Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03909854 · ClinicalTrials.gov registry record · NA
Pragmatic Investigation of Volume Targeted Ventilation-1
A NA study of Respiratory Failure and Acute Respiratory Distress Syndrome (ARDS), sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- NA
- Development phase
- 139
- Enrollment target
- 1
- Study location
NCT03909854: Completed NA study of Respiratory Failure and Acute Respiratory Distress Syndrome (ARDS), sponsored by Wake Forest University Health Sciences.
NCT03909854 is a NA study of Respiratory Failure and Acute Respiratory Distress Syndrome (ARDS) that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 139 participants, below the 4,521-participant average among 40 other Respiratory Failure trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03909854, a NA study of Respiratory Failure and Acute Respiratory Distress Syndrome (ARDS), has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- NA
- Development phase
- 139 participants
- Enrollment target
- 1
- Study location
Study Summary
This proposal will test the feasibility of implementing an assist volume control ventilation protocol in patients receiving mechanical ventilation in the medical intensive care unit. The trial will consist of a before-and-after trial design of block assignment to either adaptive pressure control (baseline) or assist volume control . This is a feasibility study looking at the management of patients in the ventilator.
Primary Outcome
The primary outcome for the PIVOT-1 pilot is feasibility of Assist Volume Control implementation. We define feasibility in this study as 80% of patients receiving Assist Volume Control within 1 hour of initiation of intensive care unit mechanical ventilation
Conditions Studied
Interventions
- PROCEDURE mode of mechanical ventilation
Study Locations (1)
North Carolina
- Wake Forest Baptist Medical Center - Winston-Salem
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 139 participants |
| Start Date | 2019-09-09 |
| Est. Completion | 2020-02-20 |
| Phase | NA |
What the finished NCT03909854 record still lists
NCT03909854 is an interventional study that assigns participants to a tested intervention. The registered 139 participants enrollment target is mid-sized for trials with a published cap, below the 4,521-participant average among 40 other Respiratory Failure trials with a reported enrollment target (97% lower).
The record links to 3 conditions, with Respiratory Failure appearing as the primary indexed condition, and to 1 intervention - of which mode of mechanical ventilation is the first listed.
NCT03909854 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT03909854 about?
NCT03909854 is a clinical study titled "Pragmatic Investigation of Volume Targeted Ventilation-1". This proposal will test the feasibility of implementing an assist volume control ventilation protocol in patients receiving mechanical ventilation in the medical intensive care unit. The trial will consist of a before-and-after trial design of block assignment to either adaptive pressure control (ba...
What is the current status of trial NCT03909854?
This trial is currently completed. It is a NA study. The enrollment target is 139 participants. The study started on 2019-09-09. Estimated completion is 2020-02-20.
What conditions does trial NCT03909854 study?
This clinical trial studies the following conditions: Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS), Ventilator Lung.
What interventions are being tested in trial NCT03909854?
The interventions under investigation include: mode of mechanical ventilation (PROCEDURE).
Who is sponsoring clinical trial NCT03909854?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03909854 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Respiratory Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03909854's enrollment target sits among peer trials
139 20th of 40 higher than 21 of 40 other Respiratory Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Respiratory Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Analgesia-First Sedation in Trauma Patients
RECRUITING · NA
-
Hospital Airway Resuscitation Trial
RECRUITING · NA
-
Supraglottic Airway for Resuscitation in Preemies
RECRUITING · NA
-
The Family Perspectives Project Pilot Trial
RECRUITING · NA
-
End-Tidal Oxygen for Intubation in the Emergency Department
RECRUITING · NA
-
A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT05645380 · 139 participants · Phase 2
Neoadjuvant TIL- and Response-Adapted Chemoimmunotherapy for TNBC
- NCT06239272 · 139 participants · Phase 1
NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)
- NCT06252220 · 139 participants · Phase 1
First in Human Study in Subjects With Obesity, But Otherwise Healthy
- NCT06537128 · 139 participants · NA
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI