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NCT05761756 · ClinicalTrials.gov registry record · NA
Oxygen Toxicity: Mechanisms in Humans
A NA study of Seizures and Hypercapnia, sponsored by Duke University.
- Recruiting
- Registry status
- NA
- Development phase
- 62
- Enrollment target
- 1
- Study location
NCT05761756 is a NA study of Seizures and Hypercapnia that is actively recruiting participants, run by Duke University. The registered enrollment target is 62 participants, below the 933-participant average among 39 other Seizures trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05761756, a NA study of Seizures and Hypercapnia, is actively recruiting participants, sponsored by Duke University.
- RECRUITING
- Registry status
- NA
- Development phase
- 62 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn about the mechanisms of oxygen toxicity in scuba divers. The main questions it aims to answer are: * How does the training of respiratory muscles affect oxygen toxicity? * How do environmental factors, such as sleep deprivation, the ingestion of commonly utilized medications, and chronic exposure to carbon dioxide, impact the risk of oxygen toxicity? * How does immersion in water affect the development of oxygen toxicity? Participants will be asked to do the following: * Undergo a basic screening exam composed of health history, vital signs, and some respiratory function tests * Train their respiratory muscles at regular intervals * Exercise on a cycle ergometer both in dry conditions and underwater/under pressure in the context of medication, sleep deprivation, or carbon dioxide exposure Researchers will compare the performance of each subject before and after the possible interventions described above to see if there are changes in exercise performance, respiratory function, cerebral blood flow, and levels of gene expression.
Conditions Studied
Interventions
- DRUG Methylphenidate
- BEHAVIORAL Sleep Deprivation
- DRUG Caffeine
- DRUG Carbon Dioxide
Study Locations (1)
North Carolina
- Duke University Health Sustem - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 62 participants |
| Start Date | 2023-11-28 |
| Est. Completion | 2026-08-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05761756
The ClinicalTrials.gov registry entry for NCT05761756 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 62 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 933-participant average among 39 other Seizures trials with a reported enrollment target (93% lower). The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Seizures appearing as the primary indexed condition, and to 4 interventions - of which Methylphenidate is the first listed.
NCT05761756 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.
Frequently Asked Questions
What is clinical trial NCT05761756 about?
NCT05761756 is a clinical study titled "Oxygen Toxicity: Mechanisms in Humans". The goal of this clinical trial is to learn about the mechanisms of oxygen toxicity in scuba divers. The main questions it aims to answer are: * How does the training of respiratory muscles affect oxygen toxicity? * How do environmental factors, such as sleep deprivation, the ingestion of commonly ...
What is the current status of trial NCT05761756?
This trial is currently recruiting. It is a NA study. The enrollment target is 62 participants. The study started on 2023-11-28. Estimated completion is 2026-08-31.
What conditions does trial NCT05761756 study?
This clinical trial studies the following conditions: Seizures, Hypercapnia, Oxygen Toxicity.
What interventions are being tested in trial NCT05761756?
The interventions under investigation include: Methylphenidate (DRUG), Sleep Deprivation (BEHAVIORAL), Caffeine (DRUG), Carbon Dioxide (DRUG).
Who is sponsoring clinical trial NCT05761756?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05761756 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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