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NCT04188522 · ClinicalTrials.gov registry record
Imaging Post-Stroke Recovery: Using MEG to Evaluate Cognition
A clinical trial of Stroke and Stroke Sequelae, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- 55
- Enrollment target
- 1
- Study location
NCT04188522 is a study of Stroke and Stroke Sequelae that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 55 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04188522, a study of Stroke and Stroke Sequelae, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- 55 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a study using magnetoencephalography (MEG) to look at recovery in those with minor stroke. The investigators know that these individuals report difficulties in attention, concentration, multi-tasking, energy level, and processing speed that appear to be independent of lesion size or location. The underlying pathophysiology is unclear; however, anecdotally, many individuals are significantly improved by 6 months post-stroke. One hypothesis is that a single lesion, regardless of size, may disrupt the classic neural networks required for cognitive function. The investigators are currently collecting data to better characterize these difficulties and stroke patients' recovery as part of a previously approved recovery study. In this sub-study, the investigators propose to add MEG at 1 and 6 months in a subset of individuals with small: 1) subcortical, and 2) cortical lesions. The investigators will partner with colleagues at the University of Maryland (College Park), who are well experienced with MEG to conduct this research. In addition a control population of age-similar individuals will be recruited for comparison. Cerebral activation patterns of individuals with stroke versus controls will be compared, both across patients with stroke at a given time point, and within subjects from 1 to 6 months to determine the association of abnormal activation with cognitive dysfunction and recovery. \*\*The investigators have recently extended follow-up by adding an additional assessment at 12 months and will enroll additional participants (up to 40 patients with minor stroke, 15 age-similar controls).
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Magnetoencephalography (MEG)
Study Locations (1)
Maryland
- Johns Hopkins Bayview Medical Center - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 55 participants |
| Start Date | 2018-07-01 |
| Est. Completion | 2026-06-30 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04188522
The ClinicalTrials.gov registry entry for NCT04188522 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which Magnetoencephalography (MEG) is the first listed.
NCT04188522 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT04188522 about?
NCT04188522 is a clinical study titled "Imaging Post-Stroke Recovery: Using MEG to Evaluate Cognition". This is a study using magnetoencephalography (MEG) to look at recovery in those with minor stroke. The investigators know that these individuals report difficulties in attention, concentration, multi-tasking, energy level, and processing speed that appear to be independent of lesion size or location...
What is the current status of trial NCT04188522?
This trial is currently recruiting. The enrollment target is 55 participants. The study started on 2018-07-01. Estimated completion is 2026-06-30.
What conditions does trial NCT04188522 study?
This clinical trial studies the following conditions: Stroke, Stroke Sequelae, Stroke/Brain Attack.
What interventions are being tested in trial NCT04188522?
The interventions under investigation include: Magnetoencephalography (MEG) (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04188522?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04188522 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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