Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01673087 · ClinicalTrials.gov registry record · Phase 1
Stress Biomarkers:Attaching Biological Meaning to Field Friendly Salivary Measures
A Phase 1 study of Stress, sponsored by University of Michigan.
- Completed
- Registry status
- Phase 1
- Development phase
- 256
- Enrollment target
- 1
- Study location
NCT01673087: Completed Phase 1 study of Stress, sponsored by University of Michigan.
NCT01673087 is a Phase 1 study of Stress that has completed, run by University of Michigan. The registered enrollment target is 256 participants, below the 784-participant average among 152 other Stress trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01673087, a Phase 1 study of Stress, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 256 participants
- Enrollment target
- 1
- Study location
Study Summary
Cortisol is a stress hormone that can be measured in saliva. This has provided a convenient way to evaluate the biological impact of day-to-day stressors that people encounter as they go about their lives, since saliva is so easy to collect. However, the biological meaning of saliva cortisol measures has never been carefully examined. The goal of this study is to collect saliva from a large group of people as they go about their every-day lives, to measure their cortisol levels, and then study them in the laboratory where Investigators can learn more about how their stress response system (which produces cortisol) is really functioning. Investigators can then determine much more precisely what saliva cortisol levels really mean in terms of stress system biology. This will allow investigators to obtain much more useful information from the next decade of research on naturalistic stress and its biological impact using saliva cortisol measures, helping investigators to understand how stress undermines health and how to combat this effect.
Primary Outcome
cortisol measured in saliva and in blood.
Conditions Studied
Interventions
- DRUG Dexamethasone
- DRUG Metyrapone
- DRUG Cortrosyn
- DRUG Corticorelin ovine triflutate
Study Locations (1)
Michigan
- University of Michigan Health System - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 256 participants |
| Start Date | 2012-10 |
| Est. Completion | 2017-08-15 |
| Phase | Phase 1 |
What the finished NCT01673087 record still lists
NCT01673087 is an interventional study that assigns participants to a tested intervention. The registered 256 participants enrollment target is mid-sized for trials with a published cap, below the 784-participant average among 152 other Stress trials with a reported enrollment target (67% lower).
The record links to 1 condition, with Stress appearing as the primary indexed condition, and to 4 interventions - of which Dexamethasone is the first listed.
NCT01673087 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT01673087 about?
NCT01673087 is a clinical study titled "Stress Biomarkers:Attaching Biological Meaning to Field Friendly Salivary Measures". Cortisol is a stress hormone that can be measured in saliva. This has provided a convenient way to evaluate the biological impact of day-to-day stressors that people encounter as they go about their lives, since saliva is so easy to collect. However, the biological meaning of saliva cortisol measure...
What is the current status of trial NCT01673087?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 256 participants. The study started on 2012-10. Estimated completion is 2017-08-15.
What conditions does trial NCT01673087 study?
This clinical trial studies the following conditions: Stress.
What interventions are being tested in trial NCT01673087?
The interventions under investigation include: Dexamethasone (DRUG), Metyrapone (DRUG), Cortrosyn (DRUG), Corticorelin ovine triflutate (DRUG).
Who is sponsoring clinical trial NCT01673087?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01673087 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stress
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01673087's enrollment target sits among peer trials
256 24th of 152 higher than 129 of 152 other Stress trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stress trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Effects of Cannabidiol on Stress and Nicotine Withdrawal
RECRUITING · Phase 1
-
Impact of OnabotulinumtoxinA (BOTOX®) on Stress
RECRUITING · Phase 1
-
Study of Cannabidiol and Neuroimaging on Stress
RECRUITING · Phase 1
-
The Effects of Smell on Mood and Physical Responses
COMPLETED · Phase 1
-
Decreasing Stress and Improving Self-control With "Stress in Control" (Sync) Training
COMPLETED · Phase 1
-
Surviving Daily Life
RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02464696 · 256 participants · NA
Non-invasive Ventilation in Reducing the Need for Intubation in Patients With Cancer and Respiratory Failure
- NCT03793062 · 256 participants
Genetic and Epigenetic Basis of Chronic Wounds
- NCT04322318 · 256 participants · Phase 2
A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT
- NCT04468360 · 256 participants · Phase 2
Facilitation of Extinction Retention and Reconsolidation Blockade in PTSD
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia