-08-01. Estimated completion is 2026-12-31.
What conditions does trial NCT04550728 study?
This clinical trial studies the following conditions: Stroke.
What interventions are being tested in trial NCT04550728?
The interventions under investigation include: Ankle robot training group (COMBINATION_PRODUCT), Ankle robot training and functional electrical stimulation(FES) group (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT04550728?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04550728 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04550728's enrollment target sits among peer trials
60 206th of 454 higher than 236 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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