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ClinicalTrials.gov 12 recruiting now full pipeline

Human Immunodeficiency Virus: full-pipeline trial registry

12 of 40 indexed Human Immunodeficiency Virus trials are currently recruiting.

Corpus placement: #368 of 28,707 conditions by registered trial count.

40 US clinical trials · 12 currently recruiting · #368 of 28,707 conditions by registered trial count

Human Immunodeficiency Virus: 40 US clinical trials tracked, 12 recruiting.

Human Immunodeficiency Virus is the subject of 40 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, San Francisco, running 4 of these trials.

Enrollment posture brief

Registry condition human-immunodeficiency-virus

OPEN 12 | RECR 30% | LATE 10 | EARLY 11 | RANK #368 | SPON 4

Nearest open-share peer: Adrenocortical Carcinoma (30% recruiting · 10 trials)

Anatomic Stage IIIA Breast C35%Human Papilloma Virus35%Human Immunodeficiency V (th…30%Heart Failure, Congestive12.5%Cocaine Dependence7.5%
Open-enrollment share among volume-matched conditions near Human Immunodeficiency Virus

Human Immunodeficiency Virus lists 12 open slots (30% of 40 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Human Immunodeficiency Virus on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Human Immunodeficiency Virus is recruiting below its size-band peers.

    12 of 40 indexed trials (30%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Human Immunodeficiency Virus trials is spread across many organizations.

    University of California, San Francisco accounts for 4 of 40 trials (10%). 29 distinct sponsors appear on at least one study for this condition label.

  3. Typical Human Immunodeficiency Virus enrolment sits around 77 participants.

    Median target enrolment is 77 among the 40 trials that report a genuine target (sentinel values excluded). 22 of those (55%) plan for fewer than 100 participants.

  4. Human Immunodeficiency Virus research is mostly interventional.

    32 interventional and 8 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 18Phase 23Phase 32Phase 48

Open and recent trials

40 total, page 1 of 1

RECRUITING 768 participants

Harm Reduction in HIV Primary Care for PLWH Who Use Drugs

University of Pittsburgh

NCT05404750

RECRUITING Phase 3 400 participants

V+PSF-M for Tobacco Cessation in HIV Care in India

University of Colorado, Denver

NCT05786547

RECRUITING Phase 3 400 participants

Cefixime Clinical Trial

University of Southern California

NCT04958122

RECRUITING 280 participants

Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease

National Cancer Institute (NCI)

NCT03300830

RECRUITING NA 260 participants

Text Education About Cardiovascular Health and HIV (TEACH-HIV)

University of California, San Francisco

NCT05642858

RECRUITING Phase 4 250 participants

Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV

Louisiana State University Health Sciences Center in New Orleans

NCT05266898

RECRUITING Phase 2 100 participants

Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus

M.D. Anderson Cancer Center

NCT02479698

RECRUITING Phase 2 95 participants

Baricitinib for Reduction of HIV - CNS

William Tyor

NCT05452564

RECRUITING Phase 4 60 participants

Low Dose Naltrexone for Pain in Patients With HIV

Emory University

NCT05537935

RECRUITING Phase 1 50 participants

Lenacapavir Intensification to Disrupt HIV Reservoirs in Virologically Suppressed People With HIV Receiving Antiretroviral Therapy

National Institute of Allergy and Infectious Diseases (NIAID)

NCT06819176

RECRUITING 30 participants

Tulane Abdominal Transplant Institute (TATI) of Solid Organ Transplantation of HIV-Positive Recipients From HIV-Positive Donors

Tulane University

NCT05159466

RECRUITING NA 20 participants

Gut Microbiota-Mediated Inflammatory Interactions Between AUD and HIV Infection

Rush University Medical Center

NCT06139224

ACTIVE NOT RECRUITING NA 850 participants

Cross-disciplinary HIV Integrated Mental Health Support Intervention

Emory University

NCT04833829

ACTIVE NOT RECRUITING NA 830 participants

Integration of Hypertension Management Into HIV Care in Nigeria

NYU Langone Health

NCT04704336

ACTIVE NOT RECRUITING NA 500 participants

Increasing PrEP Use in High-Risk Social Networks of African-American MSM in Underserved Low-Risk Cities

Medical College of Wisconsin

NCT03823209

ACTIVE NOT RECRUITING 123 participants

Health Information for Infected Veterans

VA Office of Research and Development

NCT03190317

ACTIVE NOT RECRUITING Early Phase 1 100 participants

Impact of HIV-1 and Aging on Mucosal Vaccine Responses

VA Eastern Colorado Health Care System

NCT03729778

ACTIVE NOT RECRUITING Phase 1 28 participants

3BNC117-LS and 10-1074-LS Plus N-803 (bNAb+N-803)

Rockefeller University

NCT05245292

COMPLETED NA 706 participants

Smoking Cessation for HIV/AIDS Patients

M.D. Anderson Cancer Center

NCT00502827

COMPLETED NA 330 participants

Improving Drug Adherence Among Adolescents in Uganda Using SMS Reminders

RAND

NCT02128087

COMPLETED 159 participants

HIV, Buprenorphine, and the Criminal Justice System (STRIDE2)

Yale University

NCT03583138

COMPLETED 146 participants

Body Image in Youth With HIV

St. Jude Children's Research Hospital

NCT01673750

COMPLETED NA 141 participants

The OPENS Trial: Offering Women PrEP (Aim 2)

University of California, San Francisco

NCT05619497

COMPLETED Phase 4 100 participants

HIV Non-Occupational Post-Exposure Prophylaxis

Kenneth H. Mayer, MD

NCT01855867

COMPLETED Phase 1 77 participants

First-in-human Study of 10-1074-LS Alone and in Combination With 3BNC117-LS

Rockefeller University

NCT03554408

COMPLETED Phase 2 53 participants

Elite Controller and ART-treated HIV+ Statin Versus ASA Treatment Intervention Study

National Institute of Allergy and Infectious Diseases (NIAID)

NCT02081638

COMPLETED Phase 4 52 participants

Buprenorphine and Integrated HIV Care

Yale University

NCT00317460

COMPLETED Phase 4 43 participants

Biomarkers for Event-driven PrEP Adherence

Emory University

NCT04298697

COMPLETED Phase 4 31 participants

Switching Undetectables to Selzentry

St. Hope Foundation

NCT01866267

COMPLETED NA 30 participants

CBSM Intervention Via mHealth to Ameliorate HIV-related Fatigue

Medical University of South Carolina

NCT03149094

COMPLETED 21 participants

Problems With Immune Recovery in the Gut Tissue

University of Minnesota

NCT01460433

COMPLETED Phase 4 21 participants

Treatment of Acute Hepatitis C Virus in HIV Co-Infection

University of California, San Francisco

NCT00845676

COMPLETED Phase 1 18 participants

Pharmacokinetic Interactions Between an Herbal Medicine (African Potato) and Antiretroviral Agents (Lopinavir/Ritonavir)

University of California, San Francisco

NCT01227590

COMPLETED Phase 1 18 participants

Evaluation of the Safety of a Polyvalent Virus in Healthy Adults

St. Jude Children's Research Hospital

NCT00187044

COMPLETED NA 18 participants

The Happy Older Latinos Are Active (HOLA) Health Promotion Study in HIV-Infected Latino Men

University of Miami

NCT03839212

COMPLETED Phase 4 16 participants

Post-Exposure Prophylaxis in Health Care Workers

Henry Ford Health System

NCT01234116

COMPLETED NA 16 participants

Trauma Intervention for Affect Regulation, AIDS, and Substances

University of Miami

NCT02923141

COMPLETED 13 participants

Relationship of Tenofovir With HIV-1 Suppression in ex Vivo Tissue in Adolescents

University of California, Los Angeles

NCT02134431

COMPLETED Phase 1 12 participants

First in Human Study of TLC-ART 101 (ACTU 2001)

University of Washington

NCT05850728

COMPLETED Phase 1 8 participants

Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women

Thomas Jefferson University

NCT04283656

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 3
Phase 3 2
Phase 4 8

Named interventions

Most-linked intervention names on Human Immunodeficiency Virus records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

10-1074-LS Drug
2 trials
3BNC117-LS Drug
2 trials
flexible sigmoidoscopy or colonoscopy with biopsies Device
1 trials
Pegylated interferon alfa-2a + Ribavirin Drug
1 trials
Single Dose Elivitegravir (150mg), Combicistat (150mg), Emtricitabine (200mg), Tenofovir DF (300mg) Drug
1 trials
TLC-ART Drug
1 trials
buprenorphine Drug
1 trials
Estradiol 2mg Drug
1 trials

US sites by state

Facility locations filed on Human Immunodeficiency Virus trials. A trial with sites in several states counts in each.

California 7 trials
Maryland 4 trials
Georgia 4 trials
Florida 4 trials
Texas 3 trials
Pennsylvania 3 trials
New York 3 trials
Tennessee 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Human Immunodeficiency Virus page

40 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Human Immunodeficiency Virus condition card totals 40 registered trials; most-linked intervention 10-1074-LS; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.