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ClinicalTrials.gov 275 recruiting now early-phase tilt #4 of 28,963 conditions

Prostate Cancer: early-phase trial registry

275 of 749 indexed Prostate Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #4 of 28,963 conditions by registered trial count.

749 US clinical trials · 275 currently recruiting · #4 of 28,963 conditions by registered trial count

Prostate Cancer: 749 US clinical trials tracked, 275 recruiting.

Prostate Cancer is the subject of 749 registered US clinical trials on ClinicalTrials.gov, 275 of them currently open to new participants. 75 are in Phase 3-4 (later-stage) and 344 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 53 of these trials.

Open enrollment, early-phase tilt

Prostate Cancer has 749 registered US clinical trials, 275 of them open to new participants right now, about 37% of the total.

275
recruiting participants now
37%
of trials open to enrollment
75
in Phase 3-4 (later-stage)
53
top sponsor: Memorial Sloan Kettering Cancer Center

Corpus placement: #4 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Prostate Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Prostate Cancer recruits in line with its size-band peers.

    275 of 749 indexed trials (36.7%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prostate Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 53 of 749 trials (7.1%). 283 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prostate Cancer enrolment sits around 82 participants.

    Median target enrolment is 82 among the 736 trials that report a genuine target (sentinel values excluded). 389 of those (52.9%) plan for fewer than 100 participants.

  4. Prostate Cancer research is mostly interventional.

    628 interventional and 121 observational studies make up this index (83.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1156Phase 2188Phase 362Phase 413

Open and recent trials

749 total, page 10 of 15

ACTIVE NOT RECRUITING Phase 1 12 participants

Long Acting Neuraxial Peri-prostatic Block in Cancer

Icahn School of Medicine at Mount Sinai

NCT06703437

ACTIVE NOT RECRUITING Early Phase 1 10 participants

Focal Laser Ablation of Prostate Cancer

Jonsson Comprehensive Cancer Center

NCT04305925

ACTIVE NOT RECRUITING Early Phase 1 9 participants

Androgen Receptor Signaling and Prostate-Specific Membrane Antigen Expression

Beth Israel Deaconess Medical Center

NCT05683964

ACTIVE NOT RECRUITING Phase 1 9 participants

Neo-DAB: Darolutamide and Abemaciclib in Prostate Cancer

Praful Ravi, MB BCHir, MRCP

NCT05617885

ACTIVE NOT RECRUITING Phase 1 6 participants

NeoAdjuvant Theranostic Lutetium Study: The Nautilus Trial

M.D. Anderson Cancer Center

NCT06066437

ACTIVE NOT RECRUITING Early Phase 1 1 participants

Magnetic Resonance (MR) Imaging With Hyperpolarized Bicarbonate (13C) to Measure Tissue pH in Prostate Cancer

Robert Flavell, MD, PhD

NCT05851365

COMPLETED Phase 3 35,533 participants

S0000 Selenium and Vitamin E in Preventing Prostate Cancer

SWOG Cancer Research Network

NCT00006392

COMPLETED 13,779 participants

A Study Using Available Data to Learn to What Extent Patients With Prostate Cancer Who Received Second Generation Androgen Receptor Inhibitors Took Their Medication as Prescribed or Stopped Taking Their Medication Completely

Bayer

NCT05202301

COMPLETED 10,805 participants

Continuation of Follow-up of DES-Exposed Cohorts

National Cancer Institute (NCI)

NCT00340600

COMPLETED 2,579 participants

Analyses of Human Samples Collected in Clinical Trials

National Cancer Institute (NCI)

NCT00339664

COMPLETED 2,472 participants

Cancer Prevention and Treatment Demonstration for Ethnic and Racial Minorities

M.D. Anderson Cancer Center

NCT00453661

COMPLETED Phase 3 2,028 participants

Radiation Therapy With or Without Antiandrogen Therapy in Treating Patients With Stage I or Stage II Prostate Cancer

Radiation Therapy Oncology Group

NCT00002597

COMPLETED NA 1,831 participants

Online Study of Colorectal Cancer and Prostate Cancer Screening Decision Making

University of North Carolina, Chapel Hill

NCT01558583

COMPLETED NA 1,800 participants

Multimedia Educational Program for Patients With Early-Stage Prostate Cancer or Breast Cancer

University of Colorado, Denver

NCT00830635

COMPLETED 1,556 participants

North Carolina Prostate Cancer Comparative Effectiveness & Survivorship Study (NC ProCESS)

UNC Lineberger Comprehensive Cancer Center

NCT02564120

COMPLETED Phase 3 1,534 participants

Radiation Therapy in Treating Patients With Stage II Prostate Cancer

Radiation Therapy Oncology Group

NCT00033631

COMPLETED Phase 3 1,494 participants

A Phase III Trial of ZD4054 (Zibotentan) (Endothelin A Antagonist) and Docetaxel in Metastatic Hormone Resistant Prostate Cancer

AstraZeneca

NCT00617669

COMPLETED Phase 3 1,313 participants

S1216, Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer

SWOG Cancer Research Network

NCT01809691

COMPLETED Phase 3 1,245 participants

A Study of Tasquinimod in Men With Metastatic Castrate Resistant Prostate Cancer

Active Biotech AB

NCT01234311

COMPLETED Phase 3 1,200 participants

Toremifene Citrate for Prevention of Bone Fractures in Men With Prostate Cancer on Androgen Deprivation Therapy

GTx

NCT00129142

COMPLETED Phase 3 1,088 participants

Abiraterone Acetate in Asymptomatic or Mildly Symptomatic Patients With Metastatic Castration-Resistant Prostate Cancer

Janssen Research & Development

NCT00887198

COMPLETED Phase 1 1,084 participants

Radiation Therapy in Treating Patients With Stage II or Stage III Prostate Cancer

Radiation Therapy Oncology Group

NCT00002602

COMPLETED Phase 3 1,028 participants

Study of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100

Exelixis

NCT01605227

COMPLETED Phase 3 1,022 participants

Comparison of Docetaxel/Prednisone to Docetaxel/Prednisone in Combination With OGX-011 in Men With Prostate Cancer

Achieve Life Sciences

NCT01188187

COMPLETED Phase 3 983 participants

S9921, Hormone Therapy With or Without Mitoxantrone and Prednisone in Patients Who Have Undergone Radical Prostatectomy for Prostate Cancer

SWOG Cancer Research Network

NCT00004124

COMPLETED Phase 3 861 participants

Study of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer

Endocyte

NCT03511664

COMPLETED Phase 3 837 participants

Phase 3 Study of Immunotherapy to Treat Advanced Prostate Cancer

Bristol-Myers Squibb

NCT01057810

COMPLETED 774 participants

Clinical Outcomes in Men With Prostate Cancer Who Selected Active Surveillance Using Prolaris® Testing

Myriad Genetic Laboratories

NCT03511235

COMPLETED Phase 3 770 participants

S9916, Combination Therapy in Treating Patients With Advanced Prostate Cancer That Has Not Responded to Hormone Therapy

SWOG Cancer Research Network

NCT00004001

COMPLETED NA 641 participants

Shared Decision Making: Prostate Cancer Screening

Lisa Richarson

NCT00207649

COMPLETED Phase 3 588 participants

Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer

Radiation Therapy Oncology Group

NCT00063882

COMPLETED NA 556 participants

Optimizing Veteran-Centered Prostate Cancer Survivorship Care

VA Office of Research and Development

NCT01900561

COMPLETED Phase 2 554 participants

CD-ROM Intervention for Prostate Cancer Screening

Centers for Disease Control and Prevention

NCT00164437

COMPLETED 500 participants

Quality of Life in Patients Undergoing Surgery or Brachytherapy for Stage II Prostate Cancer

Alliance for Clinical Trials in Oncology

NCT00052481

COMPLETED NA 498 participants

Personal Patient Profile Prostate (P4) Randomized, Multisite Trial

Dana-Farber Cancer Institute

NCT00692653

COMPLETED NA 483 participants

Intimacy-Enhancing Couples' Intervention for Localized Prostate Cancer

Rutgers, The State University of New Jersey

NCT01982058

COMPLETED NA 480 participants

Group Therapy Compared With Educational Materials in Patients With Prostate Cancer

Gary Morrow

NCT00002848

COMPLETED Phase 3 396 participants

Low Dose Supplemental External Radiation With Pd-103 Versus Pd-103 Alone for Prostate Cancer

Schiffler Cancer Center

NCT00241384

COMPLETED NA 392 participants

Personal Patient Profile - Prostate (P3P) II: Effectiveness-Implementation Trial in Diverse Health Care Networks

Dana-Farber Cancer Institute

NCT01844999

COMPLETED Phase 3 390 participants

Low, Intermediate, or High Dose Suramin in Treating Patients With Hormone-Refractory Prostate Cancer

National Cancer Institute (NCI)

NCT00002723

COMPLETED Phase 3 387 participants

Randomized Study to Evaluate MACE in Patients With Prostate Cancer Treated With Relugolix or Leuprolide Acetate

Sumitomo Pharma America

NCT05605964

COMPLETED Phase 3 386 participants

A Long-term Extension Study Evaluating a One-Month Dosing Regimen of Degarelix in Prostate Cancer Requiring Androgen Ablation Therapy

Ferring Pharmaceuticals

NCT00451958

COMPLETED Phase 3 384 participants

Extension Study to Evaluate Long Term Safety of Denosumab in Subjects Undergoing ADT for Non-Metastatic Prostate Cancer

Amgen

NCT00838201

COMPLETED 374 participants

Experiment to Assess Preferences for Novel Hormonal Therapy and Androgen-deprivation Therapy in Prostate Cancer Patients

Astellas Pharma Global Development

NCT06500741

COMPLETED NA 356 participants

Genomics in Michigan Impacting Observation or Radiation

University of Michigan Rogel Cancer Center

NCT02783950

COMPLETED Phase 2 351 participants

A Study of Nivolumab Plus Ipilimumab, Ipilimumab Alone, or Cabazitaxel in Men With Metastatic Castration-Resistant Prostate Cancer (CheckMate 650)

Bristol-Myers Squibb

NCT02985957

COMPLETED Phase 1 350 participants

Buffered Lidocaine for Reducing Pain in Patients Undergoing Prostate Biopsy, BURN Trial

University of Washington

NCT06661902

COMPLETED Phase 1 347 participants

Phase I/II Hypofractionated Radiotherapy for Prostate Cancer

University of Wisconsin, Madison

NCT00214097

COMPLETED NA 340 participants

Evaluation of the Efficacy of National Cancer Institute's Facing Forward Booklet in the Cancer Community Setting

Fox Chase Cancer Center

NCT01440855

COMPLETED NA 325 participants

Collection of Patient-Reported Symptoms and Performance Status Via the Internet

Alliance for Clinical Trials in Oncology

NCT00417040

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Phase Distribution

PhaseTrial count
Phase 1 156
Phase 2 188
Phase 3 62
Phase 4 13

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Prostate Cancer right now

275 recruiting of 749 indexed (37% open).

Phase mix: 75 late (III/IV) vs 344 early (I/II) (early-phase heavy).

Top sponsor: Memorial Sloan Kettering Cancer Center (53 trials), 9 others listed. 50 shown below, recruiting first. #4 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Prostate Cancer?

PlainTrial tracks 749 US clinical trials for Prostate Cancer, of which 275 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Prostate Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.