Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06671015 · ClinicalTrials.gov registry record · NA
A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure
A NA study of Respiratory Failure and Systolic Heart Failure, sponsored by Yale University.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT06671015 is a NA study of Respiratory Failure and Systolic Heart Failure that is actively recruiting participants, run by Yale University. The registered enrollment target is 50 participants, below the 4,523-participant average among 40 other Respiratory Failure trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06671015, a NA study of Respiratory Failure and Systolic Heart Failure, is actively recruiting participants, sponsored by Yale University.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This prospective, open-label randomized controlled pilot trial will enroll participants at the Yale New Haven Hospital. Patients with systolic heart failure, defined as an ejection fraction ≤40%, who require invasive mechanical ventilation (IMV) and are admitted to either the cardiac intensive care unit (CICU) or medical ICU (MICU) will be included. Subjects meeting eligibility criteria will be randomized 1:1 to one of the two treatment groups: * Intervention: Extubation to high-flow nasal cannula (HFNC) * Control: Extubation to non-invasive ventilation (NIV)
Conditions Studied
Interventions
- DEVICE Airvo 3
Study Locations (1)
Connecticut
- Yale New Haven Hospital (CICU or MICU) - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2025-10-04 |
| Est. Completion | 2026-02 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06671015
The ClinicalTrials.gov registry entry for NCT06671015 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,523-participant average among 40 other Respiratory Failure trials with a reported enrollment target (99% lower). The listed sponsor is Yale University, which has 1,492 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Respiratory Failure appearing as the primary indexed condition, and to 1 intervention - of which Airvo 3 is the first listed.
NCT06671015 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.
Frequently Asked Questions
What is clinical trial NCT06671015 about?
NCT06671015 is a clinical study titled "A Trial Comparing High-Flow Nasal Cannula Versus Noninvasive Ventilation on Reintubation and Post-Extubation Respiratory Failure in High-Risk Patients With Systolic Heart Failure". This prospective, open-label randomized controlled pilot trial will enroll participants at the Yale New Haven Hospital. Patients with systolic heart failure, defined as an ejection fraction ≤40%, who require invasive mechanical ventilation (IMV) and are admitted to either the cardiac intensive care ...
What is the current status of trial NCT06671015?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2025-10-04. Estimated completion is 2026-02.
What conditions does trial NCT06671015 study?
This clinical trial studies the following conditions: Respiratory Failure, Systolic Heart Failure.
What interventions are being tested in trial NCT06671015?
The interventions under investigation include: Airvo 3 (DEVICE).
Who is sponsoring clinical trial NCT06671015?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06671015 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Respiratory Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Analgesia-First Sedation in Trauma Patients
RECRUITING · NA
-
Hospital Airway Resuscitation Trial
RECRUITING · NA
-
Supraglottic Airway for Resuscitation in Preemies
RECRUITING · NA
-
The Family Perspectives Project Pilot Trial
RECRUITING · NA
-
End-Tidal Oxygen for Intubation in the Emergency Department
RECRUITING · NA
-
Low and High Flow Suctioning in Intubated Infants
RECRUITING · NA
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.