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NCT04735458 · ClinicalTrials.gov registry record · NA
Investigating Inhibitory Control Networks in Parkinson's Disease
A NA study of Parkinson Disease, sponsored by University of Alabama at Birmingham.
- Recruiting
- Registry status
- NA
- Development phase
- 140
- Enrollment target
- 1
- Study location
NCT04735458: Recruiting NA study of Parkinson Disease, sponsored by University of Alabama at Birmingham.
NCT04735458 is a NA study of Parkinson Disease that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 140 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04735458, a NA study of Parkinson Disease, is actively recruiting participants, sponsored by University of Alabama at Birmingham.
- RECRUITING
- Registry status
- NA
- Development phase
- 140 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate the brain activity associated with non-motor symptoms of movement disorders, including Parkinson's disease and essential tremor. These movement disorders commonly have significant non-motor features also, including depression, cognitive impairment, decreased attention, and slower processing speeds. The investigators are interested in the brain activity associated with these symptoms, and perform recordings of the surface of the brain, in addition to the typical recordings the investigators perform, during routine deep brain stimulation (DBS) surgery.
Primary Outcome
In the Simon task, participants are instructed to respond with a right or left button press (Right = Red, Left = Blue) according to how a word is printed on a screen ("RED" or "BLUE"), regardless of the color in which the word is printed. This is a measurement of accuracy (% correct, ranging from 0-100, with higher scores indicating better performance)
Conditions Studied
Interventions
- OTHER Procedure/Surgery: Response Inhibition and Deep Brain Stimulation in Parkinson's disease
Study Locations (1)
Alabama
- University of Alabama at Birmingham - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 140 participants |
| Start Date | 2021-04-01 |
| Est. Completion | 2028-03-31 |
| Phase | NA |
What NCT04735458 shows while recruiting
NCT04735458 is an interventional study that assigns participants to a tested intervention. The registered 140 participants enrollment target is mid-sized for trials with a published cap, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Parkinson Disease appearing as the primary indexed condition, and to 1 intervention - of which Procedure/Surgery: Response Inhibition and Deep Brain Stimulation in Parkinson's disease is the first listed.
NCT04735458 reports a single indexed study location in Alabama.
Frequently Asked Questions
What is clinical trial NCT04735458 about?
NCT04735458 is a clinical study titled "Investigating Inhibitory Control Networks in Parkinson's Disease". The purpose of this study is to investigate the brain activity associated with non-motor symptoms of movement disorders, including Parkinson's disease and essential tremor. These movement disorders commonly have significant non-motor features also, including depression, cognitive impairment, decreas...
What is the current status of trial NCT04735458?
This trial is currently recruiting. It is a NA study. The enrollment target is 140 participants. The study started on 2021-04-01. Estimated completion is 2028-03-31.
What conditions does trial NCT04735458 study?
This clinical trial studies the following conditions: Parkinson Disease.
What interventions are being tested in trial NCT04735458?
The interventions under investigation include: Procedure/Surgery: Response Inhibition and Deep Brain Stimulation in Parkinson's disease (OTHER).
Who is sponsoring clinical trial NCT04735458?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04735458 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Parkinson Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04735458's enrollment target sits among peer trials
140 57th of 297 higher than 239 of 297 other Parkinson Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinson Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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