Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Depression, Anxiety: early-phase trial registry
21 of 41 indexed Depression, Anxiety trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #357 of 28,707 conditions by registered trial count.
41 US clinical trials · 21 currently recruiting · #357 of 28,707 conditions by registered trial count
Depression, Anxiety: 41 US clinical trials tracked, 21 recruiting.
Depression, Anxiety is the subject of 41 registered US clinical trials on ClinicalTrials.gov, 21 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Northwestern University, running 2 of these trials.
Enrollment posture brief
Registry condition depression-anxiety
OPEN 21 | RECR 51% | LATE 1 | EARLY 6 | RANK #357 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Chronic Pancreatitis (51% recruiting · 43 trials)
Depression, Anxiety lists 21 open slots (51% of 41 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Depression, Anxiety on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Depression, Anxiety is recruiting above its size-band peers.
21 of 41 indexed trials (51.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Depression, Anxiety trials is spread across many organizations.
Northwestern University accounts for 2 of 41 trials (4.9%). 37 distinct sponsors appear on at least one study for this condition label.
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Typical Depression, Anxiety enrolment sits around 140 participants.
Median target enrolment is 140 among the 41 trials that report a genuine target (sentinel values excluded). 15 of those (36.6%) plan for fewer than 100 participants.
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Depression, Anxiety research is mostly interventional.
38 interventional and 3 observational studies make up this index (92.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
41 total, page 1 of 1
Prevention of Psychological Health Problems Via Integrated Operational Support
New York University
NCT06981598
Building Connections
Massachusetts General Hospital
NCT07091032
Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain
Washington University School of Medicine
NCT06978166
Harlem Strong Mental Health Coalition
City University of New York, School of Public Health
NCT05833555
Youth Emotional and Behavioral Treatment Study
Florida State University
NCT07296939
Mental Health in Primary Care
University of Miami
NCT05426057
Examining the Efficacy of a Digital Therapeutic to Prevent Suicidal Behaviors
University of Memphis
NCT06318962
Modulating Exercise Dosage to Improve Concussion Recovery
University of Colorado, Denver
NCT05434130
SUpport From PEeRs to Expand Access Study - Community
University of California, Berkeley
NCT07186816
Creative Arts Program to Reduce Burnout in Healthcare Professionals
University of Colorado, Denver
NCT04276922
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Brigham and Women's Hospital
NCT06376734
Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression
Laureate Institute for Brain Research
NCT06004115
Test of Target Engagement of Ambiguity Aversion
Northwestern University
NCT06962527
Training in Evidence-based Treatments in Psycho-Oncology
Massachusetts General Hospital
NCT05674357
Pilot Effectiveness Trial of an ACT Self-help Workbook Tailored Specifically for Prisons
University of Wisconsin, Madison
NCT06162624
Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients
West Virginia School of Osteopathic Medicine
NCT06049420
Promoting Active Therapy: Path to Wellness
Kansas State University
NCT06858189
Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision Loss
The Chicago Lighthouse
NCT07073521
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
Mclean Hospital
NCT05837104
Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy
M.D. Anderson Cancer Center
NCT06200155
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
Trustees of Dartmouth College
NCT06920238
Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD)
University of Utah
NCT04845542
A Tailored and Digital Approach to Address Equity and Support Well-being for Healthcare Workers in the Era of COVID
University of Pennsylvania
NCT05931432
Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery
KK Women's and Children's Hospital
NCT03408717
Health Questionnaire Study
University of California, Irvine
NCT06956378
The BEAR Therapeutic Program for Women
Stanford University
NCT04418778
Voice Activated Personal Assistant for Depression Among Older Adults
Northwestern University
NCT06114485
PRISM for Depression and Anxiety in Young Adults With Cancer
Dana-Farber Cancer Institute
NCT06502483
Effects of a Black Rice Extract and Anthocyanidin Metabolites on the Synthesis and Release of BDNF in Healthy Subjects
University of California, Davis
NCT06594848
Healthy Minds Comparison Study
University of Wisconsin, Madison
NCT06282523
iWellness Study to Evaluate a Mental Health App for Students
Harvard University
NCT05234970
Randomized Clinical Trial of a Multi-Modal Palliative Care Intervention
University of Colorado, Boulder
NCT04773639
Strong People Strength Training Study
Cornell University
NCT04203563
Change in Social Media Use and Well-being Among College Students Receiving a One-week Exercise or Mindfulness Intervention
Johns Hopkins Bloomberg School of Public Health
NCT06143852
Kintsugi Voice Device Study
Kintsugi Mindful Wellness
NCT05554042
Brief App-based Mood Monitoring and Mindfulness Intervention for First-year College Students
Lawrence University
NCT06348277
A Trauma-Informed Approach for Positive Youth Development for Montana Students
Montana State University
NCT04664855
Effect of Whole Blueberry Powder Consumption on Depression in a Central Louisiana Population
Louisiana State University, Baton Rouge
NCT04398784
Digital Behavioral Interventions in Inflammatory Bowel Disease
Montefiore Medical Center
NCT04861597
TODAY! A Mobile App Study
Ann & Robert H Lurie Children's Hospital of Chicago
NCT03534167
Developing Mental Health Supports for Autistic Students
Rutgers, The State University of New Jersey
NCT04926090
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 5 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Depression, Anxiety records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Depression, Anxiety trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Depression, Anxiety page
41 registered trials, 21 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 21 Depression, Anxiety trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Northwestern University sponsors the most Depression, Anxiety trials on record, review their full trial history before evaluating a specific study. See Northwestern University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Depression, Anxiety condition card totals 41 registered trials; most-linked intervention Placebo; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.