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NCT05023993 · ClinicalTrials.gov registry record · NA
The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer
A NA study of Malignant Solid Neoplasm and PreDiabetes, sponsored by City of Hope Medical Center.
- Active
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05023993: Active NA study of Malignant Solid Neoplasm and PreDiabetes, sponsored by City of Hope Medical Center.
NCT05023993 is a NA study of Malignant Solid Neoplasm and PreDiabetes that is active but no longer recruiting, run by City of Hope Medical Center. The registered enrollment target is 20 participants, below the 1,141-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05023993, a NA study of Malignant Solid Neoplasm and PreDiabetes, is active but no longer recruiting, sponsored by City of Hope Medical Center.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This trial studies the effect of exercise and nicotinamide riboside on muscle health and insulin resistance in adult survivors of childhood cancer with prediabetes (elevated blood sugar level that is not high enough to be considered diabetes). Nicotinamide riboside is a dietary supplement which is similar to vitamin B3. Information collected in this study may help the future development of regimens to improve metabolic outcomes such as muscle health and insulin resistance (when the body is not normally responding to insulin) in childhood cancer survivors.
Primary Outcome
The current protocol will be considered feasible if: 1. \>= 50% of eligible patients that are approached for participation enroll onto the study, 2. \>= 70% of enrolled participants successfully complete all study assessments (i.e. physical function tests, blood draw, imaging, and questionnaires at baseline and 6 weeks, and 3. Enrolled participants demonstrate \>= 70% compliance with prescribed exercise and nicotinamide riboside. Feasibility measures 2 and 3 will be assessed for the entire gro
Conditions Studied
Interventions
- OTHER Exercise Intervention
- DIETARY_SUPPLEMENT Nicotinamide Riboside
Study Locations (1)
California
- City of Hope Medical Center - Duarte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-06-23 |
| Est. Completion | 2026-09-21 |
| Phase | NA |
What the registry record for NCT05023993 still lists
NCT05023993 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,141-participant average among 176 other Malignant Solid Neoplasm trials with a reported enrollment target (98% lower).
The record links to 3 conditions, with Malignant Solid Neoplasm appearing as the primary indexed condition, and to 2 interventions - of which Exercise Intervention is the first listed.
NCT05023993 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05023993 about?
NCT05023993 is a clinical study titled "The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer". This trial studies the effect of exercise and nicotinamide riboside on muscle health and insulin resistance in adult survivors of childhood cancer with prediabetes (elevated blood sugar level that is not high enough to be considered diabetes). Nicotinamide riboside is a dietary supplement which is s...
What is the current status of trial NCT05023993?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2022-06-23. Estimated completion is 2026-09-21.
What conditions does trial NCT05023993 study?
This clinical trial studies the following conditions: Malignant Solid Neoplasm, PreDiabetes, Hematopoietic and Lymphoid Cell Neoplasm.
What interventions are being tested in trial NCT05023993?
The interventions under investigation include: Exercise Intervention (OTHER), Nicotinamide Riboside (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT05023993?
This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05023993 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Malignant Solid Neoplasm
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05023993's enrollment target sits among peer trials
20 161st of 176 higher than 13 of 176 other Malignant Solid Neoplasm trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Malignant Solid Neoplasm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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