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NCT01945944 · ClinicalTrials.gov registry record · Phase 1
Nebulized Hypertonic Saline for Mechanically Ventilated Children
A Phase 1 study of Respiratory Failure, sponsored by University Hospitals Cleveland Medical Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT01945944: Completed Phase 1 study of Respiratory Failure, sponsored by University Hospitals Cleveland Medical Center.
NCT01945944 is a Phase 1 study of Respiratory Failure that has completed, run by University Hospitals Cleveland Medical Center. The registered enrollment target is 18 participants, below the 4,524-participant average among 40 other Respiratory Failure trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01945944, a Phase 1 study of Respiratory Failure, has completed, sponsored by University Hospitals Cleveland Medical Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
Children who need to be on a ventilator often have thick secretions/mucus in their lungs. These secretions can obstruct the breathing tube and their windpipe, which can worsen lung function and prolong the need for the ventilator. Hypertonic saline is a medicine that is used to thin out secretions in patients with cystic fibrosis (and other conditions). We hypothesize that having children on a ventilator inhale this medication will shorten the amount of time that they need to be on the ventilator.
Conditions Studied
Interventions
- DRUG Placebo (0.9% saline)
- DRUG Hypertonic saline (3%)
Study Locations (1)
Ohio
- Rainbow Babies and Children's Hospital (of Univ. Hospitals Case Med. Center) - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2013-10 |
| Est. Completion | 2014-05 |
| Phase | Phase 1 |
What the finished NCT01945944 record still lists
NCT01945944 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 4,524-participant average among 40 other Respiratory Failure trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Respiratory Failure appearing as the primary indexed condition, and to 2 interventions - of which Placebo (0.9% saline) is the first listed.
NCT01945944 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT01945944 about?
NCT01945944 is a clinical study titled "Nebulized Hypertonic Saline for Mechanically Ventilated Children". Children who need to be on a ventilator often have thick secretions/mucus in their lungs. These secretions can obstruct the breathing tube and their windpipe, which can worsen lung function and prolong the need for the ventilator. Hypertonic saline is a medicine that is used to thin out secretions i...
What is the current status of trial NCT01945944?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2013-10. Estimated completion is 2014-05.
What conditions does trial NCT01945944 study?
This clinical trial studies the following conditions: Respiratory Failure.
What interventions are being tested in trial NCT01945944?
The interventions under investigation include: Placebo (0.9% saline) (DRUG), Hypertonic saline (3%) (DRUG).
Who is sponsoring clinical trial NCT01945944?
This trial is sponsored by University Hospitals Cleveland Medical Center, which has 230 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01945944 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Respiratory Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01945944's enrollment target sits among peer trials
18 37th of 40 higher than 4 of 40 other Respiratory Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Respiratory Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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