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Heart Failure, Congestive
Open-data reference.
34 US clinical trials · 4 currently recruiting
Active & Recent Trials
Prospective Observational Study of the ICD in Sudden Cardiac Death Prevention
Johns Hopkins University
NCT00733590
Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism
Johns Hopkins University
NCT00181259
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Procyrion
NCT05677100
Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts
Heart Center Research
NCT06218199
Cardiovascular Health Study (CHS)
National Heart, Lung, and Blood Institute (NHLBI)
NCT00005133
Comparison of Noninvasive vs. Invasive Hemodynamic Measurements
Nihon Kohden
NCT06689215
My Recordable On-Demand Audio Discharge Instructions
The Cleveland Clinic
NCT02901314
Occluded Artery Trial (OAT)
NYU Langone Health
NCT00004562
Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease
Duke University
NCT00023595
Efficacy and Safety of Relaxin for the Treatment of Acute Heart Failure
Corthera, Inc.(formerly BAS Medical, Inc.), a member of the Novartis group of companies
NCT00520806
IMMEDIATE Trial - Out of Hospital Administration of Glucose, Insulin and Potassium.
Tufts Medical Center
NCT00091507
Help Veterans Experience Less Pain Study (HELP-Vets)
US Department of Veterans Affairs
NCT00230932
Multidisciplinary Inpatient Palliative Care Intervention
Kaiser Permanente
NCT00325611
Telephone Intervention in Heart Failure Patients
US Department of Veterans Affairs
NCT00057057
Enhancing Caregiver Support for Heart Failure Patients: the CarePartner Study
US Department of Veterans Affairs
NCT00555360
Reversal of Ventricular Remodeling With Toprol-XL
AstraZeneca
NCT00038077
The Purpose of This Study is to Determine if Eplerenone is Effective in Treatment of Mild to Moderate Heart Failure
Pfizer's Upjohn has merged with Mylan to form Viatris
NCT00082589
Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Destination Therapy
Abbott Medical Devices
NCT00121485
Insomnia Self-Management in Heart Failure
Yale University
NCT02660385
Exercise After an ICD
University of Washington
NCT00522340
Heart Pressure Assessment Study With Tolvaptan to Treat Congestive Heart Failure
Otsuka Pharmaceutical Development & Commercialization
NCT00132886
Collaborative Care for Heart Failure Patients With the Metabolic Syndrome
Baylor College of Medicine
NCT00293852
Effects of Carvedilol on Health Outcomes in Heart Failure
Denver Health and Hospital Authority
NCT00381030
Exercise Effect on Aerobic Capacity and QOL in Heart Failure
US Department of Veterans Affairs
NCT00013221
A Multi-center, Placebo-controlled Study to Evaluate the Safety of GSK716155 and Its Effects on Myocardial Metabolism, Myocardial Function, and Exercise Capacity in Patients With NYHA Class II/III Congestive Heart Failure
GlaxoSmithKline
NCT01357850
PIE II: Pharmacological Intervention in the Elderly II
Wake Forest University
NCT00123955
Dose Escalation Study of KW-3902 on Diuresis in Subjects With Congestive Heart Failure (CHF).
NovaCardia, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT00159627
A Family Intervention for Improving Self-Care of Patients With Heart Failure
US Department of Veterans Affairs
NCT00645489
Biventricular Pacing In Patients With Left Ventricular Dysfunction After Cardiovascular Surgery
Corewell Health East
NCT00321295
Registry of Patients With CardioMEMS
University of Pennsylvania
NCT02729922
Statin Therapy in Heart Failure: Potential Mechanisms of Benefit
University of California, Los Angeles
NCT00233480
Hemodynamic Response to Exercise in HFpEF Patients After Upregulation of SERCA2a
Benjamin Levine
NCT02772068
Transforming Psychotherapy for Chronically Ill Patients
US Department of Veterans Affairs
NCT00520429
Effect of Chronic Changes in Heart Rate on Congestive Heart Failure
University of Maryland, Baltimore
NCT00389649
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 3 |
| Phase 2 | 5 |
| Phase 3 | 6 |
| Phase 4 | 5 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Heart Failure, Congestive Trial Landscape
ClinicalTrials.gov lists 34 US studies indexed under Heart Failure, Congestive, and 4 of those are currently open to recruitment — roughly 12% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Heart Failure, Congestive shows 11 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Heart Failure, Congestive is led by US Department of Veterans Affairs with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 34 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Heart Failure, Congestive?
PlainTrial tracks 34 US clinical trials for Heart Failure, Congestive, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Heart Failure, Congestive?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.