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ClinicalTrials.gov 135 recruiting now official registry

Parkinson Disease clinical trials

135 of 298 indexed Parkinson Disease trials are currently recruiting.

298 US clinical trials · 135 currently recruiting

Parkinson Disease is the subject of 298 registered US clinical trials on ClinicalTrials.gov, 135 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 66 in Phase 1-2 (earlier-stage). The most active sponsor is University of Minnesota, running 10 of these trials.

The research picture

Parkinson Disease has 298 registered US clinical trials, 135 of them open to new participants right now, about 45% of the total.

135
recruiting participants now
45%
of trials open to enrollment
21
in Phase 3–4 (later-stage)
10
top sponsor: University of Minnesota
Phase 131Phase 235Phase 38Phase 413

Active & Recent Trials

298 total, page 1 of 6

RECRUITING 1,000,000 participants

Parkinson's Foundation Surveys

Parkinson's Foundation

NCT05066763

RECRUITING 500,000 participants

Parkinson Progression Marker Initiative Online (PPMI Online)

Michael J. Fox Foundation for Parkinson's Research

NCT05065060

RECRUITING 10,000 participants

Longitudinal Cognitive Assessment by BoCA

Alzheimer's Light

NCT04114994

RECRUITING 5,000 participants

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

Boston Scientific Corporation

NCT03664609

RECRUITING 4,500 participants

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

Michael J. Fox Foundation for Parkinson's Research

NCT04477785

RECRUITING 2,000 participants

Pacific Northwest Udall Center (PANUC) Clinical Core

University of Washington

NCT01720810

RECRUITING 2,000 participants

Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

Michael J. Fox Foundation for Parkinson's Research

NCT06719583

RECRUITING 1,000 participants

University of Delaware Parkinson's Disease Registry

University of Delaware

NCT04496973

RECRUITING 1,000 participants

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

Abbott Medical Devices

NCT04071847

RECRUITING 1,000 participants

Clinical Outcomes for Deep Brain Stimulation

Washington University School of Medicine

NCT03992625

RECRUITING NA 1,000 participants

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

University of Pennsylvania

NCT06377033

RECRUITING NA 1,000 participants

Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

Massachusetts Eye and Ear Infirmary

NCT05317390

RECRUITING 800 participants

Natural History Study of Synucleinopathies

NYU Langone Health

NCT01799915

RECRUITING Phase 2 550 participants

A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease

Biohaven Therapeutics

NCT06976268

RECRUITING 500 participants

North American Prodromal Synucleinopathy Consortium Stage 2

Washington University School of Medicine

NCT05826457

RECRUITING 500 participants

Social & QoL Behaviors in Parkinson's Disease

Gregory Wallace

NCT06385184

RECRUITING NA 370 participants

Study in Parkinson Disease of Exercise

Northwestern University

NCT04284436

RECRUITING Phase 3 330 participants

To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications

Cerevance

NCT06553027

RECRUITING NA 300 participants

Evaluation of Correlation Between Oculometric Measures and Clinical Assessment in Parkinson's Disease

NeuraLight

NCT05862649

RECRUITING 250 participants

C-STAR Movement Database

Shirley Ryan AbilityLab

NCT05471375

RECRUITING 250 participants

Parkinson's Disease and Movement Disorders Clinical Database

University of Pennsylvania

NCT04997642

RECRUITING Phase 4 220 participants

A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease

Impax Laboratories

NCT06765668

RECRUITING Phase 1 205 participants

The University of Alabama At Birmingham (UAB) Neuroinflammation in Parkinson's Disease-TSPO- Positron Emission Tomography (PET) Substudy

University of Alabama at Birmingham

NCT03457493

RECRUITING NA 200 participants

Genetics and Aerobic Exercise to Slow Parkinson's Disease Trial

Jay Alberts

NCT06442033

RECRUITING NA 200 participants

Cerebellar Stimulation and Cognitive Control

Krystal Parker, PhD

NCT03217110

RECRUITING NA 200 participants

Remote Therapeutic Monitoring Exercise Tracking

Shirley Ryan AbilityLab

NCT06306768

RECRUITING NA 150 participants

Rock Steady Boxing: A Community Based In Person Class

University of St. Augustine for Health Sciences

NCT05773612

RECRUITING Phase 2 150 participants

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Neuron23

NCT06680830

RECRUITING NA 140 participants

Investigating Inhibitory Control Networks in Parkinson's Disease

University of Alabama at Birmingham

NCT04735458

RECRUITING NA 136 participants

Modification of Threat Interpretation Bias to Reduce Anxiety in Neurodegenerative Movement Disorders (Aim 3)

University of Virginia

NCT07213648

RECRUITING Phase 2 132 participants

Lenrispodun as Adjunctive Therapy in the Treatment of Patients With Motor Fluctuations Due to Parkinson's Disease

Intra-Cellular Therapies

NCT05766813

RECRUITING Phase 1 127 participants

A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease

Eli Lilly and Company

NCT06809400

RECRUITING Phase 2 127 participants

A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)

AskBio

NCT06285643

RECRUITING NA 123 participants

Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease

VA Office of Research and Development

NCT06088355

RECRUITING Phase 2 120 participants

Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease

Purdue University

NCT06638944

RECRUITING NA 120 participants

Motor Network Physiology

University of Texas Southwestern Medical Center

NCT04957095

RECRUITING 120 participants

Pathways Mediating Impaired Postural Control in Parkinson's Disease

University of Minnesota

NCT06464029

RECRUITING Phase 2 120 participants

Rehabilitation of Airway Protection in Parkinson's Disease

Teachers College, Columbia University

NCT05700825

RECRUITING 120 participants

Home-Based Monitoring in Parkinson's Disease

Jacob E. Simmering

NCT06573762

RECRUITING NA 120 participants

Slow Wave Sleep As a Biomarker of Rehabilitation-induced Cognitive Improvement in PD

University of Colorado, Denver

NCT04796506

RECRUITING 120 participants

Real-World Patient Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States:

Supernus Pharmaceuticals

NCT07219927

RECRUITING 120 participants

Autoimmune Features of Neurodegenerative Disorders

Columbia University

NCT04239079

RECRUITING Phase 2 102 participants

Reducing Falls With Varenicline in Hypocholinergic Parkinson Disease

Vikas Kotagal

NCT06679374

RECRUITING 100 participants

Microbiome Composition and Function Contributes to Cognitive Impairment and Neuroinflammation in Parkinson's Disease

California State University, San Bernardino

NCT05419453

RECRUITING 100 participants

Intestinal Immunity in Neurologic Disease

Yale University

NCT06329453

RECRUITING NA 100 participants

Online Motor Control in People With Parkinson's Disease

University of Delaware

NCT04616508

RECRUITING NA 90 participants

Exercise Neuroprotection in Parkinson's Disease

University of Nevada, Las Vegas

NCT05854524

RECRUITING 90 participants

Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging

University of Texas Southwestern Medical Center

NCT03872102

RECRUITING NA 80 participants

Balance Tele-Rehab in Parkinson's Disease Parkinson's Disease

Oregon Health and Science University

NCT05680597

RECRUITING Phase 4 80 participants

Cortical Electrophysiology of Response Inhibition in Parkinson's Disease

Emory University

NCT06234995

Page 1 of 6 Next →

Reading the Parkinson Disease Trial Landscape

298 indexed Parkinson Disease studies · 135 recruiting (45%).

Phase mix: 21 late (III/IV) vs 66 early (I/II).

Top sponsor: University of Minnesota (10 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Parkinson Disease?

PlainTrial tracks 298 US clinical trials for Parkinson Disease, of which 135 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Parkinson Disease?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.