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NCT07130786 · ClinicalTrials.gov registry record · Phase 2

Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

A Phase 2 study of Seizures and Brain Metastases, Adult, sponsored by Ayal A. Aizer, MD.

Recruiting
Registry status
Phase 2
Development phase
150
Enrollment target
1
Study location

NCT07130786 is a Phase 2 study of Seizures and Brain Metastases, Adult that is actively recruiting participants, run by Ayal A. Aizer, MD. The registered enrollment target is 150 participants, below the 931-participant average among 39 other Seizures trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07130786, a Phase 2 study of Seizures and Brain Metastases, Adult, is actively recruiting participants, sponsored by Ayal A. Aizer, MD.

RECRUITING
Registry status
Phase 2
Development phase
150 participants
Enrollment target
1
Study location

Study Summary

This is a randomized trial for patients with brain metastases in the primary motor cortex who have not had seizures to receive either the prophylactic anti-seizure medication levetiracetam (also known by its trade name Keppra) or proceed with standard of care management, which does not currently include prophylactic levetiracetam. Patients who enroll to this trial will be randomized to receive prophylactic levetiracetam or not receive prophylactic levetiracetam.

Interventions

  • DRUG Levetiracetam (Keppra)

Study Locations (1)

Massachusetts

  • Brigham and Women's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2025-12-23
Est. Completion 2030-02
Phase Phase 2

Sponsor

Ayal A. Aizer, MD

2 total trials

What the Registry Record Tells You About NCT07130786

The ClinicalTrials.gov registry entry for NCT07130786 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 931-participant average among 39 other Seizures trials with a reported enrollment target (84% lower). The listed sponsor is Ayal A. Aizer, MD, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Seizures appearing as the primary indexed condition, and to 1 intervention - of which Levetiracetam (Keppra) is the first listed.

NCT07130786 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT07130786 about?

NCT07130786 is a clinical study titled "Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases". This is a randomized trial for patients with brain metastases in the primary motor cortex who have not had seizures to receive either the prophylactic anti-seizure medication levetiracetam (also known by its trade name Keppra) or proceed with standard of care management, which does not currently inc...

What is the current status of trial NCT07130786?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 150 participants. The study started on 2025-12-23. Estimated completion is 2030-02.

What conditions does trial NCT07130786 study?

This clinical trial studies the following conditions: Seizures, Brain Metastases, Adult, Brain Metastases From Non-small Cell Lung Cancer (NSCLC), Brain Metastases From Extra-cranial Solid Tumors, Primary Motor Cortex.

What interventions are being tested in trial NCT07130786?

The interventions under investigation include: Levetiracetam (Keppra) (DRUG).

Who is sponsoring clinical trial NCT07130786?

This trial is sponsored by Ayal A. Aizer, MD, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07130786 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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