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NCT07001930 · ClinicalTrials.gov registry record · Phase 1

Effects of Cannabidiol on Stress and Nicotine Withdrawal

A Phase 1 study of Stress and Nicotine Dependence, sponsored by Johns Hopkins University.

Recruiting
Registry status
Phase 1
Development phase
90
Enrollment target
1
Study location

NCT07001930 is a Phase 1 study of Stress and Nicotine Dependence that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 90 participants, below the 786-participant average among 152 other Stress trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07001930, a Phase 1 study of Stress and Nicotine Dependence, is actively recruiting participants, sponsored by Johns Hopkins University.

RECRUITING
Registry status
Phase 1
Development phase
90 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to examine the effect of doses of cannabidiol (CBD) during exposure to stress and nicotine withdrawal in nicotine users. The main objectives of the study include examining the effect CBD has on stress, tobacco dependence, tobacco withdrawal, and sex differences between these types of stress. Participants will be administered CBD and exposed to stress. Biological and subjective measures will be collected. Participants may be asked to stop use for 24 hours. Researchers will also investigate withdrawal effects between participants who have not smoked nicotine in 24 hours and those who have continued to smoke before each session.

Interventions

  • DRUG Epidiolex

Study Locations (1)

Maryland

  • Behavioral Pharmacology Research Unit - Baltimore

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2025-08-25
Est. Completion 2029-09-01
Phase Phase 1

Sponsor

Johns Hopkins University

1,448 total trials

What the Registry Record Tells You About NCT07001930

The ClinicalTrials.gov registry entry for NCT07001930 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 152 other Stress trials with a reported enrollment target (89% lower). The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Stress appearing as the primary indexed condition, and to 1 intervention - of which Epidiolex is the first listed.

NCT07001930 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT07001930 about?

NCT07001930 is a clinical study titled "Effects of Cannabidiol on Stress and Nicotine Withdrawal". The purpose of this study is to examine the effect of doses of cannabidiol (CBD) during exposure to stress and nicotine withdrawal in nicotine users. The main objectives of the study include examining the effect CBD has on stress, tobacco dependence, tobacco withdrawal, and sex differences between t...

What is the current status of trial NCT07001930?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 90 participants. The study started on 2025-08-25. Estimated completion is 2029-09-01.

What conditions does trial NCT07001930 study?

This clinical trial studies the following conditions: Stress, Nicotine Dependence, Tobacco Smoking, CBD.

What interventions are being tested in trial NCT07001930?

The interventions under investigation include: Epidiolex (DRUG).

Who is sponsoring clinical trial NCT07001930?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07001930 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.