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PreDiabetes: full-pipeline trial registry
69 of 150 indexed PreDiabetes trials are currently recruiting.
Corpus placement: #78 of 28,707 conditions by registered trial count.
150 US clinical trials · 69 currently recruiting · #78 of 28,707 conditions by registered trial count
PreDiabetes: 150 US clinical trials tracked, 69 recruiting.
PreDiabetes is the subject of 150 registered US clinical trials on ClinicalTrials.gov, 69 of them currently open to new participants. 7 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Ohio State University, running 5 of these trials.
Enrollment posture brief
Registry condition prediabetes
OPEN 69 | RECR 46% | LATE 7 | EARLY 9 | RANK #78 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Chronic Pain (46% recruiting · 302 trials)
PreDiabetes lists 69 open slots (46% of 150 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for PreDiabetes on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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PreDiabetes is recruiting above its size-band peers.
69 of 150 indexed trials (46%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of PreDiabetes trials is spread across many organizations.
Ohio State University accounts for 5 of 150 trials (3.3%). 97 distinct sponsors appear on at least one study for this condition label.
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Typical PreDiabetes enrolment sits around 80 participants.
Median target enrolment is 80 among the 150 trials that report a genuine target (sentinel values excluded). 87 of those (58%) plan for fewer than 100 participants.
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PreDiabetes research is mostly interventional.
135 interventional and 15 observational studies make up this index (90% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
150 total, page 3 of 3
Habit Building Software Application to Increase Engagement of Vulnerable Populations in the National Diabetes Prevention Program (NDPP) Lifestyle Change Program (LCP)
The Institute for Iterative Thinking
NCT06656273
Effectiveness Study of Community-Based, Peer-Led Education on Weight Loss and Diabetes
Icahn School of Medicine at Mount Sinai
NCT01004848
Power-Up: An Effectiveness Trial of the Diabetes Prevention Program
Albert Einstein College of Medicine
NCT04104243
Exercise Dose-Response Effects in Prediabetes
Duke University
NCT00962962
Assessing the Effectiveness of a Weight Watchers-based Lifestyle Intervention for the Primary Prevention of Type 2 Diabetes
Indiana University
NCT02000024
A Study of the Function of Hormones Present In Taste Buds
National Institute on Aging (NIA)
NCT00233298
Patient-centered Goal Setting in the National Diabetes Prevention Program
Denver Health and Hospital Authority
NCT05559515
Glucose Risk Assessment in Employer Populations
DexCom
NCT04529824
Text Messaging for Weight Loss
Denver Health and Hospital Authority
NCT02063048
The Effect of Real Time Continuous Glucose Monitoring in Subjects With Pre-diabetes
Walter Reed National Military Medical Center
NCT01741467
Trial of an Herb and Mineral Combination Product on Fasting Glucose in Adults at Risk for Developing Diabetes
NewChapter
NCT02146157
Healthy Body Healthy Souls in the Marshallese Population
University of Arkansas
NCT03377244
Balanced (Egg) Protein During Obesity Reduction: Differential Responses of Insulin Resistance by Race
Duke University
NCT03771261
Community-based Adolescent Diabetes Prevention Program
Icahn School of Medicine at Mount Sinai
NCT02458131
Dietary Exchanges With Avocado and Mango in Pre-diabetes
Clinical Nutrition Research Center, Illinois Institute of Technology
NCT05353790
T-UP: Engaging Vulnerable Students in Diabetes Prevention
University of California, Los Angeles
NCT06385015
Effects of a Dietary Supplement Containing L-Arabinose and Trivalent Patented Food-source of Chromium on Blood Glucose and Insulin
Integrative Health Technologies
NCT01107431
Food as Medicine: A Quasi-Randomized Control Trial of Healthy Foods for Chronic Disease Management
Cleveland Clinic Akron General
NCT05174078
Fit and Trim for Diabetes Prevention
University of California, San Francisco
NCT02278939
Skeletal Muscle Diacylglycerol and Sphingolipids - Impact of Localization and Species on Insulin Resistance in Humans
University of Colorado, Denver
NCT03077360
Evaluation of Empagliflozin vs Standard Care in Veterans With Prediabetes
Charles George VA Medical Center
NCT06828731
Effect of Dietary Glycemic Index on Beta-cell Function
Seattle Institute for Biomedical and Clinical Research
NCT01386645
Healthy Liver - Healthy Brain
University of Texas at Austin
NCT05216796
Diabetes Risk Education and Communication Trial
Northwestern University
NCT03283657
Impact of No-carrageenan Diet on Glucose Tolerance in Prediabetes
University of Illinois at Chicago
NCT02720393
Models of Nutrition From Continuous Glucose Monitors
Texas A&M University
NCT04991142
Beneficial Effect of Salicylates: Insulin Action, Secretion or Clearance?
Stanford University
NCT02007577
Continuous Glucose Monitors (CGM) for Type 2 Diabetes (T2D) Risk Evaluation
Mary Ellen Vajravelu, MD
NCT05404711
CGM Plus GEM in Prediabetes
University of Colorado, Denver
NCT05580978
Family Diabetes Prevention Program Pilot Study
Johns Hopkins University
NCT05358444
Effects of Fos Biomedical Device on Diabetes Risk Factors and Sleep Quality in Adults at Risk for Type 2 Diabetes
Griffin Hospital
NCT05628597
Feasibility and Preliminary Effects of Fasting-Mimicking Diet in Asian Americans With Prediabetes
University of California, Irvine
NCT06518798
A Mindfulness-based Intervention for Adolescents With Prediabetes or Type 2 Diabetes
Indiana University
NCT07270900
Diabetes Prevention Program Pilot
Penn State University
NCT04651816
Time Restricted Eating on Cancer Risk
Medical University of South Carolina
NCT05038137
Women's Lifestyle Balance Study
University of California, San Francisco
NCT03184337
Continuous Glucose Monitoring in Prediabetes
University of Southern California
NCT06472297
Regulation of Postprandial Nitric Oxide Bioavailability and Vascular Function By Dairy Fat
Ohio State University
NCT02482610
Incretins in Impaired Fasting Glucose
Mayo Clinic
NCT00364377
Maternal Health Diabetes Prevention Study
Tulane University
NCT05343494
Cardioprotective Activities Of Whole Eggs On Vascular Endothelial Function In Prediabetic Adults
Ohio State University
NCT02364570
A Study to Evaluate the Effects of Vildagliptin on the Insulin Response to Glucose in Subjects With Pre-diabetes
Novartis
NCT00312130
WorkWell: Work-based Activity and Metabolic Health
Arizona State University
NCT04269070
The Role of Cholinergic Signaling for Mediating the Effects of GIP and/or Xenin-25 on Insulin Secretion
Washington University School of Medicine
NCT01951729
Continuous Glucose Monitoring (CGM) With a Low Carbohydrate Diet to Reduce Weight in Patients With Pre-Diabetes
University of Michigan
NCT03695913
Effect of Food Order on Postprandial Glucose Excursions in Pre-Diabetes
Weill Medical College of Cornell University
NCT03536364
Evaluating the Acute Glycemic Response to Different Strategies of Breaking Up Sedentary Time
Arizona State University
NCT04144920
Morning Light Treatment to Improve Glucose Metabolism
Northwestern University
NCT03188263
Behavior Change Intervention for Cardiovascular Risk Reduction Among People Experiencing Homelessness
Katherine Vickery
NCT06025721
Comparison of Time-Restricted Feeding Versus Grazing
Pennington Biomedical Research Center
NCT01895179
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 5 |
| Phase 3 | 1 |
| Phase 4 | 6 |
Top Sponsors
Named interventions
Most-linked intervention names on PreDiabetes records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on PreDiabetes trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this PreDiabetes page
150 registered trials, 69 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 69 PreDiabetes trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Ohio State University sponsors the most PreDiabetes trials on record, review their full trial history before evaluating a specific study. See Ohio State University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This PreDiabetes condition card totals 150 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.