Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stress: early-phase trial registry
64 of 153 indexed Stress trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #73 of 28,707 conditions by registered trial count.
153 US clinical trials · 64 currently recruiting · #73 of 28,707 conditions by registered trial count
Stress: 153 US clinical trials tracked, 64 recruiting.
Stress is the subject of 153 registered US clinical trials on ClinicalTrials.gov, 64 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is Virginia Commonwealth University, running 5 of these trials.
Enrollment posture brief
Registry condition stress
OPEN 64 | RECR 42% | LATE 2 | EARLY 12 | RANK #73 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Colorectal Neoplasms (42% recruiting · 55 trials)
Stress lists 64 open slots (42% of 153 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Stress on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Stress is recruiting above its size-band peers.
64 of 153 indexed trials (41.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Stress trials is spread across many organizations.
Virginia Commonwealth University accounts for 5 of 153 trials (3.3%). 113 distinct sponsors appear on at least one study for this condition label.
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Typical Stress enrolment sits around 80 participants.
Median target enrolment is 80 among the 153 trials that report a genuine target (sentinel values excluded). 86 of those (56.2%) plan for fewer than 100 participants.
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Stress research is mostly interventional.
142 interventional and 11 observational studies make up this index (92.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
153 total, page 3 of 4
Clinical Trial of a Supporter-Targeted Intervention to Improve Outcomes in Recent Sexual Assault Survivors
University of Washington
NCT05345405
Natural Modulators of Immune Function and Mood
3 Waves Wellness
NCT05508529
Chronic Alcohol and Brain Stress Circuit Response
Yale University
NCT01031264
A Study to Evaluate the Effect of SlimBiotics Probiotic Formula on Weight Management and Metabolic Health Outcomes
Slimbiotics
NCT05917314
Mindfulness Training in the Medical Health Care System
University of Miami
NCT06003699
Decreasing Stress and Improving Self-control With "Stress in Control" (Sync) Training
Yale University
NCT01721499
VSMART (Video-Conference Stress Management and Relaxation Training for Older Women With Breast Cancer)
University of Miami
NCT03955991
Breathing Interventions for Relaxation: Dosing Through Extended Exhale
Vanderbilt University Medical Center
NCT02870868
Evaluation Study of Talk Parenting Skills
Oregon Research Behavioral Intervention Strategies
NCT04633434
Building Resiliency Among Caregivers of Curvivors and Metavivors
Massachusetts General Hospital
NCT05702723
Brain Mechanisms of Emotion and Motivation: A Mind-Body Study
Mclean Hospital
NCT01850472
The Effect of Psychotherapy on Stress Biochemistry: An RCT of Psychotherapy and Emotional Freedom Techniques (EFT)
Soul Medicine Institute
NCT00641394
A Randomized-Controlled Trial to Investigate the Effect of a Novel Music Therapy Application to Reduce Anxiety and Stress
SoundMind
NCT06021821
Effect of an 8-week Heartfulness Meditation Program on Burnout and Stress at Veterinary Specialty Hospital
Heartfulness Institute
NCT06338098
Effectiveness of Music Practical Examinations
Russell Sage College
NCT06187272
Family Promoting Positive Emotions Pilot Study
Vanderbilt University
NCT05223842
Health Enhancement And Resilience Training
University of California, San Francisco
NCT01959126
Meditation for NICU Moms
St. Louis University
NCT03574766
Effects of Open-label Placebos on COVID-related Psychological Health
Michigan State University
NCT05035550
Mindfulness, Yoga, and Cardiovascular Disease
The Cleveland Clinic
NCT00696852
The Effect of Music-Based Mindfulness to Cope with Acculturative-Related Stress
University of Miami
NCT06166732
Mindfulness Practices for Healthcare Professional Trainees
Virginia Commonwealth University
NCT03403335
The Effects of Smell on Mood and Physical Responses
National Center for Complementary and Integrative Health (NCCIH)
NCT00097253
Internet and Telephone Support Intervention for Stroke Caregivers
VA Office of Research and Development
NCT04348851
Mindful Kala: Virtual Bharatanatyam Wellness Program for Students
Yale University
NCT04745364
Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity
University of California, San Francisco
NCT04606199
Neurophysiology, Estrogen, and Stress Exposure in the Emergence of Depression in Adolescent Girls
University of North Carolina, Chapel Hill
NCT03450135
Stress-reduction Wellness Program for Midlife Black Women (B-SWELL)
University of Cincinnati
NCT04404478
Seasonal Patterns of Stress, Diet and Physical Activity - Life in All Seasons (LENAS)
USDA Grand Forks Human Nutrition Research Center
NCT01674296
Stress Management Intervention in Women's Heart Clinic, Heart SMART Program
Mayo Clinic
NCT02670421
Ashwagandha Extract for Weight and Stress Management in Overweight and Obese Adults
SF Research Institute
NCT07215455
A Trauma-Informed Approach for Positive Youth Development for Montana Students
Montana State University
NCT04664855
The Feasibility of the PAINReportIt Guided Relaxation Intervention-INPATIENT
University of Florida
NCT02729350
Investigating the Detection of Bovine and Soy Proteins in Human Milk
University of Idaho
NCT04851340
Mindfulness-Music Intervention for Adolescents and Young Adults With Cancer
Dana-Farber Cancer Institute
NCT03709225
Mindfulness-Based Stress Reduction for Metro Nashville Public School Employees
Vanderbilt University Medical Center
NCT05051969
Study to Evaluate the Efficacy of Asystems' Complete Calm Supplementation on Sleep Quality and Duration, Anxiety, and Stress
Asystem
NCT05190640
Digital Interventions to Treat Hazardous Drinking
Yale University
NCT04890652
SmartManage Stress Management for HIV+ Cancer Survivors
University of Miami
NCT04544917
Project MiCRIM- Sleep and Stress Intervention
Florida State University
NCT05384067
A Mixed Methods Evaluation of HPI Resilience Intervention Study
Johnson & Johnson Health and Wellness Solutions
NCT03451240
Does Mindfulness Training Change the Processing of Social Threat?
Massachusetts General Hospital
NCT00992875
Stress Management and Resiliency Training (SMART) for Family Medicine Residents at Eglin AFB
Laura Rhaney
NCT03936114
Healthcare Providers as Trusted Messengers to Increase Receipt of Tax Credits Among Low-income Families
University of California, Los Angeles
NCT05612685
Virtual Reality Experience for Stress Reduction in Cardiology Patients
University of California, Los Angeles
NCT04984655
Art for Hearts/Black Women's Hearts Paint Night
Virginia Commonwealth University
NCT05252507
Parenting Young Children in Pediatrics
University of Oregon
NCT06273228
KickStart30: A 30-Day Intervention for Patients With Rheumatoid Arthritis (RA)
University of Texas at Austin
NCT03993548
Efficacy of Healing Touch in Stressed Neonates
National Center for Complementary and Integrative Health (NCCIH)
NCT00034008
First Responder Resiliency Program During COVID-19
Mayo Clinic
NCT04536376
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 6 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Stress records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Stress trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Stress page
153 registered trials, 64 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 64 Stress trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Virginia Commonwealth University sponsors the most Stress trials on record, review their full trial history before evaluating a specific study. See Virginia Commonwealth University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stress condition card totals 153 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.