Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Depression, Anxiety
Open-data reference.
39 US clinical trials · 20 currently recruiting
Active & Recent Trials
Prevention of Psychological Health Problems Via Integrated Operational Support
New York University
NCT06981598
Building Connections
Massachusetts General Hospital
NCT07091032
Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain
Washington University School of Medicine
NCT06978166
Harlem Strong Mental Health Coalition
City University of New York, School of Public Health
NCT05833555
Youth Emotional and Behavioral Treatment Study
Florida State University
NCT07296939
Mental Health in Primary Care
University of Miami
NCT05426057
Modulating Exercise Dosage to Improve Concussion Recovery
University of Colorado, Denver
NCT05434130
SUpport From PEeRs to Expand Access Study - Community
University of California, Berkeley
NCT07186816
Creative Arts Program to Reduce Burnout in Healthcare Professionals
University of Colorado, Denver
NCT04276922
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Brigham and Women's Hospital
NCT06376734
Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression
Laureate Institute for Brain Research
NCT06004115
Test of Target Engagement of Ambiguity Aversion
Northwestern University
NCT06962527
Training in Evidence-based Treatments in Psycho-Oncology
Massachusetts General Hospital
NCT05674357
Pilot Effectiveness Trial of an ACT Self-help Workbook Tailored Specifically for Prisons
University of Wisconsin, Madison
NCT06162624
Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients
West Virginia School of Osteopathic Medicine
NCT06049420
Promoting Active Therapy: Path to Wellness
Kansas State University
NCT06858189
Developing Evidence-Based Cognitive Approaches to Improve Adjustment to Vision Loss
The Chicago Lighthouse
NCT07073521
Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
Mclean Hospital
NCT05837104
Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy
M.D. Anderson Cancer Center
NCT06200155
Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use
Trustees of Dartmouth College
NCT06920238
Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD)
University of Utah
NCT04845542
A Tailored and Digital Approach to Address Equity and Support Well-being for Healthcare Workers in the Era of COVID
University of Pennsylvania
NCT05931432
Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery
KK Women's and Children's Hospital
NCT03408717
Health Questionnaire Study
University of California, Irvine
NCT06956378
The BEAR Therapeutic Program for Women
Stanford University
NCT04418778
Voice Activated Personal Assistant for Depression Among Older Adults
Northwestern University
NCT06114485
PRISM for Depression and Anxiety in Young Adults With Cancer
Dana-Farber Cancer Institute
NCT06502483
Effects of a Black Rice Extract and Anthocyanidin Metabolites on the Synthesis and Release of BDNF in Healthy Subjects
University of California, Davis
NCT06594848
iWellness Study to Evaluate a Mental Health App for Students
Harvard University
NCT05234970
Randomized Clinical Trial of a Multi-Modal Palliative Care Intervention
University of Colorado, Boulder
NCT04773639
Strong People Strength Training Study
Cornell University
NCT04203563
Change in Social Media Use and Well-being Among College Students Receiving a One-week Exercise or Mindfulness Intervention
Johns Hopkins Bloomberg School of Public Health
NCT06143852
Kintsugi Voice Device Study
Kintsugi Mindful Wellness
NCT05554042
Brief App-based Mood Monitoring and Mindfulness Intervention for First-year College Students
Lawrence University
NCT06348277
A Trauma-Informed Approach for Positive Youth Development for Montana Students
Montana State University
NCT04664855
Effect of Whole Blueberry Powder Consumption on Depression in a Central Louisiana Population
Louisiana State University, Baton Rouge
NCT04398784
Digital Behavioral Interventions in Inflammatory Bowel Disease
Montefiore Medical Center
NCT04861597
TODAY! A Mobile App Study
Ann & Robert H Lurie Children's Hospital of Chicago
NCT03534167
Developing Mental Health Supports for Autistic Students
Rutgers, The State University of New Jersey
NCT04926090
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 1 |
| Phase 2 | 5 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Depression, Anxiety Trial Landscape
ClinicalTrials.gov lists 39 US studies indexed under Depression, Anxiety, and 20 of those are currently open to recruitment — roughly 51% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Depression, Anxiety shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Depression, Anxiety is led by Northwestern University with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 39 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Depression, Anxiety?
PlainTrial tracks 39 US clinical trials for Depression, Anxiety, of which 20 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Depression, Anxiety?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.