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NCT06976307 · ClinicalTrials.gov registry record · NA
Development of an Inclusive Adaptive Treatment Strategy for Weight Loss in People With Prediabetes Using a Sequential Multiple Assignment Randomized Trial
A NA study of PreDiabetes and Obesity and Overweight, sponsored by University of Alabama at Birmingham.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT06976307 is a NA study of PreDiabetes and Obesity and Overweight that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 30 participants, below the 691-participant average among 89 other PreDiabetes trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06976307, a NA study of PreDiabetes and Obesity and Overweight, is actively recruiting participants, sponsored by University of Alabama at Birmingham.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a sub-study to NCT04745572 to include a new cohort of participants with disabilities. This 16-week study will use an experimental approach called the Sequential Multiple Assignment Randomized Trial to help determine which combination and sequence of weight loss program features are most effective in people who are at risk for type 2 diabetes. Participants in the study will be initially randomized to consume either a high or reduced carbohydrate diet. After 4 weeks, participants will be identified as Responders (greater than or equal to 2.5% weight loss) or Non-Responders (less than 2.5% weight loss). Responders will continue with their initial randomized group for the remainder of the trial. Non-responders will be re-randomized to 2nd stage interventions of either including additional exercise counseling and training or beginning a time restricted eating protocol for the remainder of the trial.
Conditions Studied
Interventions
- BEHAVIORAL High Carbohydrate Diet
- BEHAVIORAL Reduced Carbohydrate Diet
Study Locations (1)
Alabama
- Wellness Health and Research Facility (WHARF) - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2026-03 |
| Est. Completion | 2026-07 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06976307
The ClinicalTrials.gov registry entry for NCT06976307 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 691-participant average among 89 other PreDiabetes trials with a reported enrollment target (96% lower). The listed sponsor is University of Alabama at Birmingham, which has 1,160 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with PreDiabetes appearing as the primary indexed condition, and to 2 interventions - of which High Carbohydrate Diet is the first listed.
NCT06976307 reports 1 study location spanning 1 distinct geographic area - top geographies include Alabama.
Frequently Asked Questions
What is clinical trial NCT06976307 about?
NCT06976307 is a clinical study titled "Development of an Inclusive Adaptive Treatment Strategy for Weight Loss in People With Prediabetes Using a Sequential Multiple Assignment Randomized Trial". This is a sub-study to NCT04745572 to include a new cohort of participants with disabilities. This 16-week study will use an experimental approach called the Sequential Multiple Assignment Randomized Trial to help determine which combination and sequence of weight loss program features are most effe...
What is the current status of trial NCT06976307?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2026-03. Estimated completion is 2026-07.
What conditions does trial NCT06976307 study?
This clinical trial studies the following conditions: PreDiabetes, Obesity and Overweight, Disabilities.
What interventions are being tested in trial NCT06976307?
The interventions under investigation include: High Carbohydrate Diet (BEHAVIORAL), Reduced Carbohydrate Diet (BEHAVIORAL).
Who is sponsoring clinical trial NCT06976307?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06976307 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.