Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04379544 · ClinicalTrials.gov registry record
Prognostic Value of Point of Care Cardiac and Lung Ultrasound in COVID-19
A clinical trial of Respiratory Failure and Coronavirus, sponsored by University of Pennsylvania.
- Completed
- Registry status
- 125
- Enrollment target
- 1
- Study location
NCT04379544: Completed study of Respiratory Failure and Coronavirus, sponsored by University of Pennsylvania.
NCT04379544 is a study of Respiratory Failure and Coronavirus that has completed, run by University of Pennsylvania. The registered enrollment target is 125 participants, below the 4,521-participant average among 40 other Respiratory Failure trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04379544, a study of Respiratory Failure and Coronavirus, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- 125 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a protocol-driven observational study of lung ultrasound and focused echocardiography images obtained in the Emergency Department (ED) and Intensive Care Unit (ICU) settings as a part of existing standard of care. The objectives of this study are as follows: 1. To characterize various clinical and cardiopulmonary ultrasound findings and describe their relationship with the clinical course of patients with COVID-19 in the ED and ICU. 2. To describe, develop, and validate a prediction tool that can accurately predict the need for invasive mechanical ventilation (IMV) and acute respiratory failure in COVID-19 patients using clinical, laboratory, and ultrasound data.
Primary Outcome
Number of patients requiring invasive mechanical ventilation and suffers from acute respiratory failure.
Conditions Studied
Interventions
- OTHER Observation only
Study Locations (1)
Pennsylvania
- University of Pennsylvania Health System - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 125 participants |
| Start Date | 2020-04-23 |
| Est. Completion | 2021-12-01 |
What the finished NCT04379544 record still lists
NCT04379544 is an observational study that tracks outcomes without assigning an intervention. The registered 125 participants enrollment target is mid-sized for trials with a published cap, below the 4,521-participant average among 40 other Respiratory Failure trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Respiratory Failure appearing as the primary indexed condition, and to 1 intervention - of which Observation only is the first listed.
NCT04379544 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT04379544 about?
NCT04379544 is a clinical study titled "Prognostic Value of Point of Care Cardiac and Lung Ultrasound in COVID-19". This is a protocol-driven observational study of lung ultrasound and focused echocardiography images obtained in the Emergency Department (ED) and Intensive Care Unit (ICU) settings as a part of existing standard of care. The objectives of this study are as follows: 1. To characterize various clini...
What is the current status of trial NCT04379544?
This trial is currently completed. The enrollment target is 125 participants. The study started on 2020-04-23. Estimated completion is 2021-12-01.
What conditions does trial NCT04379544 study?
This clinical trial studies the following conditions: Respiratory Failure, Coronavirus.
What interventions are being tested in trial NCT04379544?
The interventions under investigation include: Observation only (OTHER).
Who is sponsoring clinical trial NCT04379544?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04379544 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Respiratory Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04379544's enrollment target sits among peer trials
125 22nd of 40 higher than 19 of 40 other Respiratory Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Respiratory Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Analgesia-First Sedation in Trauma Patients
RECRUITING · NA
-
Hospital Airway Resuscitation Trial
RECRUITING · NA
-
Supraglottic Airway for Resuscitation in Preemies
RECRUITING · NA
-
The Family Perspectives Project Pilot Trial
RECRUITING · NA
-
End-Tidal Oxygen for Intubation in the Emergency Department
RECRUITING · NA
-
A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02717039 · 125 participants
Pharmacogenomics of Heparin-Induced Thrombocytopenia
- NCT02763033 · 125 participants · Phase 2
Dietary Manipulation of the Microbiome-metabolomic Axis for Mitigating GVHD in Allo HCT Patients
- NCT02793999 · 125 participants
Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia
- NCT03003299 · 125 participants · NA
PARTNER 3 Trial - Aortic Valve-in-Valve
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI