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Stress clinical trials
64 of 153 indexed Stress trials are currently recruiting.
153 US clinical trials · 64 currently recruiting
Stress is the subject of 153 registered US clinical trials on ClinicalTrials.gov, 64 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Virginia Commonwealth University, running 5 of these trials.
The research picture
Stress has 153 registered US clinical trials, 64 of them open to new participants right now, about 42% of the total.
- 64
- recruiting participants now
- 42%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 5
- top sponsor: Virginia Commonwealth University
Active & Recent Trials
153 total, page 3 of 4
Clinical Trial of a Supporter-Targeted Intervention to Improve Outcomes in Recent Sexual Assault Survivors
University of Washington
NCT05345405
Natural Modulators of Immune Function and Mood
3 Waves Wellness
NCT05508529
Chronic Alcohol and Brain Stress Circuit Response
Yale University
NCT01031264
A Study to Evaluate the Effect of SlimBiotics Probiotic Formula on Weight Management and Metabolic Health Outcomes
Slimbiotics
NCT05917314
Mindfulness Training in the Medical Health Care System
University of Miami
NCT06003699
Decreasing Stress and Improving Self-control With "Stress in Control" (Sync) Training
Yale University
NCT01721499
VSMART (Video-Conference Stress Management and Relaxation Training for Older Women With Breast Cancer)
University of Miami
NCT03955991
Breathing Interventions for Relaxation: Dosing Through Extended Exhale
Vanderbilt University Medical Center
NCT02870868
Evaluation Study of Talk Parenting Skills
Oregon Research Behavioral Intervention Strategies
NCT04633434
Building Resiliency Among Caregivers of Curvivors and Metavivors
Massachusetts General Hospital
NCT05702723
Brain Mechanisms of Emotion and Motivation: A Mind-Body Study
Mclean Hospital
NCT01850472
The Effect of Psychotherapy on Stress Biochemistry: An RCT of Psychotherapy and Emotional Freedom Techniques (EFT)
Soul Medicine Institute
NCT00641394
A Randomized-Controlled Trial to Investigate the Effect of a Novel Music Therapy Application to Reduce Anxiety and Stress
SoundMind
NCT06021821
Effect of an 8-week Heartfulness Meditation Program on Burnout and Stress at Veterinary Specialty Hospital
Heartfulness Institute
NCT06338098
Effectiveness of Music Practical Examinations
Russell Sage College
NCT06187272
Family Promoting Positive Emotions Pilot Study
Vanderbilt University
NCT05223842
Health Enhancement And Resilience Training
University of California, San Francisco
NCT01959126
Meditation for NICU Moms
St. Louis University
NCT03574766
Effects of Open-label Placebos on COVID-related Psychological Health
Michigan State University
NCT05035550
Mindfulness, Yoga, and Cardiovascular Disease
The Cleveland Clinic
NCT00696852
The Effect of Music-Based Mindfulness to Cope with Acculturative-Related Stress
University of Miami
NCT06166732
Mindfulness Practices for Healthcare Professional Trainees
Virginia Commonwealth University
NCT03403335
The Effects of Smell on Mood and Physical Responses
National Center for Complementary and Integrative Health (NCCIH)
NCT00097253
Internet and Telephone Support Intervention for Stroke Caregivers
VA Office of Research and Development
NCT04348851
Mindful Kala: Virtual Bharatanatyam Wellness Program for Students
Yale University
NCT04745364
Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity
University of California, San Francisco
NCT04606199
Neurophysiology, Estrogen, and Stress Exposure in the Emergence of Depression in Adolescent Girls
University of North Carolina, Chapel Hill
NCT03450135
Stress-reduction Wellness Program for Midlife Black Women (B-SWELL)
University of Cincinnati
NCT04404478
Seasonal Patterns of Stress, Diet and Physical Activity - Life in All Seasons (LENAS)
USDA Grand Forks Human Nutrition Research Center
NCT01674296
Stress Management Intervention in Women's Heart Clinic, Heart SMART Program
Mayo Clinic
NCT02670421
Ashwagandha Extract for Weight and Stress Management in Overweight and Obese Adults
SF Research Institute
NCT07215455
A Trauma-Informed Approach for Positive Youth Development for Montana Students
Montana State University
NCT04664855
The Feasibility of the PAINReportIt Guided Relaxation Intervention-INPATIENT
University of Florida
NCT02729350
Investigating the Detection of Bovine and Soy Proteins in Human Milk
University of Idaho
NCT04851340
Mindfulness-Music Intervention for Adolescents and Young Adults With Cancer
Dana-Farber Cancer Institute
NCT03709225
Mindfulness-Based Stress Reduction for Metro Nashville Public School Employees
Vanderbilt University Medical Center
NCT05051969
Study to Evaluate the Efficacy of Asystems' Complete Calm Supplementation on Sleep Quality and Duration, Anxiety, and Stress
Asystem
NCT05190640
Digital Interventions to Treat Hazardous Drinking
Yale University
NCT04890652
SmartManage Stress Management for HIV+ Cancer Survivors
University of Miami
NCT04544917
Project MiCRIM- Sleep and Stress Intervention
Florida State University
NCT05384067
A Mixed Methods Evaluation of HPI Resilience Intervention Study
Johnson & Johnson Health and Wellness Solutions
NCT03451240
Does Mindfulness Training Change the Processing of Social Threat?
Massachusetts General Hospital
NCT00992875
Stress Management and Resiliency Training (SMART) for Family Medicine Residents at Eglin AFB
Laura Rhaney
NCT03936114
Healthcare Providers as Trusted Messengers to Increase Receipt of Tax Credits Among Low-income Families
University of California, Los Angeles
NCT05612685
Virtual Reality Experience for Stress Reduction in Cardiology Patients
University of California, Los Angeles
NCT04984655
Art for Hearts/Black Women's Hearts Paint Night
Virginia Commonwealth University
NCT05252507
Parenting Young Children in Pediatrics
University of Oregon
NCT06273228
KickStart30: A 30-Day Intervention for Patients With Rheumatoid Arthritis (RA)
University of Texas at Austin
NCT03993548
Efficacy of Healing Touch in Stressed Neonates
National Center for Complementary and Integrative Health (NCCIH)
NCT00034008
First Responder Resiliency Program During COVID-19
Mayo Clinic
NCT04536376
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 6 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Stress Trial Landscape
153 indexed Stress studies · 64 recruiting (42%).
Phase mix: 2 late (III/IV) vs 12 early (I/II).
Top sponsor: Virginia Commonwealth University (5 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Stress?
PlainTrial tracks 153 US clinical trials for Stress, of which 64 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Stress?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.