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NCT05456542 · ClinicalTrials.gov registry record · Phase 3
Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients
A Phase 3 study of Respiratory Failure, sponsored by St. Joseph's Healthcare Hamilton.
- Completed
- Registry status
- Phase 3
- Development phase
- 100
- Enrollment target
- 5
- Study locations
NCT05456542 is a Phase 3 study of Respiratory Failure that has completed, run by St. Joseph's Healthcare Hamilton. The registered enrollment target is 100 participants, below the 4,521-participant average among 40 other Respiratory Failure trials with a reported enrollment target (98% lower). The trial reports 5 study locations across 3 states.
The verdict
NCT05456542, a Phase 3 study of Respiratory Failure, has completed, sponsored by St. Joseph's Healthcare Hamilton.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 100 participants
- Enrollment target
- 5
- Study locations
Study Summary
The COSMIC trial will be a multicentred, national, parallel-group, pragmatic vanguard pilot trial.
Conditions Studied
Interventions
- DRUG Dexamethasone 4mg
- DIAGNOSTIC_TEST Cuff Leak Test
Study Locations (5)
Ontario
- Brantford General Hospital - Brantford
- St. Joseph's Healthcare Hamilton - Hamilton
- Niagara Health System - Saint Catherines
Texas
- The University of Texas Health Science Center at Houston - Houston
Other
- Al-Amiri Hospital - Kuwait City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2023-04-05 |
| Est. Completion | 2025-01-06 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05456542
The ClinicalTrials.gov registry entry for NCT05456542 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,521-participant average among 40 other Respiratory Failure trials with a reported enrollment target (98% lower). The listed sponsor is St. Joseph's Healthcare Hamilton, which has 3 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Respiratory Failure appearing as the primary indexed condition, and to 2 interventions - of which Dexamethasone 4mg is the first listed.
NCT05456542 reports 5 study locations spanning 3 distinct geographic areas - top geographies include Ontario, Texas, Other.
Frequently Asked Questions
What is clinical trial NCT05456542 about?
NCT05456542 is a clinical study titled "Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients". The COSMIC trial will be a multicentred, national, parallel-group, pragmatic vanguard pilot trial.
What is the current status of trial NCT05456542?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 100 participants. The study started on 2023-04-05. Estimated completion is 2025-01-06.
What conditions does trial NCT05456542 study?
This clinical trial studies the following conditions: Respiratory Failure.
What interventions are being tested in trial NCT05456542?
The interventions under investigation include: Dexamethasone 4mg (DRUG), Cuff Leak Test (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT05456542?
This trial is sponsored by St. Joseph's Healthcare Hamilton, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05456542 being conducted?
This trial has 5 study locations across Texas, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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