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NCT06557707 · ClinicalTrials.gov registry record
Cardiovascular Health & Early Stress
A clinical trial of Stress, sponsored by Virginia Commonwealth University.
- Recruiting
- Registry status
- 120
- Enrollment target
- 1
- Study location
NCT06557707: Recruiting study of Stress, sponsored by Virginia Commonwealth University.
NCT06557707 is a study of Stress that is actively recruiting participants, run by Virginia Commonwealth University. The registered enrollment target is 120 participants, below the 785-participant average among 152 other Stress trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06557707, a study of Stress, is actively recruiting participants, sponsored by Virginia Commonwealth University.
- RECRUITING
- Registry status
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
Childhood adversity is highly prevalent, with 59% of the U.S. population reporting at least one adverse childhood experience (ACE). Substantial evidence links childhood adversity to cardiometabolic disease later in the life course, including heart disease, diabetes, and stroke, which are 3 of the top 10 causes of mortality in the United States. ACEs encompass many possible traumatic and distressing experiences, including abuse, neglect, or severe household dysfunctions. It is not surprising that the experience of those extreme events during the first decade of life has tremendous implications for the individual's psychological and physical health.
Primary Outcome
This test examines how the blood vessels respond to different challenges and expand. It is used to characterize the cardiovascular health of the subject's blood vessels. Different events and substances will be used (under an IND) to test how the blood vessels react. The test is completed using Laser Doppler Speckle Contrast. We will measure how much the blood vessels dilate. Greater dilation, better vascular function.
Conditions Studied
Interventions
- OTHER Childhood stress
Study Locations (1)
Virginia
- Virginia Commonwealth University - Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2022-01-20 |
| Est. Completion | 2028-12 |
What NCT06557707 shows while recruiting
NCT06557707 is an observational study that tracks outcomes without assigning an intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 785-participant average among 152 other Stress trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Stress appearing as the primary indexed condition, and to 1 intervention - of which Childhood stress is the first listed.
NCT06557707 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT06557707 about?
NCT06557707 is a clinical study titled "Cardiovascular Health & Early Stress". Childhood adversity is highly prevalent, with 59% of the U.S. population reporting at least one adverse childhood experience (ACE). Substantial evidence links childhood adversity to cardiometabolic disease later in the life course, including heart disease, diabetes, and stroke, which are 3 of the to...
What is the current status of trial NCT06557707?
This trial is currently recruiting. The enrollment target is 120 participants. The study started on 2022-01-20. Estimated completion is 2028-12.
What conditions does trial NCT06557707 study?
This clinical trial studies the following conditions: Stress.
What interventions are being tested in trial NCT06557707?
The interventions under investigation include: Childhood stress (OTHER).
Who is sponsoring clinical trial NCT06557707?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06557707 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stress
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06557707's enrollment target sits among peer trials
120 52nd of 152 higher than 94 of 152 other Stress trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stress trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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