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Seizures clinical trials
Every US clinical trial registered for Seizures — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
40 US clinical trials · 19 currently recruiting
The research picture
Seizures has 40 registered US clinical trials, 19 of them open to new participants right now — about 48% of the total.
- 19
- recruiting participants now
- 48%
- of trials open to enrollment
- 6
- in Phase 3–4 (later-stage)
- 4
- top sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
De-identified UNMH EEG Corpus Database Creation With Fully De-identified Clinical Information
University of New Mexi
NCT05140265
Pediatric Dose Optimization for Seizures in Emergency Medical Services
Stanford University
NCT05121324
Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children
Children's Hospital of Philadelphia
NCT03419260
Longitudinal Study of Neurogenetic Disorders
Columbia University
NCT03492060
Investigating Epilepsy: Screening and Evaluation
National Institute of Neurological Disorders and Stroke (NINDS)
NCT03478852
Genetic Markers of Cardiovascular Disease in Epilepsy
Mayo Clinic
NCT02824822
Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy
University of Florida
NCT02216500
Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
SK Life Science
NCT05219617
Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy
Neuroelectrics Corporation
NCT04770337
Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases
Ayal A. Aizer, MD
NCT07130786
Impact of Capturing Ictal Events With Ultra-long-term Ambulatory EEG Monitoring With Remote EEG Monitoring System.
Epitel
NCT06027749
Oxygen Toxicity: Mechanisms in Humans
Duke University
NCT05761756
Pharmacological Modulation of Brain Oscillations in Memory Processing
University of Texas Southwestern Medical Center
NCT05594017
PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrest
University of California, San Francis
NCT06401707
Ear-Seizure Detection (EarSD) Study
Felicia Chu
NCT06598189
Modulating Movement Intention Via Cortical Stimulation
NYU Langone Health
NCT03233399
buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest
University of California, San Francis
NCT05851391
Glioblastoma Remote Monitoring and Care - Research Protocol
Case Comprehensive Cancer Center
NCT06129760
Acute Effects of Focused Ultrasound Modulation on EEG Behavior in Status Epilepticus Patients
Yale University
NCT05784805
Neural Circulatory Control and SUDEP Risk.
Mayo Clinic
NCT02813980
RNS System LGS Feasibility Study
NeuroPace
NCT05339126
BHV-7000 Responsive Neurostimulation System (RNS) Study
Yale University
NCT07125261
Does Gabapentin and Lamotriginel Have Significantly Fewer Side-effects While Providing Equal or Better Seizure Control Than the Current Drug Choice, Carbamazepine, for the Treatment of Seizures in the Elderly.
US Department of Veterans Affairs
NCT00007670
Childhood Absence Epilepsy Rx PK-PD-Pharmacogenetics Study
Children's Hospital Medical Center, Cincinnati
NCT00088452
Intranasal Midazolam Versus Rectal Diazepam for Treatment of Seizures
University of Utah
NCT00326612
Retigabine (Adjunctive Therapy) Efficacy and Safety Study for Partial Onset Refractory Seizures in Epilepsy
GlaxoSmithKline
NCT00232596
Revisiting Survey Investigating Why Patients Are Not Receiving Home Anti-convulsant Medication Prior to Surgery/or Procedure Involving General Anesthesia
Vidya Raman
NCT01897974
Hypovitaminosis D in Neurocritical Patients
University of Utah
NCT02881957
Clobazam in Patients With Lennox-Gastaut Syndrome
Lundbeck
NCT00518713
Search for Genes Influencing Childhood Absence Epilepsy (CAE) Study
Icahn School of Medicine at Mount Sinai
NCT00041951
Metabolic Abnormalities in Children With Epilepsy
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00001325
Cannabidiol Oral Solution in Pediatric Participants With Treatment-resistant Seizure Disorders
INSYS Therapeutics
NCT02324673
Crossover Bioequivalence Study of Oxcarbazepine 600 mg Suspension Under Fed Conditions
Roxane Laboratories
NCT01703468
Evaluation of StatNet Device for Electroencephalogram (EEG) Recordings
Beth Israel Deaconess Medical Center
NCT03103425
Phase I Trail for Intramuscular Administration of Midazolam Using An Autoinjector
U.S. Army Office of the Surgeon General
NCT00534378
Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene
Children's Hospital Medical Center, Cincinnati
NCT03892798
Transcranial Magnetic Stimulation for the Treatment of Poorly Controlled Partial Epilepsy
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00001666
Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase Deficiency
National Institute of Neurological Disorders and Stroke (NINDS)
NCT02019667
Effect of Perampanel on Peritumoral Hyperexcitability in HGG
Dana-Farber Cancer Institute
NCT04497142
Brain Tissue Swelling and Seizure Activity in Inactive Cysticercosis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00001912
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 7 |
| Phase 3 | 6 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Seizures Trial Landscape
ClinicalTrials.gov lists 40 US studies indexed under Seizures, and 19 of those are currently open to recruitment — roughly 48% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Seizures shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Seizures is led by National Institute of Neurological Disorders and Stroke (NINDS) with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 40 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Seizures?
PlainTrial tracks 40 US clinical trials for Seizures, of which 19 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Seizures?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.