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NCT00004001 · ClinicalTrials.gov registry record · Phase 3
S9916, Combination Therapy in Treating Patients With Advanced Prostate Cancer That Has Not Responded to Hormone Therapy
A Phase 3 study of Prostate Cancer, sponsored by SWOG Cancer Research Network.
- Completed
- Registry status
- Phase 3
- Development phase
- 770
- Enrollment target
- 16
- Study locations
NCT00004001: Completed Phase 3 study of Prostate Cancer, sponsored by SWOG Cancer Research Network.
NCT00004001 is a Phase 3 study of Prostate Cancer that has completed, run by SWOG Cancer Research Network. The registered enrollment target is 770 participants, above the 607-participant average among 735 other Prostate Cancer trials with a reported enrollment target (27% higher). The trial reports 16 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00004001, a Phase 3 study of Prostate Cancer, has completed, sponsored by SWOG Cancer Research Network.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 770 participants
- Enrollment target
- 16
- Study locations
Study Summary
RATIONALE: Drugs used in chemotherapy and hormone therapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving drugs in different ways may kill more tumor cells. It is not yet known whether estramustine plus docetaxel is more effective than mitoxantrone plus prednisone for prostate cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of estramustine plus docetaxel with that of mitoxantrone plus prednisone in treating patients who have stage IV prostate cancer that has not responded to hormone therapy.
Primary Outcome
Measured from date of registration to date of death due to any cause
Conditions Studied
Interventions
- DRUG prednisone
- DRUG docetaxel
- DRUG mitoxantrone
- DRUG estramustine
Study Locations (16)
Iowa
- CCOP - Cedar Rapids Oncology Project - Cedar Rapids
- CCOP - Iowa Oncology Research Association - Des Moines
- Siouxland Hematology-Oncology - Sioux City
North Dakota
- Medcenter One Health System - Bismarck
- CCOP - Merit Care Hospital - Fargo
- Altru Health System - Grand Forks
Illinois
- CCOP - Illinois Oncology Research Association - Peoria
- CCOP - Carle Cancer Center - Urbana
Minnesota
- Mayo Clinic Cancer Center - Rochester
- CentraCare Health Plaza - Saint Cloud
South Dakota
- Rapid City Regional Hospital - Rapid City
- CCOP - Sioux Community Cancer Consortium - Sioux Falls
Arizona
- CCOP - Scottsdale Oncology Program - Scottsdale
Florida
- Mayo Clinic - Jacksonville
Nebraska
- CCOP - Missouri Valley Cancer Consortium - Omaha
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 770 participants |
| Start Date | 1999-10 |
| Est. Completion | 2007-01 |
| Phase | Phase 3 |
What the finished NCT00004001 record still lists
NCT00004001 is an interventional study that assigns participants to a tested intervention. The registered 770 participants enrollment target is mid-sized for trials with a published cap, above the 607-participant average among 735 other Prostate Cancer trials with a reported enrollment target (27% higher).
The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 4 interventions - of which prednisone is the first listed.
NCT00004001 lists 16 locations in 9 states (Iowa, North Dakota, Illinois).
Frequently Asked Questions
What is clinical trial NCT00004001 about?
NCT00004001 is a clinical study titled "S9916, Combination Therapy in Treating Patients With Advanced Prostate Cancer That Has Not Responded to Hormone Therapy". RATIONALE: Drugs used in chemotherapy and hormone therapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving drugs in different ways may kill more tumor cells. It is not yet known whether estramustine plus docetaxel is more effec...
What is the current status of trial NCT00004001?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 770 participants. The study started on 1999-10. Estimated completion is 2007-01.
What conditions does trial NCT00004001 study?
This clinical trial studies the following conditions: Prostate Cancer.
What interventions are being tested in trial NCT00004001?
The interventions under investigation include: prednisone (DRUG), docetaxel (DRUG), mitoxantrone (DRUG), estramustine (DRUG).
Who is sponsoring clinical trial NCT00004001?
This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00004001 being conducted?
This trial has 16 study locations across Arizona, Florida, Illinois, Iowa, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Prostate Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00004001's enrollment target sits among peer trials
770 83rd of 735 higher than 653 of 735 other Prostate Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Prostate Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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