Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03026322 · ClinicalTrials.gov registry record · NA
Preventing Hypoxemia With Manual Ventilation During Endotracheal Intubation (PreVent) Trial
A NA study of Respiratory Failure and Endotracheal Intubation, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 401
- Enrollment target
- 5
- Study locations
NCT03026322 is a NA study of Respiratory Failure and Endotracheal Intubation that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 401 participants, below the 4,514-participant average among 40 other Respiratory Failure trials with a reported enrollment target (91% lower). The trial reports 5 study locations across 4 states.
The verdict
NCT03026322, a NA study of Respiratory Failure and Endotracheal Intubation, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 401 participants
- Enrollment target
- 5
- Study locations
Study Summary
Complications are common during endotracheal intubation of critically ill adults. Manual ventilation between induction and intubation ("bag-valve-mask" ventilation) has been proposed as a means of preventing hypoxemia, the most common complication of intubation outside the operating room. Safety and efficacy data, however, are lacking. PreVent is a randomized trial comparing manual ventilation between induction and laryngoscopy to no manual ventilation between induction an laryngoscopy during endotracheal intubation of critically ill adults. The primary efficacy endpoint will be the lowest arterial oxygen saturation. The primary safety endpoints will be the lowest oxygen saturation, highest fraction of inspired oxygen, and highest positive end-expiratory pressure in the 24 hours after the procedure.
Conditions Studied
Interventions
- OTHER Manual Ventilation
- OTHER No Manual Ventilation
Study Locations (5)
Louisiana
- Louisiana State University School of Medicine - New Orleans
- Ochsner Health System - New Orleans
Alabama
- The University of Alabama at Birmingham - Birmingham
Tennessee
- Vanderbilt University Medical Center - Nashville
Washington
- Harborview Medical Center, University of Washington - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 401 participants |
| Start Date | 2017-03-15 |
| Est. Completion | 2018-07-06 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03026322
The ClinicalTrials.gov registry entry for NCT03026322 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 401 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,514-participant average among 40 other Respiratory Failure trials with a reported enrollment target (91% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Respiratory Failure appearing as the primary indexed condition, and to 2 interventions - of which Manual Ventilation is the first listed.
NCT03026322 reports 5 study locations spanning 4 distinct geographic areas - top geographies include Louisiana, Alabama, Tennessee.
Frequently Asked Questions
What is clinical trial NCT03026322 about?
NCT03026322 is a clinical study titled "Preventing Hypoxemia With Manual Ventilation During Endotracheal Intubation (PreVent) Trial". Complications are common during endotracheal intubation of critically ill adults. Manual ventilation between induction and intubation ("bag-valve-mask" ventilation) has been proposed as a means of preventing hypoxemia, the most common complication of intubation outside the operating room. Safety and...
What is the current status of trial NCT03026322?
This trial is currently completed. It is a NA study. The enrollment target is 401 participants. The study started on 2017-03-15. Estimated completion is 2018-07-06.
What conditions does trial NCT03026322 study?
This clinical trial studies the following conditions: Respiratory Failure, Endotracheal Intubation, Respiratory Failure With Hypoxia.
What interventions are being tested in trial NCT03026322?
The interventions under investigation include: Manual Ventilation (OTHER), No Manual Ventilation (OTHER).
Who is sponsoring clinical trial NCT03026322?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03026322 being conducted?
This trial has 5 study locations across Alabama, Louisiana, Tennessee, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Respiratory Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Analgesia-First Sedation in Trauma Patients
RECRUITING · NA
-
Hospital Airway Resuscitation Trial
RECRUITING · NA
-
Supraglottic Airway for Resuscitation in Preemies
RECRUITING · NA
-
The Family Perspectives Project Pilot Trial
RECRUITING · NA
-
End-Tidal Oxygen for Intubation in the Emergency Department
RECRUITING · NA
-
A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure
RECRUITING · NA
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.