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NCT05854524 · ClinicalTrials.gov registry record · NA
Exercise Neuroprotection in Parkinson's Disease
A NA study of Parkinson Disease, sponsored by University of Nevada, Las Vegas.
- Recruiting
- Registry status
- NA
- Development phase
- 90
- Enrollment target
- 1
- Study location
NCT05854524: Recruiting NA study of Parkinson Disease, sponsored by University of Nevada, Las Vegas.
NCT05854524 is a NA study of Parkinson Disease that is actively recruiting participants, run by University of Nevada, Las Vegas. The registered enrollment target is 90 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05854524, a NA study of Parkinson Disease, is actively recruiting participants, sponsored by University of Nevada, Las Vegas.
- RECRUITING
- Registry status
- NA
- Development phase
- 90 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to explore the relationships of exercise on inflammation in the body of older adults and people with Parkinson's disease (PD). This is important research for older adults but is especially important for people with PD because neuroinflammation is the main pathological mechanism that is responsible for neuron cell death in this neurodegenerative disease. As PD is a progressive disease, halting or slowing the degeneration is an important research target. Halting or slowing the disease progress is known as neuroprotection. Exercise is an attractive therapeutic treatment for people with PD as it has a lot of multi-systemic benefits, but also there is a lot of evidence to suggest that it helps improve symptoms and slow the progression of the disease. Exercise has been theorized to decrease inflammation and, therefore, has a lot of promise as a neuroprotective agent in slowing or halting the degeneration in PD. Unfortunately, there is not a lot of research that has looked into the effect of exercise on the biological processes of inflammation. Thus, the purpose of this study is to investigate the biological evidence that underlies the positive effect of exercise in people with PD.
Primary Outcome
International Physical Activity Questionnaire (IPAQ) and blood serum levels of the following: interleukin-6 (IL-6), tumor necrosis factor alpha (TNF), interleukin-1β (IL-1β), interleukin-2 (IL-2), interleukin-10 (IL-10), c-reactive protein (CRP), RANTES, BDNF, VEGF, nerve growth factor (NGF), GDNF, Superoxide dismutase, catalase, glutathione peroxidase, total antioxidant capacity
Conditions Studied
Interventions
- PROCEDURE Aerobic exercise
Study Locations (1)
Nevada
- Gait and Balance Laboratory, 217 Bigelow Health Sciences Building, UNLV - Las Vegas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2024-08-29 |
| Est. Completion | 2026-12-30 |
| Phase | NA |
What NCT05854524 shows while recruiting
NCT05854524 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Parkinson Disease appearing as the primary indexed condition, and to 1 intervention - of which Aerobic exercise is the first listed.
NCT05854524 reports a single indexed study location in Nevada.
Frequently Asked Questions
What is clinical trial NCT05854524 about?
NCT05854524 is a clinical study titled "Exercise Neuroprotection in Parkinson's Disease". The purpose of this study is to explore the relationships of exercise on inflammation in the body of older adults and people with Parkinson's disease (PD). This is important research for older adults but is especially important for people with PD because neuroinflammation is the main pathological me...
What is the current status of trial NCT05854524?
This trial is currently recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2024-08-29. Estimated completion is 2026-12-30.
What conditions does trial NCT05854524 study?
This clinical trial studies the following conditions: Parkinson Disease.
What interventions are being tested in trial NCT05854524?
The interventions under investigation include: Aerobic exercise (PROCEDURE).
Who is sponsoring clinical trial NCT05854524?
This trial is sponsored by University of Nevada, Las Vegas, which has 52 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05854524 being conducted?
This trial has 1 study location across Nevada. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05854524's enrollment target sits among peer trials
90 97th of 297 higher than 199 of 297 other Parkinson Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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