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NCT00063882 · ClinicalTrials.gov registry record · Phase 3
Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer
A Phase 3 study of Prostate Cancer, sponsored by Radiation Therapy Oncology Group.
- Completed
- Registry status
- Phase 3
- Development phase
- 588
- Enrollment target
- 20
- Study locations
NCT00063882: Completed Phase 3 study of Prostate Cancer, sponsored by Radiation Therapy Oncology Group.
NCT00063882 is a Phase 3 study of Prostate Cancer that has completed, run by Radiation Therapy Oncology Group. The registered enrollment target is 588 participants, roughly in line with the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target. The trial reports 20 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00063882, a Phase 3 study of Prostate Cancer, has completed, sponsored by Radiation Therapy Oncology Group.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 588 participants
- Enrollment target
- 20
- Study locations
Study Summary
RATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells. Interstitial brachytherapy uses radioactive material placed directly into or near a tumor to kill tumor cells. Combining interstitial brachytherapy with external-beam radiation therapy may kill more tumor cells. It is not yet known whether interstitial brachytherapy is more effective with or without external-beam radiation therapy in treating prostate cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of interstitial brachytherapy with or without external-beam radiation therapy in treating patients who have prostate cancer.
Primary Outcome
A Freedom from Progression (FFP) failure includes biochemical failure, local failure, distant failure, or death due to any cause. Patients who are failure free with less than 5 years of follow-up or who receive any secondary salvage therapy are censored. Freedom from Progression rates are estimated using the Kaplan-Meier method.
Conditions Studied
Interventions
- RADIATION External Beam Radiation Therapy
- RADIATION Brachytherapy (100/110)
- RADIATION Brachytherapy (125/145)
Study Locations (20)
California
- Auburn Radiation Oncology - Auburn
- Alta Bates Summit Comprehensive Cancer Center - Berkeley
- Peninsula Medical Center - Burlingame
- Radiation Oncology Centers - Cameron Park - Cameron Park
- Mercy Cancer Center at Mercy San Juan Medical Center - Carmichael
- East Bay Radiation Oncology Center - Castro Valley
- Valley Medical Oncology Consultants - Castro Valley - Castro Valley
- Valley Medical Oncology - Fremont
- California Cancer Center - Woodward Park Office - Fresno
- Kaiser Permanente Medical Center - Hayward - Hayward
- Contra Costa Regional Medical Center - Martinez
- El Camino Hospital Cancer Center - Mountain View
- Sutter Health - Western Division Cancer Research Group - Novato
- Alta Bates Summit Medical Center - Summit Campus - Oakland
- Bay Area Breast Surgeons, Incorporated - Oakland
- CCOP - Bay Area Tumor Institute - Oakland
- Larry G Strieff MD Medical Corporation - Oakland
- Tom K Lee, Incorporated - Oakland
- Kaiser Permanente - Division of Research - Oakland - Oakland
Arizona
- Arizona Oncology Services Foundation - Phoenix
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 588 participants |
| Start Date | 2003-06 |
| Est. Completion | 2022-12-22 |
| Phase | Phase 3 |
What the finished NCT00063882 record still lists
NCT00063882 is an interventional study that assigns participants to a tested intervention. The registered 588 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target.
The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 3 interventions - of which External Beam Radiation Therapy is the first listed.
NCT00063882 names 20 study sites across 2 states, led by California, Arizona.
Frequently Asked Questions
What is clinical trial NCT00063882 about?
NCT00063882 is a clinical study titled "Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer". RATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells. Interstitial brachytherapy uses radioactive material placed directly into or near a tumor to kill tumor cells. Combining interstitial brachytherapy with external-beam radiation therapy may kill more tumor c...
What is the current status of trial NCT00063882?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 588 participants. The study started on 2003-06. Estimated completion is 2022-12-22.
What conditions does trial NCT00063882 study?
This clinical trial studies the following conditions: Prostate Cancer.
What interventions are being tested in trial NCT00063882?
The interventions under investigation include: External Beam Radiation Therapy (RADIATION), Brachytherapy (100/110) (RADIATION), Brachytherapy (125/145) (RADIATION).
Who is sponsoring clinical trial NCT00063882?
This trial is sponsored by Radiation Therapy Oncology Group, which has 144 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00063882 being conducted?
This trial has 20 study locations across Arizona, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Prostate Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00063882's enrollment target sits among peer trials
588 99th of 735 higher than 637 of 735 other Prostate Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Prostate Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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