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Parkinson Disease: early-phase trial registry
135 of 298 indexed Parkinson Disease trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #31 of 28,707 conditions by registered trial count.
298 US clinical trials · 135 currently recruiting · #31 of 28,707 conditions by registered trial count
Parkinson Disease: 298 US clinical trials tracked, 135 recruiting.
Parkinson Disease is the subject of 298 registered US clinical trials on ClinicalTrials.gov, 135 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 66 in Phase 1-2 (earlier-stage). The most active sponsor is University of Minnesota, running 10 of these trials.
Enrollment posture brief
Registry condition parkinson-disease
OPEN 135 | RECR 45% | LATE 21 | EARLY 66 | RANK #31 | SPON 10
Volume-matched condition peers
Nearest open-share peer: Gastric Cancer (45% recruiting · 159 trials)
Parkinson Disease lists 135 open slots (45% of 298 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Parkinson Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Parkinson Disease is recruiting above its size-band peers.
135 of 298 indexed trials (45.3%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Parkinson Disease trials is spread across many organizations.
University of Minnesota accounts for 10 of 298 trials (3.4%). 165 distinct sponsors appear on at least one study for this condition label.
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Most Parkinson Disease trials plan to enrol fewer than 100 people.
Median target enrolment is 55 among the 298 trials that report a genuine target (sentinel values excluded). 207 of those (69.5%) plan for fewer than 100 participants.
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Parkinson Disease research is mostly interventional.
226 interventional and 72 observational studies make up this index (75.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
298 total, page 1 of 6
Parkinson's Foundation Surveys
Parkinson's Foundation
NCT05066763
Parkinson Progression Marker Initiative Online (PPMI Online)
Michael J. Fox Foundation for Parkinson's Research
NCT05065060
Longitudinal Cognitive Assessment by BoCA
Alzheimer's Light
NCT04114994
Deep Brain Stimulation (DBS) Retrospective Outcomes Study
Boston Scientific Corporation
NCT03664609
PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort
Michael J. Fox Foundation for Parkinson's Research
NCT04477785
Pacific Northwest Udall Center (PANUC) Clinical Core
University of Washington
NCT01720810
Black and African Americans Connections to Parkinson's Disease (BLAAC PD)
Michael J. Fox Foundation for Parkinson's Research
NCT06719583
University of Delaware Parkinson's Disease Registry
University of Delaware
NCT04496973
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
Abbott Medical Devices
NCT04071847
Clinical Outcomes for Deep Brain Stimulation
Washington University School of Medicine
NCT03992625
Using the EHR to Advance Genomic Medicine Across a Diverse Health System
University of Pennsylvania
NCT06377033
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
Massachusetts Eye and Ear Infirmary
NCT05317390
Natural History Study of Synucleinopathies
NYU Langone Health
NCT01799915
A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease
Biohaven Therapeutics
NCT06976268
North American Prodromal Synucleinopathy Consortium Stage 2
Washington University School of Medicine
NCT05826457
Social & QoL Behaviors in Parkinson's Disease
Gregory Wallace
NCT06385184
Study in Parkinson Disease of Exercise
Northwestern University
NCT04284436
To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications
Cerevance
NCT06553027
Evaluation of Correlation Between Oculometric Measures and Clinical Assessment in Parkinson's Disease
NeuraLight
NCT05862649
C-STAR Movement Database
Shirley Ryan AbilityLab
NCT05471375
Parkinson's Disease and Movement Disorders Clinical Database
University of Pennsylvania
NCT04997642
A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease
Impax Laboratories
NCT06765668
The University of Alabama At Birmingham (UAB) Neuroinflammation in Parkinson's Disease-TSPO- Positron Emission Tomography (PET) Substudy
University of Alabama at Birmingham
NCT03457493
Genetics and Aerobic Exercise to Slow Parkinson's Disease Trial
Jay Alberts
NCT06442033
Cerebellar Stimulation and Cognitive Control
Krystal Parker, PhD
NCT03217110
Remote Therapeutic Monitoring Exercise Tracking
Shirley Ryan AbilityLab
NCT06306768
Rock Steady Boxing: A Community Based In Person Class
University of St. Augustine for Health Sciences
NCT05773612
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
Neuron23
NCT06680830
Investigating Inhibitory Control Networks in Parkinson's Disease
University of Alabama at Birmingham
NCT04735458
Modification of Threat Interpretation Bias to Reduce Anxiety in Neurodegenerative Movement Disorders (Aim 3)
University of Virginia
NCT07213648
Lenrispodun as Adjunctive Therapy in the Treatment of Patients With Motor Fluctuations Due to Parkinson's Disease
Intra-Cellular Therapies
NCT05766813
A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease
Eli Lilly and Company
NCT06809400
A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)
AskBio
NCT06285643
Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease
VA Office of Research and Development
NCT06088355
Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease
Purdue University
NCT06638944
Motor Network Physiology
University of Texas Southwestern Medical Center
NCT04957095
Pathways Mediating Impaired Postural Control in Parkinson's Disease
University of Minnesota
NCT06464029
Rehabilitation of Airway Protection in Parkinson's Disease
Teachers College, Columbia University
NCT05700825
Home-Based Monitoring in Parkinson's Disease
Jacob E. Simmering
NCT06573762
Slow Wave Sleep As a Biomarker of Rehabilitation-induced Cognitive Improvement in PD
University of Colorado, Denver
NCT04796506
Real-World Patient Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States:
Supernus Pharmaceuticals
NCT07219927
Autoimmune Features of Neurodegenerative Disorders
Columbia University
NCT04239079
Reducing Falls With Varenicline in Hypocholinergic Parkinson Disease
Vikas Kotagal
NCT06679374
Microbiome Composition and Function Contributes to Cognitive Impairment and Neuroinflammation in Parkinson's Disease
California State University, San Bernardino
NCT05419453
Intestinal Immunity in Neurologic Disease
Yale University
NCT06329453
Online Motor Control in People With Parkinson's Disease
University of Delaware
NCT04616508
Exercise Neuroprotection in Parkinson's Disease
University of Nevada, Las Vegas
NCT05854524
Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging
University of Texas Southwestern Medical Center
NCT03872102
Balance Tele-Rehab in Parkinson's Disease Parkinson's Disease
Oregon Health and Science University
NCT05680597
Cortical Electrophysiology of Response Inhibition in Parkinson's Disease
Emory University
NCT06234995
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 31 |
| Phase 2 | 35 |
| Phase 3 | 8 |
| Phase 4 | 13 |
Top Sponsors
Named interventions
Most-linked intervention names on Parkinson Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Parkinson Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Parkinson Disease page
298 registered trials, 135 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 135 Parkinson Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Minnesota sponsors the most Parkinson Disease trials on record, review their full trial history before evaluating a specific study. See University of Minnesota's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Parkinson Disease condition card totals 298 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.