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Stress clinical trials
64 of 153 indexed Stress trials are currently recruiting.
153 US clinical trials · 64 currently recruiting
Stress is the subject of 153 registered US clinical trials on ClinicalTrials.gov, 64 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Virginia Commonwealth University, running 5 of these trials.
The research picture
Stress has 153 registered US clinical trials, 64 of them open to new participants right now, about 42% of the total.
- 64
- recruiting participants now
- 42%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 5
- top sponsor: Virginia Commonwealth University
Active & Recent Trials
153 total, page 2 of 4
Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High School Students
Milton S. Hershey Medical Center
NCT07240792
Feasibility of Virtual Tai Chi Easy for Registered Nurses
University of Arizona
NCT06423638
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
Mclean Hospital
NCT05837104
The Effect of Mindfulness on Vascular Inflammation in Stable Coronary Disease
Massachusetts General Hospital
NCT04505865
Intranasal Oxytocin Intervention for Caregivers to Persons With Dementia
University of Nebraska
NCT06364228
Surviving Daily Life
Thomas Jefferson University
NCT07054723
Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study
Massachusetts General Hospital
NCT04496947
Depression, Aging, Stress and Heart Health Study
University of North Carolina, Chapel Hill
NCT05570721
Effects of Body Composition on Vascular Health in Females with a Healthy Body Weight
Ball State University
NCT06818500
The Effects of Daily Polyvagal Exercises on Stress in Students of Physical Therapy
Dominican University New York
NCT06557083
ACT for HIV-Positive Men
University of Alabama at Birmingham
NCT06625437
Impact of OnabotulinumtoxinA (BOTOX®) on Stress
Center for Advanced Facial Plastic Surgery
NCT06778421
Influence of Melatonin on Cardiovascular and Thermoregulatory Responses to Stress
Baylor University
NCT07138443
Applied Clinical Neuroscience and Its Effect on Self-reported Stress and Other Physiological Markers
Dylan Saulsbery
NCT06358560
Caring for Vets and Service Members: Caring Contacts for Stressed and Distressed Veterans and Service Members
University of Washington
NCT06136234
Evaluating Stress Management Among Allogeneic HCT Caregivers
H. Lee Moffitt Cancer Center and Research Institute
NCT05078229
Wellbeing of the ECE Workforce in Low-resourced Locations
Colorado School of Public Health
NCT05416216
Stress Reduction After Use of a Haptic Vibrotactile Trigger Technology Patch: Analysis and Assessment
SuperPatch Limited
NCT06708715
Evaluating Stress Management Strategies Within the School Readiness Parenting Program
Florida International University
NCT06626750
This Study Explores the Mental Health Impact of Two Akashic Records Sessions.
Rasa Healing
NCT07219914
Effects of a Theanine for Stress Relief Formulation in Individuals Who Report Occasional Moderate High Levels of Stress.
Supplement Formulators
NCT05854017
Feasibility & Acceptability of App-based Cognitive Behavioral Therapy for Postpartum Depression Prevention
Women and Infants Hospital of Rhode Island
NCT06365645
Disrupted Connections: The Impact of Acute Stress on Memory Integration
Nevada State University
NCT07055555
Predictors of Cognitive Outcomes in Geriatric Depression
David Steffens
NCT05273996
The Feasibility of the Pray Until Something Happens (PUSH) Intervention-OUTPATIENT
University of Florida
NCT06580067
Effect of Black Cumin Seed Oil Supplementation on Cortisol, Stress and Mood
Shawn Talbott
NCT06950424
A Clinical Trial to Evaluate the Effects of a Herbal Tincture on Energy Levels, Weight Management, and Markers of Metabolic Health
Apothekary
NCT06949540
A Study on Prevalence, Protection and Recovery From COVID-19 in Seasoned Yoga Practitioners in Comparison to Age and Gender Matched Controls
Beth Israel Deaconess Medical Center
NCT04498442
Mental Health Pathways in Internet Support Groups
Carnegie Mellon University
NCT02396472
SSIs for Mental Health and Loneliness
University of California, Irvine
NCT05687162
Incentivizing Meditation App Habit Formation
Arizona State University
NCT05217602
Project SOLVE: Trial of a Brief Digital Problem-solving Intervention
Harvard University
NCT04806321
Parenting Young Children Study
University of Oregon
NCT05180487
Bundle Consent and Expectation Setting in Pediatric Intensive Care Unit
Virginia Commonwealth University
NCT04697173
Daily Assessment of Mood and Social Media Behaviors Study
Southern Methodist University
NCT04349423
Personal Relevance of Psychotherapy for Asian Americans
IRIS Media
NCT06632158
Stress Biomarkers:Attaching Biological Meaning to Field Friendly Salivary Measures
University of Michigan
NCT01673087
Intervention Trial to Reduce Mental Health Disparities in Latina Immigrant Women
University of Washington
NCT03545282
Personalized Trials for Stress Management Against Standard of Care
Northwell Health
NCT05408832
Coherence Training for Military Personnel
United States Naval Medical Center, San Diego
NCT01599598
Physiological Responses in Tobacco Chippers
Oregon Health and Science University
NCT01237834
A Study to Assess the Effects of Dietary Supplement Drinks on Sleep, Stress and Mood
The Water Street Collective
NCT06378567
Life Enhancing Activities for Family Caregivers
University of California, San Francisco
NCT01825681
Mindfulness Takes Practice
Arizona State University
NCT04378530
Strong People Strength Training Study
Cornell University
NCT04203563
Hostile Bias Modification Training (HBMT) Study
Walter Reed Army Institute of Research (WRAIR)
NCT04997356
Strategies for Responding to Stress
University of Texas at Austin
NCT03289156
Brain and Meditation (BAM) Study
University of Wisconsin, Madison
NCT05215314
Efficacy of the Tony Robbins Rapid Planning Method (RPM)
Applied Science & Performance Institute
NCT06539949
Web-based Patient Reported Outcome Measurement Information System (PROMIS ) to Explore Burden and Stress in Cancer Caregivers (BaSiC2)
National Institutes of Health Clinical Center (CC)
NCT01981538
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 6 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Stress Trial Landscape
153 indexed Stress studies · 64 recruiting (42%).
Phase mix: 2 late (III/IV) vs 12 early (I/II).
Top sponsor: Virginia Commonwealth University (5 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Stress?
PlainTrial tracks 153 US clinical trials for Stress, of which 64 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Stress?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.