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NCT06661902 · ClinicalTrials.gov registry record · Phase 1

Buffered Lidocaine for Reducing Pain in Patients Undergoing Prostate Biopsy, BURN Trial

A Phase 1 study of Prostate Cancer, sponsored by University of Washington.

Completed
Registry status
Phase 1
Development phase
350
Enrollment target
1
Study location

NCT06661902 is a Phase 1 study of Prostate Cancer that has completed, run by University of Washington. The registered enrollment target is 350 participants, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (42% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06661902, a Phase 1 study of Prostate Cancer, has completed, sponsored by University of Washington.

COMPLETED
Registry status
Phase 1
Development phase
350 participants
Enrollment target
1
Study location

Study Summary

This phase I/II trial examines if buffered lidocaine reduces the pain that patients may experience during prostate biopsy. Prostate biopsies are typically performed awake, in the office, with only local anesthetic. As a result, many patients note considerable pain during these procedures. Local anesthetics such as lidocaine are typically acidic, which is thought to cause pain and burning during infiltration (injection). As a result, buffered local anesthetic has become the standard of care (SOC) in multiple specialties using awake local anesthetic. However, it has not been explored during prostate biopsies. Adminstering buffered lidocaine may reduce pain in patients undergoing prostate biopsy.

Conditions Studied

Interventions

  • OTHER Questionnaire Administration
  • PROCEDURE Biopsy of Prostate
  • DRUG Lidocaine
  • DRUG Buffered Lidocaine (1% Lidocaine + 8.4% Sodium Bicarbonate, in a 3:1 ratio)

Study Locations (1)

Washington

  • Fred Hutch/University of Washington Cancer Consortium - Seattle

Trial Details

FieldValue
Enrollment Target 350 participants
Start Date 2025-01-09
Est. Completion 2026-01-27
Phase Phase 1

Sponsor

University of Washington

1,048 total trials

What the Registry Record Tells You About NCT06661902

The ClinicalTrials.gov registry entry for NCT06661902 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 350 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (42% lower). The listed sponsor is University of Washington, which has 1,048 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 4 interventions - of which Questionnaire Administration is the first listed.

NCT06661902 reports 1 study location spanning 1 distinct geographic area - top geographies include Washington.

Frequently Asked Questions

What is clinical trial NCT06661902 about?

NCT06661902 is a clinical study titled "Buffered Lidocaine for Reducing Pain in Patients Undergoing Prostate Biopsy, BURN Trial". This phase I/II trial examines if buffered lidocaine reduces the pain that patients may experience during prostate biopsy. Prostate biopsies are typically performed awake, in the office, with only local anesthetic. As a result, many patients note considerable pain during these procedures. Local anes...

What is the current status of trial NCT06661902?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 350 participants. The study started on 2025-01-09. Estimated completion is 2026-01-27.

What conditions does trial NCT06661902 study?

This clinical trial studies the following conditions: Prostate Cancer.

What interventions are being tested in trial NCT06661902?

The interventions under investigation include: Questionnaire Administration (OTHER), Biopsy of Prostate (PROCEDURE), Lidocaine (DRUG), Buffered Lidocaine (1% Lidocaine + 8.4% Sodium Bicarbonate, in a 3:1 ratio) (DRUG).

Who is sponsoring clinical trial NCT06661902?

This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06661902 being conducted?

This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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