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NCT05142267 · ClinicalTrials.gov registry record · NA

Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms

A NA study of Opioid Use Disorder and Stress, sponsored by Vanderbilt University Medical Center.

Recruiting
Registry status
NA
Development phase
120
Enrollment target
1
Study location

NCT05142267 is a NA study of Opioid Use Disorder and Stress that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 120 participants, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05142267, a NA study of Opioid Use Disorder and Stress, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.

RECRUITING
Registry status
NA
Development phase
120 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to see how stress influences the effects of opioid pain medications often used to help relieve back pain. The study will help to learn more about how high stress levels could increase risk for pain medication misuse.

Interventions

  • DRUG Placebo
  • DRUG Oxycodone
  • DRUG Naloxone

Study Locations (1)

Tennessee

  • Vanderbilt University Medical Center - Nashville

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2022-03-02
Est. Completion 2026-07-31
Phase NA

What the Registry Record Tells You About NCT05142267

The ClinicalTrials.gov registry entry for NCT05142267 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (97% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Opioid Use Disorder appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT05142267 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT05142267 about?

NCT05142267 is a clinical study titled "Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms". The purpose of this study is to see how stress influences the effects of opioid pain medications often used to help relieve back pain. The study will help to learn more about how high stress levels could increase risk for pain medication misuse.

What is the current status of trial NCT05142267?

This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2022-03-02. Estimated completion is 2026-07-31.

What conditions does trial NCT05142267 study?

This clinical trial studies the following conditions: Opioid Use Disorder, Stress, Back Pain.

What interventions are being tested in trial NCT05142267?

The interventions under investigation include: Placebo (DRUG), Oxycodone (DRUG), Naloxone (DRUG).

Who is sponsoring clinical trial NCT05142267?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05142267 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.