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NCT00129142 · ClinicalTrials.gov registry record · Phase 3
Toremifene Citrate for Prevention of Bone Fractures in Men With Prostate Cancer on Androgen Deprivation Therapy
A Phase 3 study of Prostate Cancer and Osteoporosis, sponsored by GTx.
- Completed
- Registry status
- Phase 3
- Development phase
- 1,200
- Enrollment target
- 20
- Study locations
NCT00129142: Completed Phase 3 study of Prostate Cancer and Osteoporosis, sponsored by GTx.
NCT00129142 is a Phase 3 study of Prostate Cancer and Osteoporosis that has completed, run by GTx. The registered enrollment target is 1,200 participants, above the 607-participant average among 735 other Prostate Cancer trials with a reported enrollment target (98% higher). The trial reports 20 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00129142, a Phase 3 study of Prostate Cancer and Osteoporosis, has completed, sponsored by GTx.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 1,200 participants
- Enrollment target
- 20
- Study locations
Study Summary
Androgen deprivation therapy (ADT) treatment for prostate cancer decreases the natural hormone called testosterone. This type of therapy is very effective for the treatment of prostate cancer. However, one of the side effects is bone loss or thinning of the bones that can lead to osteoporosis and an increased risk of bone fractures (breaking of the bones). The purpose of the study is to determine whether or not the addition of toremifene citrate (the study drug) to therapy can prevent or decrease the number of bone fractures and to evaluate its impact on side effects associated with testosterone reduction therapy.
Conditions Studied
Interventions
- DRUG Toremifene Citrate
Study Locations (20)
California
- Advanced Urology Medical Center Clinical Trials - Anaheim
- Urological Sciences Research Foudation - Culver City
- Urological Associates of Central CA - Fresno
- Center of Urologic Research - La Mesa
- South Orange County Medical Research Center - Laguna Woods
- Palo Alto VA - Palo Alto
- San Bernadino Urological Associates - San Bernadino
- Urological Physicians of San Diego - San Diego
- Veterans Medical Research Foundation - San Diego
- Pacific Clinical Research - Santa Monica
- West Coast Clinical Research - Tarzana
- Western Clinical Research, Inc. - Torrance
Connecticut
- Urologic Center - New Haven
- Urological Associates of Bridgeport - Trumball
- Connecticut Clinical Research - Waterbury
Alabama
- Urology Centers of Alabama - Homewood
- Coastal Clinical Research - Mobile
Colorado
- Urology Associates - Denver
- Western Urological Research - Wheat Ridge
Arkansas
- Arkansas Urology - Little Rock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,200 participants |
| Start Date | 2003-10 |
| Est. Completion | 2007-11 |
| Phase | Phase 3 |
What the finished NCT00129142 record still lists
NCT00129142 is an interventional study that assigns participants to a tested intervention. Its 1,200 participants enrollment target places it among the larger protocols in the corpus, above the 607-participant average among 735 other Prostate Cancer trials with a reported enrollment target (98% higher).
The record links to 3 conditions, with Prostate Cancer appearing as the primary indexed condition, and to 1 intervention - of which Toremifene Citrate is the first listed.
NCT00129142 names 20 study sites across 5 states, led by California, Connecticut, Alabama.
Frequently Asked Questions
What is clinical trial NCT00129142 about?
NCT00129142 is a clinical study titled "Toremifene Citrate for Prevention of Bone Fractures in Men With Prostate Cancer on Androgen Deprivation Therapy". Androgen deprivation therapy (ADT) treatment for prostate cancer decreases the natural hormone called testosterone. This type of therapy is very effective for the treatment of prostate cancer. However, one of the side effects is bone loss or thinning of the bones that can lead to osteoporosis and an...
What is the current status of trial NCT00129142?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,200 participants. The study started on 2003-10. Estimated completion is 2007-11.
What conditions does trial NCT00129142 study?
This clinical trial studies the following conditions: Prostate Cancer, Osteoporosis, Fractures.
What interventions are being tested in trial NCT00129142?
The interventions under investigation include: Toremifene Citrate (DRUG).
Who is sponsoring clinical trial NCT00129142?
This trial is sponsored by GTx, which has 15 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00129142 being conducted?
This trial has 20 study locations across Alabama, Arkansas, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Prostate Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00129142's enrollment target sits among peer trials
1,200 43rd of 735 higher than 693 of 735 other Prostate Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Prostate Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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