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ClinicalTrials.gov 101 recruiting now official registry

Pancreatic Cancer clinical trials

101 of 283 indexed Pancreatic Cancer trials are currently recruiting.

283 US clinical trials · 101 currently recruiting

Pancreatic Cancer is the subject of 283 registered US clinical trials on ClinicalTrials.gov, 101 of them currently open to new participants. 12 are in Phase 3-4 (later-stage) and 180 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 19 of these trials.

The research picture

Pancreatic Cancer has 283 registered US clinical trials, 101 of them open to new participants right now, about 36% of the total.

101
recruiting participants now
36%
of trials open to enrollment
12
in Phase 3–4 (later-stage)
19
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 1114Phase 266Phase 310Phase 42

Active & Recent Trials

283 total, page 3 of 6

RECRUITING Phase 2 10 participants

Chemo4METPANC Combination Chemokine Inhibitor, Immunotherapy, and Chemotherapy in Pancreatic Adenocarcinoma

Gulam Manji

NCT04543071

ACTIVE NOT RECRUITING 6,000 participants

Collection of Tissue & Blood From Patients w/ Benign & Malignant Tumors of the Soft Tissue & Gastrointestinal Tract

Memorial Sloan Kettering Cancer Center

NCT00582647

ACTIVE NOT RECRUITING 1,000 participants

Tempus Priority Study: A Pan-tumor Observational Study

Tempus AI

NCT05179824

ACTIVE NOT RECRUITING Phase 1 702 participants

Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

AstraZeneca

NCT04644068

ACTIVE NOT RECRUITING Phase 2 534 participants

Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)

Hoffmann-La Roche

NCT02568267

ACTIVE NOT RECRUITING Phase 3 501 participants

Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

Revolution Medicines

NCT06625320

ACTIVE NOT RECRUITING 500 participants

Florida Pancreas Collaborative Next Generation Biobank

H. Lee Moffitt Cancer Center and Research Institute

NCT03851133

ACTIVE NOT RECRUITING Phase 1 466 participants

Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid Tumors

Nuvation Bio

NCT06334432

ACTIVE NOT RECRUITING Phase 2 393 participants

A Study of Zolbetuximab (IMAB362) in Adults With Pancreatic Cancer

Astellas Pharma Global Development

NCT03816163

ACTIVE NOT RECRUITING Phase 3 358 participants

Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer

Alliance for Clinical Trials in Oncology

NCT04340141

ACTIVE NOT RECRUITING Phase 2 350 participants

9-ING-41 in Patients with Advanced Cancers

Actuate Therapeutics

NCT03678883

ACTIVE NOT RECRUITING Phase 2 328 participants

Combination Immunotherapy Plus Standard-of-Care Chemotherapy Versus Standard-of-Care Chemotherapy for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer

ImmunityBio

NCT04390399

ACTIVE NOT RECRUITING NA 300 participants

Supportive Oncology Care At Home RCT

Massachusetts General Hospital

NCT04544046

ACTIVE NOT RECRUITING 271 participants

Systematic Hereditary Pancreatic Cancer Risk Assessment and Implications for Personalized Therapy

Dana-Farber Cancer Institute

NCT03060720

ACTIVE NOT RECRUITING NA 205 participants

Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention

M.D. Anderson Cancer Center

NCT05677048

ACTIVE NOT RECRUITING Phase 2 194 participants

Phase 2 Study of TTX-030 and Chemotherapy With or Without Budigalimab for 1L mPDAC Patients

Trishula Therapeutics

NCT06119217

ACTIVE NOT RECRUITING Phase 1 180 participants

P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors

Poseida Therapeutics

NCT05239143

ACTIVE NOT RECRUITING Phase 2 168 participants

Losartan and Nivolumab in Combination With FOLFIRINOX and SBRT in Localized Pancreatic Cancer

Massachusetts General Hospital

NCT03563248

ACTIVE NOT RECRUITING Phase 1 160 participants

A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Participants With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression

A2 Biotherapeutics

NCT05736731

ACTIVE NOT RECRUITING NA 152 participants

PancFit: Multimodal Exercise During Preoperative Therapy for Pancreatic Cancer

M.D. Anderson Cancer Center

NCT03187951

ACTIVE NOT RECRUITING Phase 1 150 participants

A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors

Suzhou Transcenta Therapeutics Co.

NCT04396821

ACTIVE NOT RECRUITING Phase 1 137 participants

ENB003 Plus Pembrolizumab Phase 1b/2a in Solid Tumors

ENB Therapeutics

NCT04205227

ACTIVE NOT RECRUITING NA 133 participants

Stereotactic MRI-guided On-table Adaptive Radiation Therapy (SMART) for Locally Advanced Pancreatic Cancer

Viewray

NCT03621644

ACTIVE NOT RECRUITING Phase 1 130 participants

Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors

NGM Biopharmaceuticals

NCT05215574

ACTIVE NOT RECRUITING NA 110 participants

Study Of Gemcitabine, Nab-paclitaxel, PEGPH20 and Rivaroxaban for Advanced Pancreatic Adenocarcinoma

Memorial Sloan Kettering Cancer Center

NCT02921022

ACTIVE NOT RECRUITING Phase 1 110 participants

Claudin18.2 CAR-T (CT041) in Patients with Gastric, Pancreatic Cancer, or Other Specified Digestive Cancers

CARsgen Therapeutics Co.

NCT04404595

ACTIVE NOT RECRUITING NA 107 participants

RCT of Mobile Apps & FitBit v. Usual Care

Weill Medical College of Cornell University

NCT03623464

ACTIVE NOT RECRUITING 103 participants

A Study of Photon and Proton Chemoradiotherapy as Definitive or Neoadjuvant Therapy in Non-Metastatic Pancreatic Cancer

Mayo Clinic

NCT03902600

ACTIVE NOT RECRUITING 100 participants

Pancreatic Cancer Early Detection Program

White Plains Hospital

NCT02206360

ACTIVE NOT RECRUITING Phase 1 98 participants

A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Sensei Biotherapeutics

NCT05864144

ACTIVE NOT RECRUITING NA 95 participants

Exercise and Nutrition to Improve Pancreatic Cancer Outcomes

University of Oklahoma

NCT03256201

ACTIVE NOT RECRUITING Phase 2 84 participants

Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer

Massachusetts General Hospital

NCT03104439

ACTIVE NOT RECRUITING NA 80 participants

Support Through Remote Observation and Nutrition Guidance (STRONG) Program for Pancreatic Cancer Patients

H. Lee Moffitt Cancer Center and Research Institute

NCT05675059

ACTIVE NOT RECRUITING Phase 1 76 participants

XB2001 in Combination With ONIVYDE + 5-FU/LV (+Folinic Acid) in Advanced Pancreatic Cancer

XBiotech

NCT04825288

ACTIVE NOT RECRUITING Phase 2 76 participants

Platform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pancreas

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT02451982

ACTIVE NOT RECRUITING 74 participants

Predicting Effective Therapy in Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT03033927

ACTIVE NOT RECRUITING Phase 2 71 participants

Boost GVAX Pancreas Vaccine With or Without CY in Patients With Pancreas Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT01088789

ACTIVE NOT RECRUITING Phase 1 71 participants

Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors

NGM Biopharmaceuticals

NCT05311618

ACTIVE NOT RECRUITING Phase 3 58 participants

Tele-PancFit: A Multi-site Trial of Video-based Strengthening Exercise Prehabilitation for Patients With Resectable Pancreatic Cancer

M.D. Anderson Cancer Center

NCT05836870

ACTIVE NOT RECRUITING Phase 1 56 participants

Claudin 18.2-Targeted Chimeric Antigen Receptor T-cells in Subjects With Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma

Legend Biotech USA

NCT05539430

ACTIVE NOT RECRUITING 55 participants

A Study of the Life Changes Experienced by Patients With Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT04427761

ACTIVE NOT RECRUITING Phase 2 53 participants

Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors

Taiho Oncology

NCT05945823

ACTIVE NOT RECRUITING NA 50 participants

Early Supportive Care and Nutritional Support in Adults With Pancreatic Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT05438927

ACTIVE NOT RECRUITING Phase 2 47 participants

Use of High-dose Radiation Therapy Plus Chemotherapy to Improve the Likelihood of Surgical Treatment in Patients With Locally Advanced Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT03523312

ACTIVE NOT RECRUITING Phase 1 42 participants

A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations

HUYABIO International

NCT05163028

ACTIVE NOT RECRUITING NA 40 participants

The MONITOR Study: Remote Monitoring Of a Nutrition Intervention To Optimize Treatment Response

H. Lee Moffitt Cancer Center and Research Institute

NCT06050395

ACTIVE NOT RECRUITING Phase 2 32 participants

Niraparib in Patients With Pancreatic Cancer

Dana-Farber Cancer Institute

NCT03601923

ACTIVE NOT RECRUITING NA 32 participants

Using an End-of-life Conversation Game to Engage Patients With Cancer in Advance Care Planning: Phase 2

Milton S. Hershey Medical Center

NCT06384417

ACTIVE NOT RECRUITING Phase 2 30 participants

Nivolumab + Ipilimumab + Radiation in MSS Pancreatic Cancer

Massachusetts General Hospital

NCT04361162

ACTIVE NOT RECRUITING Phase 2 30 participants

Atezolizumab + Cabozantinib in Patients w/ Metastatic, Refractory Pancreatic Cancer

University of Arizona

NCT04820179

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Phase Distribution

PhaseTrial count
Phase 1 114
Phase 2 66
Phase 3 10
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pancreatic Cancer Trial Landscape

283 indexed Pancreatic Cancer studies · 101 recruiting (36%).

Phase mix: 12 late (III/IV) vs 180 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (19 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pancreatic Cancer?

PlainTrial tracks 283 US clinical trials for Pancreatic Cancer, of which 101 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pancreatic Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.