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Respiratory Failure: full-pipeline trial registry
13 of 41 indexed Respiratory Failure trials are currently recruiting.
Corpus placement: #357 of 28,707 conditions by registered trial count.
41 US clinical trials · 13 currently recruiting · #357 of 28,707 conditions by registered trial count
Respiratory Failure: 41 US clinical trials tracked, 13 recruiting.
Respiratory Failure is the subject of 41 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Beth Israel Deaconess Medical Center, running 3 of these trials.
Enrollment posture brief
Registry condition respiratory-failure
OPEN 13 | RECR 32% | LATE 5 | EARLY 5 | RANK #357 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Childhood Obesity (32% recruiting · 44 trials)
Respiratory Failure lists 13 open slots (32% of 41 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Respiratory Failure on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Respiratory Failure is recruiting below its size-band peers.
13 of 41 indexed trials (31.7%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Respiratory Failure trials is spread across many organizations.
Beth Israel Deaconess Medical Center accounts for 3 of 41 trials (7.3%). 34 distinct sponsors appear on at least one study for this condition label.
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Typical Respiratory Failure enrolment sits around 128 participants.
Median target enrolment is 128 among the 41 trials that report a genuine target (sentinel values excluded). 14 of those (34.1%) plan for fewer than 100 participants.
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Respiratory Failure research is mostly interventional.
35 interventional and 6 observational studies make up this index (85.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
41 total, page 1 of 1
Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients
University of Colorado, Denver
NCT06501118
End-Tidal Oxygen for Intubation in the Emergency Department
Sydney Local Health District
NCT06578468
Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome
Beth Israel Deaconess Medical Center
NCT06066502
Hospital Airway Resuscitation Trial
Montefiore Medical Center
NCT05520762
Respiratory Knowledge Portal Computer and Phone Application to Improve Quality of Mechanical Ventilation by Reducing the Number of Ventilator Associated Events, Injury Created by the Ventilator and Unsafe Setting of Alarms.
The University of Texas Medical Branch, Galveston
NCT06737432
Analgesia-First Sedation in Trauma Patients
MemorialCare Health System
NCT05751863
Transpulmonary Pressure Guided Mechanical Ventilation Weaning in Obesity
University of Mississippi Medical Center
NCT05530434
Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research
Baylor Research Institute
NCT04664192
The Family Perspectives Project Pilot Trial
Matthew Modes
NCT06039501
Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention
Johns Hopkins University
NCT06341972
A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure
Yale University
NCT06671015
Low and High Flow Suctioning in Intubated Infants
Columbia University
NCT06443970
Supraglottic Airway for Resuscitation in Preemies
University of Pennsylvania
NCT07419438
A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning
AgileMD
NCT05893420
Long Term Outcomes of Patients With COVID-19
University of Chicago
NCT04360538
CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients
McMaster University
NCT03471247
Feasibility of the Comfort Measures Only Time Out (CMOT)
Beth Israel Deaconess Medical Center
NCT05861323
Veno-venous Extracorporeal Membrane Oxygenation (VV-ECMO) Heparin Study
Baylor Research Institute
NCT04496362
The Effects of Vertical Position on Gas Exchange in Patients With Respiratory Failure
University of Chicago
NCT01705119
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
Massachusetts General Hospital
NCT02105298
Prevention of Severe Acute Respiratory Failure in Patients With PROOFCheck
Albert Einstein College of Medicine
NCT02488174
Heart And Lung Failure - Pediatric INsulin Titration Trial
Boston Children's Hospital
NCT01565941
Oral Suction Intervention to Reduce Aspiration and Ventilator Events: NO-ASPIRATE
University of Central Florida
NCT02284178
Preventing Hypoxemia With Manual Ventilation During Endotracheal Intubation (PreVent) Trial
Vanderbilt University Medical Center
NCT03026322
Proning Early in Awake COVID-19 Hypoxic Respiratory Failure (PREACHR) Study
New York Hospital Queens
NCT05130541
FiO2 Closed Loop Control Ventilation
Zoll Medical Corporation
NCT02810080
Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure
Fred Hutchinson Cancer Center
NCT01335932
Inspiratory Muscle Training in Ventilator Dependent Patients
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00419458
Pragmatic Investigation of Volume Targeted Ventilation-1
Wake Forest University Health Sciences
NCT03909854
Prognostic Value of Point of Care Cardiac and Lung Ultrasound in COVID-19
University of Pennsylvania
NCT04379544
Safety and Efficacy of Endotracheal Intubation Using Glidescope Video-Laryngoscope
Beth Israel Medical Center
NCT01683526
CYCLE Pilot Randomized Trial
McMaster University
NCT02377830
Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients
St. Joseph's Healthcare Hamilton
NCT05456542
Use of Lung Ultrasound to Diagnose the Etiology of Respiratory Failure in a PICU.
University of Wisconsin, Madison
NCT03744169
Vitamin D in Ventilated ICU Patients
Emory University
NCT01372995
The Use of the GlideScope Ranger in Pediatric Critical Care Transport
Akron Children's Hospital
NCT01054183
CTSI-iPad for Vented Patient Communication
Medical College of Wisconsin
NCT03163823
Nebulized Hypertonic Saline for Mechanically Ventilated Children
University Hospitals Cleveland Medical Center
NCT01945944
Assessment of Breathing Using an Under-bed Weighing Scale
Beth Israel Deaconess Medical Center
NCT04736212
Inhaled Nitric Oxide by Oxygen Hood in Neonates
University of Alabama at Birmingham
NCT00732537
A Randomized, Controlled Trial of Inspiratory Muscle Training (IMT)in the ICU and CCU
Wake Forest University Health Sciences
NCT02003053
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 3 |
| Phase 3 | 3 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Respiratory Failure records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Respiratory Failure trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Respiratory Failure page
41 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 13 Respiratory Failure trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Beth Israel Deaconess Medical Center sponsors the most Respiratory Failure trials on record, review their full trial history before evaluating a specific study. See Beth Israel Deaconess Medical Center's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Respiratory Failure condition card totals 41 registered trials; most-linked intervention Direct Laryngoscopy; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.