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NCT07138443 · ClinicalTrials.gov registry record · NA
Influence of Melatonin on Cardiovascular and Thermoregulatory Responses to Stress
A NA study of Stress and Mental Stress, sponsored by Baylor University.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT07138443: Recruiting NA study of Stress and Mental Stress, sponsored by Baylor University.
NCT07138443 is a NA study of Stress and Mental Stress that is actively recruiting participants, run by Baylor University. The registered enrollment target is 20 participants, below the 786-participant average among 152 other Stress trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07138443, a NA study of Stress and Mental Stress, is actively recruiting participants, sponsored by Baylor University.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to evaluate the influence of acute oral melatonin supplementation on cardiovascular and skin temperature responses to mental stress. The hypothesis is that acute melatonin will lead to reduced cardiovascular and skin temperature responsiveness to acute mental stress.
Primary Outcome
Heart rate will be continuously monitored using electrocardiogram during a 10-minute baseline and in response to the Trier Social Stress Test. Heart rate reactivity during the stress will be quantified.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Melatonin 3 MG Oral Tablet
- DIETARY_SUPPLEMENT Placebo Oral Tablet
Study Locations (1)
Texas
- Baylor University Autonomic Function Laboratory - Waco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-08 |
| Est. Completion | 2026-08 |
| Phase | NA |
What NCT07138443 shows while recruiting
NCT07138443 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 786-participant average among 152 other Stress trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Stress appearing as the primary indexed condition, and to 2 interventions - of which Melatonin 3 MG Oral Tablet is the first listed.
NCT07138443 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT07138443 about?
NCT07138443 is a clinical study titled "Influence of Melatonin on Cardiovascular and Thermoregulatory Responses to Stress". This study aims to evaluate the influence of acute oral melatonin supplementation on cardiovascular and skin temperature responses to mental stress. The hypothesis is that acute melatonin will lead to reduced cardiovascular and skin temperature responsiveness to acute mental stress.
What is the current status of trial NCT07138443?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2025-08. Estimated completion is 2026-08.
What conditions does trial NCT07138443 study?
This clinical trial studies the following conditions: Stress, Mental Stress.
What interventions are being tested in trial NCT07138443?
The interventions under investigation include: Melatonin 3 MG Oral Tablet (DIETARY_SUPPLEMENT), Placebo Oral Tablet (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT07138443?
This trial is sponsored by Baylor University, which has 33 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07138443 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stress
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07138443's enrollment target sits among peer trials
20 142nd of 152 higher than 8 of 152 other Stress trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stress trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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