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COMPLETED Phase 3

Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer

NCT00063882 · View on ClinicalTrials.gov ↗

Study Summary

RATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells. Interstitial brachytherapy uses radioactive material placed directly into or near a tumor to kill tumor cells. Combining interstitial brachytherapy with external-beam radiation therapy may kill more tumor cells. It is not yet known whether interstitial brachytherapy is more effective with or without external-beam radiation therapy in treating prostate cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of interstitial brachytherapy with or without external-beam radiation therapy in treating patients who have prostate cancer.

Conditions Studied

Interventions

  • RADIATION External Beam Radiation Therapy
  • RADIATION Brachytherapy (100/110)
  • RADIATION Brachytherapy (125/145)

Study Locations (20)

California

  • Auburn Radiation Oncology — Auburn
  • Alta Bates Summit Comprehensive Cancer Center — Berkeley
  • Peninsula Medical Center — Burlingame
  • Radiation Oncology Centers - Cameron Park — Cameron Park
  • Mercy Cancer Center at Mercy San Juan Medical Center — Carmichael
  • East Bay Radiation Oncology Center — Castro Valley
  • Valley Medical Oncology Consultants - Castro Valley — Castro Valley
  • Valley Medical Oncology — Fremont
  • California Cancer Center - Woodward Park Office — Fresno
  • Kaiser Permanente Medical Center - Hayward — Hayward
  • Contra Costa Regional Medical Center — Martinez
  • El Camino Hospital Cancer Center — Mountain View
  • Sutter Health - Western Division Cancer Research Group — Novato
  • Alta Bates Summit Medical Center - Summit Campus — Oakland
  • Bay Area Breast Surgeons, Incorporated — Oakland
  • CCOP - Bay Area Tumor Institute — Oakland
  • Larry G Strieff MD Medical Corporation — Oakland
  • Tom K Lee, Incorporated — Oakland
  • Kaiser Permanente - Division of Research - Oakland — Oakland

Arizona

  • Arizona Oncology Services Foundation — Phoenix

Trial Details

FieldValue
Enrollment Target 588 participants
Start Date 2003-06
Est. Completion 2022-12-22
Phase Phase 3

Sponsor

Radiation Therapy Oncology Group

37 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00063882

The ClinicalTrials.gov registry entry for NCT00063882 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 588 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Radiation Therapy Oncology Group, which has 37 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 3 interventions — of which External Beam Radiation Therapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00063882 reports 20 study locations spanning 2 distinct geographic areas — top geographies include California, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00063882 about?

NCT00063882 is a clinical study titled "Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer". RATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells. Interstitial brachytherapy uses radioactive material placed directly into or near a tumor to kill tumor cells. Combining interstitial brachytherapy with external-beam radiation therapy may kill more tumor c...

What is the current status of trial NCT00063882?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 588 participants. The study started on 2003-06. Estimated completion is 2022-12-22.

What conditions does trial NCT00063882 study?

This clinical trial studies the following conditions: Prostate Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00063882?

The interventions under investigation include: External Beam Radiation Therapy (RADIATION), Brachytherapy (100/110) (RADIATION), Brachytherapy (125/145) (RADIATION). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00063882?

This trial is sponsored by Radiation Therapy Oncology Group, which has 37 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00063882 being conducted?

This trial has 20 study locations across Arizona, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial