Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00033631 · ClinicalTrials.gov registry record · Phase 3

Radiation Therapy in Treating Patients With Stage II Prostate Cancer

A Phase 3 study of Prostate Cancer, sponsored by Radiation Therapy Oncology Group.

Completed
Registry status
Phase 3
Development phase
1,534
Enrollment target
20
Study locations

NCT00033631: Completed Phase 3 study of Prostate Cancer, sponsored by Radiation Therapy Oncology Group.

NCT00033631 is a Phase 3 study of Prostate Cancer that has completed, run by Radiation Therapy Oncology Group. The registered enrollment target is 1,534 participants, above the 606-participant average among 735 other Prostate Cancer trials with a reported enrollment target (153% higher). The trial reports 20 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00033631, a Phase 3 study of Prostate Cancer, has completed, sponsored by Radiation Therapy Oncology Group.

COMPLETED
Registry status
Phase 3
Development phase
1,534 participants
Enrollment target
20
Study locations

Study Summary

RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. It is not yet known which dose of radiation therapy is more effective in treating stage II prostate cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of two different doses of specialized radiation therapy in treating patients who have stage II prostate cancer.

Primary Outcome

Survival time is defined as time from randomization to the date of death from any cause and is estimated by the Kaplan-Meier Method. Patients last know to be alive are censored at date of last contact.

Conditions Studied

Interventions

  • RADIATION 70.2 Gy 3D-CRT/IMRT
  • RADIATION 79.2 Gy 3D-CRT/IMRT

Study Locations (20)

Kansas

  • Providence Medical Center - Kansas City
  • Lawrence Memorial Hospital - Lawrence
  • Menorah Medical Center - Overland Park
  • Johnson County Radiation Therapy - Overland Park
  • Shawnee Mission Medical Center - Shawnee Mission

Michigan

  • Veterans Affairs Medical Center - Ann Arbor - Ann Arbor
  • University of Michigan Comprehensive Cancer Center - Ann Arbor
  • Foote Memorial Hospital - Jackson
  • West Michigan Cancer Center - Kalamazoo

California

  • Veterans Affairs Medical Center - Long Beach - Long Beach
  • Radiological Associates of Sacramento Medical Group, Incorporated - Sacramento
  • UCSF Helen Diller Family Comprehensive Cancer Center - San Francisco

Indiana

  • Oncology Center at Saint Margaret Mercy Healthcare Center - Hammond
  • Cancer Center at Ball Memorial Hospital - Muncie

Maryland

  • Greenebaum Cancer Center at University of Maryland Medical Center - Baltimore
  • Central Maryland Oncology Center - Columbia

District of Columbia

  • Washington Cancer Institute at Washington Hospital Center - Washington D.C.

Florida

  • Bay Medical - Panama City

Illinois

  • Methodist Medical Center of Illinois - Peoria

Trial Details

FieldValue
Enrollment Target 1,534 participants
Start Date 2002-03
Est. Completion 2022-12-22
Phase Phase 3
Radiation Therapy Oncology Group

144 total trials

What the finished NCT00033631 record still lists

NCT00033631 is an interventional study that assigns participants to a tested intervention. Its 1,534 participants enrollment target places it among the larger protocols in the corpus, above the 606-participant average among 735 other Prostate Cancer trials with a reported enrollment target (153% higher).

The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 2 interventions - of which 70.2 Gy 3D-CRT/IMRT is the first listed.

NCT00033631 names 20 study sites across 9 states, led by Kansas, Michigan, California.

Frequently Asked Questions

What is clinical trial NCT00033631 about?

NCT00033631 is a clinical study titled "Radiation Therapy in Treating Patients With Stage II Prostate Cancer". RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. It is not yet known which dose of radiation therapy is more effective in treating stage II prostate cancer. PURPOSE: Randomized pha...

What is the current status of trial NCT00033631?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,534 participants. The study started on 2002-03. Estimated completion is 2022-12-22.

What conditions does trial NCT00033631 study?

This clinical trial studies the following conditions: Prostate Cancer.

What interventions are being tested in trial NCT00033631?

The interventions under investigation include: 70.2 Gy 3D-CRT/IMRT (RADIATION), 79.2 Gy 3D-CRT/IMRT (RADIATION).

Who is sponsoring clinical trial NCT00033631?

This trial is sponsored by Radiation Therapy Oncology Group, which has 144 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00033631 being conducted?

This trial has 20 study locations across California, District of Columbia, Florida, Illinois, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Prostate Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00033631's enrollment target sits among peer trials

1,534 34th of 735 higher than 702 of 735 other Prostate Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Prostate Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT06842875 · 1,536 participants · NA

    Rhode Island - Statewide Postpartum Hypertension Remote Surveillance

  • NCT06393374 · 1,530 participants · Phase 3

    Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

  • NCT07114510 · 1,530 participants · NA

    Optimal Ventilation for Cardiac Arrest

  • NCT06623097 · 1,528 participants · NA

    Exercise and Nutrition for Older Cancer Survivors and Their Support Person: The Vitality Study

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00033631, the US trial registry maintained by the National Library of Medicine. NCT00033631 (large enrollment · wide site footprint · completed) retrieved and formatted by PlainTrial, see methodology.