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NCT00001912 · ClinicalTrials.gov registry record

Brain Tissue Swelling and Seizure Activity in Inactive Cysticercosis

A clinical trial of Seizures and Cysticercosis, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
6
Enrollment target
2
Study locations

NCT00001912: Completed study of Seizures and Cysticercosis, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00001912 is a study of Seizures and Cysticercosis that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 6 participants, below the 934-participant average among 39 other Seizures trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00001912, a study of Seizures and Cysticercosis, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
6 participants
Enrollment target
2
Study locations

Study Summary

This study will examine what causes seizures in patients with cysticercosis (pork tapeworm infection). A better understanding of this could lead to improved methods of controlling or preventing seizures. In humans, the pork tapeworm (Taenia solium) lives in the small intestine. The parasite's microscopic eggs travel around the body-including to the brain-where they develop into cysts. Usually, the cysts don't cause symptoms until they die. Then, they provoke an inflammatory reaction that irritates the brain, causing seizures and other symptoms. The inflammation eventually goes away, but the dead cysts remain. Calcium deposits often form where the cysts are. Some of the calcified cysts develop swelling around them that seem to be associated with the development of seizures. This study will explore how and why these dead, calcified cysts continue to cause seizures. In so doing, it will try to determine: 1) the best diagnostic imaging method for detecting swelling around the cysts; 2) how often swelling occurs; and 3) what makes some cysts prone to swelling and related seizure activity, while others are not. Patients with cysticercosis who have had seizures or who have known or possible swelling around calcified cysts will be studied with various tests, including magnetic resonance imaging (MRI), computed tomography (CT) scans, electroencephalography (EEG), blood tests, and possibly lumbar puncture. Patients will be studied for two cycles of seizures (during active and quiet periods) or a maximum 4 years.

Conditions Studied

Seizures Cysticercosis Cysts

Study Locations (2)

Maryland

  • National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda

Other

  • Universidad Peruana Cayetano Heredia - Lima

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 1999-08-10
Est. Completion 2012-04-04
National Institute of Allergy and Infectious Diseases (NIAID)

2,006 total trials

What the finished NCT00001912 record still lists

NCT00001912 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 934-participant average among 39 other Seizures trials with a reported enrollment target (99% lower).

The record links to 3 conditions, with Seizures appearing as the primary indexed condition, and to 0 interventions.

NCT00001912 reports a single indexed study location in Maryland, Other.

Frequently Asked Questions

What is clinical trial NCT00001912 about?

NCT00001912 is a clinical study titled "Brain Tissue Swelling and Seizure Activity in Inactive Cysticercosis". This study will examine what causes seizures in patients with cysticercosis (pork tapeworm infection). A better understanding of this could lead to improved methods of controlling or preventing seizures. In humans, the pork tapeworm (Taenia solium) lives in the small intestine. The parasite's micro...

What is the current status of trial NCT00001912?

This trial is currently completed. The enrollment target is 6 participants. The study started on 1999-08-10. Estimated completion is 2012-04-04.

What conditions does trial NCT00001912 study?

This clinical trial studies the following conditions: Seizures, Cysticercosis, Cysts.

Who is sponsoring clinical trial NCT00001912?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00001912 being conducted?

This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Seizures

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00001912's enrollment target sits among peer trials

6 39th of 39 higher than 1 of 39 other Seizures trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Seizures trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT00001912, the US trial registry maintained by the National Library of Medicine. NCT00001912 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.