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NCT00001325 · ClinicalTrials.gov registry record
Metabolic Abnormalities in Children With Epilepsy
A clinical trial of Seizures and Metabolic Disease, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 80
- Enrollment target
- 1
- Study location
NCT00001325 is a study of Seizures and Metabolic Disease that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 80 participants, below the 933-participant average among 39 other Seizures trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00001325, a study of Seizures and Metabolic Disease, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is designed to use positron emission tomography to measure brain energy use. Positron Emission Tomography (PET) is a technique used to investigate the functional activity of the brain. The PET technique allows doctors to study the normal processes of the brain (central nervous system) of normal individuals and patients with neurologic illnesses without physical / structural damage to the brain. When a region of the brain is active, it uses more fuel in the form of oxygen and sugar (glucose). As the brain uses more fuel it produces more waste products, carbon dioxide and water. Blood carries fuel to the brain and waste products away from the brain. As brain activity increases blood flow to and from the area of activity increases also. Researchers can label a sugar with a small radioactive molecule called FDG (fluorodeoxyglucose). As areas of the brain use more sugar the PET scan will detect the FDG and show the areas of the brain that are active. By using this technique researchers hope to answer the following questions; 4\. Are changes in brain energy use (metabolism) present early in the course of epilepsy 5\. Do changes in brain metabolism match the severity of patient's seizures 6\. Do changes in metabolism occur over time or in response to drug therapy
Conditions Studied
Interventions
- DRUG 18 FDG
Study Locations (1)
Maryland
- National Institute of Neurological Disorders and Stroke (NINDS) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 1992-04 |
| Est. Completion | 2004-06 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00001325
The ClinicalTrials.gov registry entry for NCT00001325 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 933-participant average among 39 other Seizures trials with a reported enrollment target (91% lower). The listed sponsor is National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Seizures appearing as the primary indexed condition, and to 1 intervention - of which 18 FDG is the first listed.
NCT00001325 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT00001325 about?
NCT00001325 is a clinical study titled "Metabolic Abnormalities in Children With Epilepsy". This study is designed to use positron emission tomography to measure brain energy use. Positron Emission Tomography (PET) is a technique used to investigate the functional activity of the brain. The PET technique allows doctors to study the normal processes of the brain (central nervous system) of ...
What is the current status of trial NCT00001325?
This trial is currently completed. The enrollment target is 80 participants. The study started on 1992-04. Estimated completion is 2004-06.
What conditions does trial NCT00001325 study?
This clinical trial studies the following conditions: Seizures, Metabolic Disease, Partial Epilepsy, Infantile Spasms, Generalized Epilepsy.
What interventions are being tested in trial NCT00001325?
The interventions under investigation include: 18 FDG (DRUG).
Who is sponsoring clinical trial NCT00001325?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001325 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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