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NCT05318183 · ClinicalTrials.gov registry record · NA
Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components
A NA study of PreDiabetes and Inflammation, sponsored by Ohio State University.
- Active
- Registry status
- NA
- Development phase
- 65
- Enrollment target
- 1
- Study location
NCT05318183: Active NA study of PreDiabetes and Inflammation, sponsored by Ohio State University.
NCT05318183 is a NA study of PreDiabetes and Inflammation that is active but no longer recruiting, run by Ohio State University. The registered enrollment target is 65 participants, below the 701-participant average among 149 other PreDiabetes trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05318183, a NA study of PreDiabetes and Inflammation, is active but no longer recruiting, sponsored by Ohio State University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 65 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will investigate the gut microbiota-mediated effects of whole wheat consumption on human health in adults with pre-diabetes. Participants will complete two phases of intervention in random order in which they will consume either whole wheat bread (4 servings) or white bread a day for two weeks prior to collecting specimens (stool, urine, and plasma/serum).
Primary Outcome
Data are biomarker area under the time-concentration curve (0-3 hours) on day 14
Conditions Studied
Interventions
- OTHER Whole Wheat Bread
- OTHER White Bread (control)
Study Locations (1)
Ohio
- The Ohio State University - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 65 participants |
| Start Date | 2022-01-27 |
| Est. Completion | 2026-05-30 |
| Phase | NA |
What the registry record for NCT05318183 still lists
NCT05318183 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 701-participant average among 149 other PreDiabetes trials with a reported enrollment target (91% lower).
The record links to 4 conditions, with PreDiabetes appearing as the primary indexed condition, and to 2 interventions - of which Whole Wheat Bread is the first listed.
NCT05318183 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT05318183 about?
NCT05318183 is a clinical study titled "Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components". This study will investigate the gut microbiota-mediated effects of whole wheat consumption on human health in adults with pre-diabetes. Participants will complete two phases of intervention in random order in which they will consume either whole wheat bread (4 servings) or white bread a day for two ...
What is the current status of trial NCT05318183?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 65 participants. The study started on 2022-01-27. Estimated completion is 2026-05-30.
What conditions does trial NCT05318183 study?
This clinical trial studies the following conditions: PreDiabetes, Inflammation, Dysbiosis, Endotoxemia.
What interventions are being tested in trial NCT05318183?
The interventions under investigation include: Whole Wheat Bread (OTHER), White Bread (control) (OTHER).
Who is sponsoring clinical trial NCT05318183?
This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05318183 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05318183's enrollment target sits among peer trials
65 86th of 149 higher than 63 of 149 other PreDiabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other PreDiabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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