Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stress: early-phase trial registry
64 of 153 indexed Stress trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #73 of 28,707 conditions by registered trial count.
153 US clinical trials · 64 currently recruiting · #73 of 28,707 conditions by registered trial count
Stress: 153 US clinical trials tracked, 64 recruiting.
Stress is the subject of 153 registered US clinical trials on ClinicalTrials.gov, 64 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Virginia Commonwealth University, running 5 of these trials.
Enrollment posture brief
Registry condition stress
OPEN 64 | RECR 42% | LATE 2 | EARLY 12 | RANK #73 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Colorectal Neoplasms (42% recruiting · 55 trials)
Stress lists 64 open slots (42% of 153 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Stress on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Stress is recruiting above its size-band peers.
64 of 153 indexed trials (41.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Stress trials is spread across many organizations.
Virginia Commonwealth University accounts for 5 of 153 trials (3.3%). 113 distinct sponsors appear on at least one study for this condition label.
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Typical Stress enrolment sits around 80 participants.
Median target enrolment is 80 among the 153 trials that report a genuine target (sentinel values excluded). 86 of those (56.2%) plan for fewer than 100 participants.
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Stress research is mostly interventional.
142 interventional and 11 observational studies make up this index (92.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
153 total, page 2 of 4
Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High School Students
Milton S. Hershey Medical Center
NCT07240792
Feasibility of Virtual Tai Chi Easy for Registered Nurses
University of Arizona
NCT06423638
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
Mclean Hospital
NCT05837104
The Effect of Mindfulness on Vascular Inflammation in Stable Coronary Disease
Massachusetts General Hospital
NCT04505865
Intranasal Oxytocin Intervention for Caregivers to Persons With Dementia
University of Nebraska
NCT06364228
Surviving Daily Life
Thomas Jefferson University
NCT07054723
Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study
Massachusetts General Hospital
NCT04496947
Depression, Aging, Stress and Heart Health Study
University of North Carolina, Chapel Hill
NCT05570721
Effects of Body Composition on Vascular Health in Females with a Healthy Body Weight
Ball State University
NCT06818500
The Effects of Daily Polyvagal Exercises on Stress in Students of Physical Therapy
Dominican University New York
NCT06557083
ACT for HIV-Positive Men
University of Alabama at Birmingham
NCT06625437
Impact of OnabotulinumtoxinA (BOTOX®) on Stress
Center for Advanced Facial Plastic Surgery
NCT06778421
Influence of Melatonin on Cardiovascular and Thermoregulatory Responses to Stress
Baylor University
NCT07138443
Applied Clinical Neuroscience and Its Effect on Self-reported Stress and Other Physiological Markers
Dylan Saulsbery
NCT06358560
Caring for Vets and Service Members: Caring Contacts for Stressed and Distressed Veterans and Service Members
University of Washington
NCT06136234
Evaluating Stress Management Among Allogeneic HCT Caregivers
H. Lee Moffitt Cancer Center and Research Institute
NCT05078229
Wellbeing of the ECE Workforce in Low-resourced Locations
Colorado School of Public Health
NCT05416216
Stress Reduction After Use of a Haptic Vibrotactile Trigger Technology Patch: Analysis and Assessment
SuperPatch Limited
NCT06708715
Evaluating Stress Management Strategies Within the School Readiness Parenting Program
Florida International University
NCT06626750
This Study Explores the Mental Health Impact of Two Akashic Records Sessions.
Rasa Healing
NCT07219914
Effects of a Theanine for Stress Relief Formulation in Individuals Who Report Occasional Moderate High Levels of Stress.
Supplement Formulators
NCT05854017
Feasibility & Acceptability of App-based Cognitive Behavioral Therapy for Postpartum Depression Prevention
Women and Infants Hospital of Rhode Island
NCT06365645
Disrupted Connections: The Impact of Acute Stress on Memory Integration
Nevada State University
NCT07055555
Predictors of Cognitive Outcomes in Geriatric Depression
David Steffens
NCT05273996
The Feasibility of the Pray Until Something Happens (PUSH) Intervention-OUTPATIENT
University of Florida
NCT06580067
Effect of Black Cumin Seed Oil Supplementation on Cortisol, Stress and Mood
Shawn Talbott
NCT06950424
A Clinical Trial to Evaluate the Effects of a Herbal Tincture on Energy Levels, Weight Management, and Markers of Metabolic Health
Apothekary
NCT06949540
A Study on Prevalence, Protection and Recovery From COVID-19 in Seasoned Yoga Practitioners in Comparison to Age and Gender Matched Controls
Beth Israel Deaconess Medical Center
NCT04498442
Mental Health Pathways in Internet Support Groups
Carnegie Mellon University
NCT02396472
SSIs for Mental Health and Loneliness
University of California, Irvine
NCT05687162
Incentivizing Meditation App Habit Formation
Arizona State University
NCT05217602
Project SOLVE: Trial of a Brief Digital Problem-solving Intervention
Harvard University
NCT04806321
Parenting Young Children Study
University of Oregon
NCT05180487
Bundle Consent and Expectation Setting in Pediatric Intensive Care Unit
Virginia Commonwealth University
NCT04697173
Daily Assessment of Mood and Social Media Behaviors Study
Southern Methodist University
NCT04349423
Personal Relevance of Psychotherapy for Asian Americans
IRIS Media
NCT06632158
Stress Biomarkers:Attaching Biological Meaning to Field Friendly Salivary Measures
University of Michigan
NCT01673087
Intervention Trial to Reduce Mental Health Disparities in Latina Immigrant Women
University of Washington
NCT03545282
Personalized Trials for Stress Management Against Standard of Care
Northwell Health
NCT05408832
Coherence Training for Military Personnel
United States Naval Medical Center, San Diego
NCT01599598
Physiological Responses in Tobacco Chippers
Oregon Health and Science University
NCT01237834
A Study to Assess the Effects of Dietary Supplement Drinks on Sleep, Stress and Mood
The Water Street Collective
NCT06378567
Life Enhancing Activities for Family Caregivers
University of California, San Francisco
NCT01825681
Mindfulness Takes Practice
Arizona State University
NCT04378530
Strong People Strength Training Study
Cornell University
NCT04203563
Hostile Bias Modification Training (HBMT) Study
Walter Reed Army Institute of Research (WRAIR)
NCT04997356
Strategies for Responding to Stress
University of Texas at Austin
NCT03289156
Brain and Meditation (BAM) Study
University of Wisconsin, Madison
NCT05215314
Efficacy of the Tony Robbins Rapid Planning Method (RPM)
Applied Science & Performance Institute
NCT06539949
Web-based Patient Reported Outcome Measurement Information System (PROMIS ) to Explore Burden and Stress in Cancer Caregivers (BaSiC2)
National Institutes of Health Clinical Center (CC)
NCT01981538
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 6 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Stress records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Stress trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Stress page
153 registered trials, 64 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 64 Stress trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Virginia Commonwealth University sponsors the most Stress trials on record, review their full trial history before evaluating a specific study. See Virginia Commonwealth University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stress condition card totals 153 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.