Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Dyslipidemia

Open-data reference.

41 US clinical trials · 7 currently recruiting

Active & Recent Trials

RECRUITING 1,500 participants

Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic Conditions

National Heart, Lung, and Blood Institute (NHLBI)

NCT06676046

RECRUITING NA 200 participants

Prescription of Step Counts for Targeted Changes in Body Composition and Cardiometabolic Risk in Overweight/Obese Adults

Kennesaw State University

NCT07221279

RECRUITING Phase 1 136 participants

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia

AstraZeneca

NCT06980428

RECRUITING NA 90 participants

Cottonseed Oil Versus Matched PUFA Effects

University of Georgia

NCT06382298

RECRUITING NA 75 participants

Intermittent Cottonseed Oil Consumption

University of Georgia

NCT07246408

RECRUITING NA 72 participants

A Novel Digital Tool Physicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors

University of Connecticut

NCT07238556

RECRUITING NA 20 participants

Targeting Metabolic Syndrome From the Emergency Department Through Mixed-Methods: Pilot Trial

Indiana University

NCT07119658

COMPLETED Phase 3 5,035 participants

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk Open-label Extension

Amgen

NCT02867813

COMPLETED Phase 3 1,445 participants

Evaluate Safety and Efficacy of ABT-335 in Combination With Rosuvastatin Calcium in Subjects With Multiple Abnormal Lipid Levels in the Blood

Abbott

NCT00300482

COMPLETED 824 participants

Association of Genes to Resistance to Weight Loss in Obese Patients

Interleukin Genetics

NCT00858221

COMPLETED Phase 3 682 participants

Safety and Efficacy Study Using ABT-335 (Investigational Drug) in Combination With Atorvastatin, to Study the Effects on Thickening of the Blood Vessel Wall in Patients With Abnormal Lipid (Fat) Levels in the Blood

AbbVie (prior sponsor, Abbott)

NCT00616772

COMPLETED NA 647 participants

The CREATE Wellness Study

Kaiser Permanente

NCT02302612

COMPLETED 450 participants

A Study of Physical and Metabolic Abnormalities in HIV Infected and Uninfected Children and Youth

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00069004

COMPLETED Phase 4 413 participants

Efficacy and Safety of Alirocumab Versus Usual Care on Top of Maximally Tolerated Statin Therapy in Patients With Type 2 Diabetes and Mixed Dyslipidemia (ODYSSEY DM-Dyslipidemia)

Sanofi

NCT02642159

COMPLETED Phase 3 412 participants

Efficacy and Safety of Valsartan and the Combination of Valsartan and Simvastatin

Novartis

NCT00385931

COMPLETED Phase 2 270 participants

Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women

National Heart, Lung, and Blood Institute (NHLBI)

NCT00666172

COMPLETED Phase 4 252 participants

A 12-Week Study Comparing Pitavastatin 4 mg vs. Pravastatin 40 mg in HIV-Infected Subjects

Kowa Research Institute

NCT01301066

COMPLETED NA 247 participants

Improving Adherence to Prescribing Guidelines for Cholesterol Lowering in Hospitalized Diabetic Patients

Washington University School of Medicine

NCT01113099

COMPLETED Phase 2 220 participants

Study of Atorvastatin/Fenofibrate (LCP-AtorFen) Combination Therapy in Dyslipidemia

Veloxis Pharmaceuticals

NCT00504829

COMPLETED Phase 4 218 participants

Fluvastatin in Adults With Dislipidemia With History of Muscle Problems

Novartis

NCT00125125

COMPLETED Phase 1 183 participants

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects

AstraZeneca

NCT05384262

COMPLETED Phase 4 140 participants

Colesevelam Treatment for Impaired Fasting Glucose During Niacin Therapy

Radiant Research

NCT01239004

COMPLETED NA 118 participants

Combined Behavioral and Pharmacological Intervention for Cardiovascular Risk Reduction in Diabetic Patients

Providence VA Medical Center

NCT00357955

COMPLETED Phase 1 99 participants

A Single and Multiple Ascending Dose Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of CAT-2003

Catabasis Pharmaceuticals

NCT01725594

COMPLETED Phase 2 99 participants

Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia

Catabasis Pharmaceuticals

NCT01912560

COMPLETED Phase 3 98 participants

Effect of a Decision Aid About Statin Use in Patients With Type 2 Diabetes Mellitus

Mayo Clinic

NCT00217061

COMPLETED Phase 1 81 participants

A Study to Investigate the Pharmacokinetics, Safety, Tolerability, and Efficacy of AZD0780 With Ezetimibe Combinations in Healthy Adults With Elevated LDL-C.

AstraZeneca

NCT06742853

COMPLETED Phase 2 81 participants

Safety Study of BMS-770767 in Subjects With Hypercholesterolemia

Bristol-Myers Squibb

NCT01058083

COMPLETED Phase 1 68 participants

Safety And Tolerability Of Multiple Doses Of PF-04950615 (RN316) In Subjects With Hypercholesterolemia

Pfizer

NCT01243151

COMPLETED Phase 2 54 participants

Preliminary Study of Safety and Efficacy of Policosanol

Rush University Medical Center

NCT00312923

COMPLETED NA 53 participants

Effect of Saturated Fat on Large Low-density Lipoprotein (LDL) and High-density Lipoprotein (HDL)

UCSF Benioff Children's Hospital Oakland

NCT00895141

COMPLETED NA 39 participants

Change of Fructose to Fat in South Asians

The Rogosin Institute

NCT01562782

COMPLETED NA 32 participants

Effects of Consuming Sugar-Sweetened Beverages With Meals for 10 Weeks

University of California, Davis

NCT01165853

COMPLETED NA 29 participants

Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

National Heart, Lung, and Blood Institute (NHLBI)

NCT04271735

COMPLETED Phase 1 26 participants

Effects of Niacin On Fatty Acid Trapping

University of Pennsylvania

NCT01984073

COMPLETED Phase 1 25 participants

ABT-335 (Choline Fenofibrate) Reverse Cholesterol Transport (RCT) Study

Radiant Research

NCT00673881

COMPLETED NA 24 participants

The Effect of Meal Composition on Blood Lipids

Texas Christian University

NCT02529709

COMPLETED NA 24 participants

Effects of Almond Intake on Atherogenic Lipoprotein Particles

UCSF Benioff Children's Hospital Oakland

NCT01792648

COMPLETED Phase 2 23 participants

Fenofibrate Treatment in SCI

VA Office of Research and Development

NCT02455336

COMPLETED NA 10 participants

Dietary Carbohydrate Type and Cardiovascular Disease (CVD) Risk Indicators

Tufts University

NCT01610661

COMPLETED NA 6 participants

Development of a Novel Method to Study in Vivo Fatty Acid Metabolism Using Stable Isotope Labeled Fatty Acids in Humans

Tufts University

NCT02312492

Phase Distribution

PhaseTrial count
Early Phase 1 7
Phase 2 6
Phase 3 5
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Dyslipidemia Trial Landscape

ClinicalTrials.gov lists 41 US studies indexed under Dyslipidemia, and 7 of those are currently open to recruitment — roughly 17% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Dyslipidemia shows 9 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Dyslipidemia is led by National Heart, Lung, and Blood Institute (NHLBI) with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 41 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Dyslipidemia?

PlainTrial tracks 41 US clinical trials for Dyslipidemia, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Dyslipidemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →