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NCT00001666 · ClinicalTrials.gov registry record

Transcranial Magnetic Stimulation for the Treatment of Poorly Controlled Partial Epilepsy

A clinical trial of Seizures and Partial Epilepsy, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

Completed
Registry status
32
Enrollment target
1
Study location

NCT00001666: Completed study of Seizures and Partial Epilepsy, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

NCT00001666 is a study of Seizures and Partial Epilepsy that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 32 participants, below the 934-participant average among 39 other Seizures trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00001666, a study of Seizures and Partial Epilepsy, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

COMPLETED
Registry status
32 participants
Enrollment target
1
Study location

Study Summary

Transcranial Magnetic Stimulation (TMS) is a non-invasive technique that can be used to stimulate brain activity and gather information about brain function. It is very useful when studying the areas of the brain related to motor activity (motor cortex, corticospinal tract, and corpus callosum). Epilepsy is a condition associated with seizures as a result of an over excitable cerebral cortex. Despite the introduction of several new antiepileptic medications, less than half of the patients diagnosed with partial epilepsy are well controlled. However, studies have shown that non-invasive stimulation of the brain can decrease the excitability of the cerebral cortex. Researchers are interested in the potential therapeutic effects of TMS on patients with epilepsy that have responded poorly to standard medication. This study will use TMS to decrease the excitability of the areas of the brain responsible for seizures.

Conditions Studied

Seizures Partial Epilepsy

Interventions

  • DEVICE Cadwell High-Speed Magnetoelectric Stimulator
  • DEVICE Magpro High-Speed Magnetoelectric Stimulator

Study Locations (1)

Maryland

  • National Institute of Neurological Disorders and Stroke (NINDS) - Bethesda

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 1997-03
Est. Completion 2002-06
National Institute of Neurological Disorders and Stroke (NINDS)

567 total trials

What the finished NCT00001666 record still lists

NCT00001666 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 934-participant average among 39 other Seizures trials with a reported enrollment target (97% lower).

The record links to 2 conditions, with Seizures appearing as the primary indexed condition, and to 2 interventions - of which Cadwell High-Speed Magnetoelectric Stimulator is the first listed.

NCT00001666 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT00001666 about?

NCT00001666 is a clinical study titled "Transcranial Magnetic Stimulation for the Treatment of Poorly Controlled Partial Epilepsy". Transcranial Magnetic Stimulation (TMS) is a non-invasive technique that can be used to stimulate brain activity and gather information about brain function. It is very useful when studying the areas of the brain related to motor activity (motor cortex, corticospinal tract, and corpus callosum). Ep...

What is the current status of trial NCT00001666?

This trial is currently completed. The enrollment target is 32 participants. The study started on 1997-03. Estimated completion is 2002-06.

What conditions does trial NCT00001666 study?

This clinical trial studies the following conditions: Seizures, Partial Epilepsy.

What interventions are being tested in trial NCT00001666?

The interventions under investigation include: Cadwell High-Speed Magnetoelectric Stimulator (DEVICE), Magpro High-Speed Magnetoelectric Stimulator (DEVICE).

Who is sponsoring clinical trial NCT00001666?

This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00001666 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Seizures

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00001666's enrollment target sits among peer trials

32 31st of 39 higher than 9 of 39 other Seizures trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Seizures trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT00001666, the US trial registry maintained by the National Library of Medicine. NCT00001666 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.