Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Human Immunodeficiency Virus

Open-data reference.

40 US clinical trials · 12 currently recruiting

Active & Recent Trials

RECRUITING 768 participants

Harm Reduction in HIV Primary Care for PLWH Who Use Drugs

University of Pittsburgh

NCT05404750

RECRUITING Phase 3 400 participants

V+PSF-M for Tobacco Cessation in HIV Care in India

University of Colorado, Denver

NCT05786547

RECRUITING Phase 3 400 participants

Cefixime Clinical Trial

University of Southern California

NCT04958122

RECRUITING 280 participants

Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease

National Cancer Institute (NCI)

NCT03300830

RECRUITING NA 260 participants

Text Education About Cardiovascular Health and HIV (TEACH-HIV)

University of California, San Francis

NCT05642858

RECRUITING Phase 4 250 participants

Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV

Louisiana State University Health Sciences Center in New Orleans

NCT05266898

RECRUITING Phase 2 100 participants

Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus

M.D. Anderson Cancer Center

NCT02479698

RECRUITING Phase 2 95 participants

Baricitinib for Reduction of HIV - CNS

William Tyor

NCT05452564

RECRUITING Phase 4 60 participants

Low Dose Naltrexone for Pain in Patients With HIV

Emory University

NCT05537935

RECRUITING Phase 1 50 participants

Lenacapavir Intensification to Disrupt HIV Reservoirs in Virologically Suppressed People With HIV Receiving Antiretroviral Therapy

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06819176

RECRUITING 30 participants

Tulane Abdominal Transplant Institute (TATI) of Solid Organ Transplantation of HIV-Positive Recipients From HIV-Positive Donors

Tulane University

NCT05159466

RECRUITING NA 20 participants

Gut Microbiota-Mediated Inflammatory Interactions Between AUD and HIV Infection

Rush University Medical Center

NCT06139224

ACTIVE NOT RECRUITING NA 850 participants

Cross-disciplinary HIV Integrated Mental Health Support Intervention

Emory University

NCT04833829

ACTIVE NOT RECRUITING NA 830 participants

Integration of Hypertension Management Into HIV Care in Nigeria

NYU Langone Health

NCT04704336

ACTIVE NOT RECRUITING NA 500 participants

Increasing PrEP Use in High-Risk Social Networks of African-American MSM in Underserved Low-Risk Cities

Medical College of Wisconsin

NCT03823209

ACTIVE NOT RECRUITING 123 participants

Health Information for Infected Veterans

VA Office of Research and Development

NCT03190317

ACTIVE NOT RECRUITING Early Phase 1 100 participants

Impact of HIV-1 and Aging on Mucosal Vaccine Responses

VA Eastern Colorado Health Care System

NCT03729778

ACTIVE NOT RECRUITING Phase 1 28 participants

3BNC117-LS and 10-1074-LS Plus N-803 (bNAb+N-803)

Rockefeller University

NCT05245292

COMPLETED NA 706 participants

Smoking Cessation for HIV/AIDS Patients

M.D. Anderson Cancer Center

NCT00502827

COMPLETED NA 330 participants

Improving Drug Adherence Among Adolescents in Uganda Using SMS Reminders

RAND

NCT02128087

COMPLETED 159 participants

HIV, Buprenorphine, and the Criminal Justice System (STRIDE2)

Yale University

NCT03583138

COMPLETED 146 participants

Body Image in Youth With HIV

St. Jude Children's Research Hospital

NCT01673750

COMPLETED NA 141 participants

The OPENS Trial: Offering Women PrEP (Aim 2)

University of California, San Francis

NCT05619497

COMPLETED Phase 4 100 participants

HIV Non-Occupational Post-Exposure Prophylaxis

Kenneth H. Mayer, MD

NCT01855867

COMPLETED Phase 1 77 participants

First-in-human Study of 10-1074-LS Alone and in Combination With 3BNC117-LS

Rockefeller University

NCT03554408

COMPLETED Phase 2 53 participants

Elite Controller and ART-treated HIV+ Statin Versus ASA Treatment Intervention Study

National Institute of Allergy and Infectious Diseases (NIAID)

NCT02081638

COMPLETED Phase 4 52 participants

Buprenorphine and Integrated HIV Care

Yale University

NCT00317460

COMPLETED Phase 4 43 participants

Biomarkers for Event-driven PrEP Adherence

Emory University

NCT04298697

COMPLETED Phase 4 31 participants

Switching Undetectables to Selzentry

St. Hope Foundation

NCT01866267

COMPLETED NA 30 participants

CBSM Intervention Via mHealth to Ameliorate HIV-related Fatigue

Medical University of South Carolina

NCT03149094

COMPLETED 21 participants

Problems With Immune Recovery in the Gut Tissue

University of Minnesota

NCT01460433

COMPLETED Phase 4 21 participants

Treatment of Acute Hepatitis C Virus in HIV Co-Infection

University of California, San Francis

NCT00845676

COMPLETED Phase 1 18 participants

Pharmacokinetic Interactions Between an Herbal Medicine (African Potato) and Antiretroviral Agents (Lopinavir/Ritonavir)

University of California, San Francis

NCT01227590

COMPLETED Phase 1 18 participants

Evaluation of the Safety of a Polyvalent Virus in Healthy Adults

St. Jude Children's Research Hospital

NCT00187044

COMPLETED NA 18 participants

The Happy Older Latinos Are Active (HOLA) Health Promotion Study in HIV-Infected Latino Men

University of Miami

NCT03839212

COMPLETED Phase 4 16 participants

Post-Exposure Prophylaxis in Health Care Workers

Henry Ford Health System

NCT01234116

COMPLETED NA 16 participants

Trauma Intervention for Affect Regulation, AIDS, and Substances

University of Miami

NCT02923141

COMPLETED 13 participants

Relationship of Tenofovir With HIV-1 Suppression in ex Vivo Tissue in Adolescents

University of California, Los Angeles

NCT02134431

COMPLETED Phase 1 12 participants

First in Human Study of TLC-ART 101 (ACTU 2001)

University of Washington

NCT05850728

COMPLETED Phase 1 8 participants

Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women

Thomas Jefferson University

NCT04283656

Phase Distribution

PhaseTrial count
Early Phase 1 8
Phase 2 3
Phase 3 2
Phase 4 8

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Human Immunodeficiency Virus Trial Landscape

ClinicalTrials.gov lists 40 US studies indexed under Human Immunodeficiency Virus, and 12 of those are currently open to recruitment — roughly 30% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Human Immunodeficiency Virus shows 10 late-stage studies (Phase 3 and Phase 4 combined) alongside 11 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Human Immunodeficiency Virus is led by University of California, San Francis with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 40 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Human Immunodeficiency Virus?

PlainTrial tracks 40 US clinical trials for Human Immunodeficiency Virus, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Human Immunodeficiency Virus?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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