Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04997356 · ClinicalTrials.gov registry record · NA
Hostile Bias Modification Training (HBMT) Study
A NA study of Stress and Aggression, sponsored by Walter Reed Army Institute of Research (WRAIR).
- Completed
- Registry status
- NA
- Development phase
- 165
- Enrollment target
- 1
- Study location
NCT04997356: Completed NA study of Stress and Aggression, sponsored by Walter Reed Army Institute of Research (WRAIR).
NCT04997356 is a NA study of Stress and Aggression that has completed, run by Walter Reed Army Institute of Research (WRAIR). The registered enrollment target is 165 participants, below the 785-participant average among 152 other Stress trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04997356, a NA study of Stress and Aggression, has completed, sponsored by Walter Reed Army Institute of Research (WRAIR).
- COMPLETED
- Registry status
- NA
- Development phase
- 165 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary objective of the present protocol is to evaluate the effectiveness of real HBMT versus placebo on reducing HAB and aggression. The secondary objectives of the present protocol are: 1. Investigate the role of individual difference variables on HAB, interpersonal aggression, and effects of HBMT. 2. Collect vocal recording data to inform the development of algorithms to predict emotional stress from changes in speech.
Primary Outcome
8-item self-reported hostile attribution bias to ambiguously hostile or unambiguously hostile feedback (0-4). Higher scores indicate more bias.
Conditions Studied
Interventions
- BEHAVIORAL Hostile Bias Modification Training
- BEHAVIORAL Other training
Study Locations (1)
Maryland
- Walter Reed Army Institute of Research - Silver Spring
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 165 participants |
| Start Date | 2021-08-12 |
| Est. Completion | 2023-05-15 |
| Phase | NA |
What the finished NCT04997356 record still lists
NCT04997356 is an interventional study that assigns participants to a tested intervention. The registered 165 participants enrollment target is mid-sized for trials with a published cap, below the 785-participant average among 152 other Stress trials with a reported enrollment target (79% lower).
The record links to 3 conditions, with Stress appearing as the primary indexed condition, and to 2 interventions - of which Hostile Bias Modification Training is the first listed.
NCT04997356 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04997356 about?
NCT04997356 is a clinical study titled "Hostile Bias Modification Training (HBMT) Study". The primary objective of the present protocol is to evaluate the effectiveness of real HBMT versus placebo on reducing HAB and aggression. The secondary objectives of the present protocol are: 1. Investigate the role of individual difference variables on HAB, interpersonal aggression, and effects ...
What is the current status of trial NCT04997356?
This trial is currently completed. It is a NA study. The enrollment target is 165 participants. The study started on 2021-08-12. Estimated completion is 2023-05-15.
What conditions does trial NCT04997356 study?
This clinical trial studies the following conditions: Stress, Aggression, Anger.
What interventions are being tested in trial NCT04997356?
The interventions under investigation include: Hostile Bias Modification Training (BEHAVIORAL), Other training (BEHAVIORAL).
Who is sponsoring clinical trial NCT04997356?
This trial is sponsored by Walter Reed Army Institute of Research (WRAIR), which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04997356 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stress
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04997356's enrollment target sits among peer trials
165 39th of 152 higher than 114 of 152 other Stress trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stress trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Mindfulness-Based Intervention With a Supplement for Stress-Related Problems in College Students Across Multiple Sites (4SITE)
RECRUITING · NA
-
Digital Intervention for Physical Activity
RECRUITING · NA
-
Cocooned Moms Study
RECRUITING · NA
-
Student Exercise and Sleep Timing Study - Part 2
RECRUITING · NA
-
Smartphone-based Cognitive Emotion Regulation Training for Unpaid Primary Caregivers of Persons With Alzheimer's Disease
RECRUITING · NA
-
ACT for HIV-Positive Men
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02387255 · 165 participants
Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms
- NCT03351348 · 165 participants · Phase 3
Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control
- NCT03830320 · 165 participants · Phase 1
Positron Emission Tomography (PET) Imaging of Thrombosis
- NCT04289571 · 165 participants · Phase 1
Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI