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ClinicalTrials.gov 101 recruiting now early-phase tilt #33 of 28,707 conditions

Pancreatic Cancer: early-phase trial registry

101 of 283 indexed Pancreatic Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #33 of 28,707 conditions by registered trial count.

283 US clinical trials · 101 currently recruiting · #33 of 28,707 conditions by registered trial count

Pancreatic Cancer: 283 US clinical trials tracked, 101 recruiting.

Pancreatic Cancer is the subject of 283 registered US clinical trials on ClinicalTrials.gov, 101 of them currently open to new participants. 12 are in Phase 3-4 (later-stage) and 180 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 19 of these trials.

Enrollment posture brief

Registry condition pancreatic-cancer

OPEN 101 | RECR 36% | LATE 12 | EARLY 180 | RANK #33 | SPON 19

Nearest open-share peer: Acute Respiratory Failure (36% recruiting · 14 trials)

Major Depressive Disorder38.5%Pancreatic Cancer (this)36%Melanoma33.1%Healthy Volunteers27.8%Leukemia18.6%
Open-enrollment share among volume-matched conditions near Pancreatic Cancer

Pancreatic Cancer lists 101 open slots (36% of 283 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Pancreatic Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Pancreatic Cancer recruits in line with its size-band peers.

    101 of 283 indexed trials (35.7%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Pancreatic Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 19 of 283 trials (6.7%). 165 distinct sponsors appear on at least one study for this condition label.

  3. Most Pancreatic Cancer trials plan to enrol fewer than 100 people.

    Median target enrolment is 60 among the 279 trials that report a genuine target (sentinel values excluded). 170 of those (60.9%) plan for fewer than 100 participants.

  4. Pancreatic Cancer research is mostly interventional.

    237 interventional and 46 observational studies make up this index (83.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1114Phase 266Phase 310Phase 42

Open and recent trials

283 total, page 4 of 6

ACTIVE NOT RECRUITING Early Phase 1 30 participants

Imaging Study of 18F-FAC PET Scans to Assess Standard Treatment in People With Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT05141643

ACTIVE NOT RECRUITING Phase 1 29 participants

Study of Personalized Tumor Vaccines (PCVs) and a PD-L1 Blocker in Patients With Pancreatic Cancer That Can be Treated With Surgery

Memorial Sloan Kettering Cancer Center

NCT04161755

ACTIVE NOT RECRUITING Phase 2 29 participants

A Study of Glipizide to Treat High Blood Sugar in People With Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT06168812

ACTIVE NOT RECRUITING Phase 2 28 participants

Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma

Yale University

NCT03991962

ACTIVE NOT RECRUITING Early Phase 1 28 participants

A Feasibility Study of Ketorolac Treatment for Cachexia in Patients With Advanced Pancreatic Ductal Adenocarcinoma

Andrew Hendifar, MD

NCT05336266

ACTIVE NOT RECRUITING Phase 1 27 participants

Pooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected Mismatch Repair Protein (MMR-p) Colorectal and Pancreatic Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT04117087

ACTIVE NOT RECRUITING Phase 2 25 participants

A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer

Lei Zheng

NCT05604560

ACTIVE NOT RECRUITING Phase 2 24 participants

AGEN1423 and Botensilimab w/ or w/o Chemo in PDAC

Bruno Bockorny

NCT05632328

ACTIVE NOT RECRUITING NA 20 participants

Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer

City of Hope Medical Center

NCT02293954

ACTIVE NOT RECRUITING Phase 1 17 participants

Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)

Memorial Sloan Kettering Cancer Center

NCT05642962

ACTIVE NOT RECRUITING Phase 2 17 participants

Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT05014776

ACTIVE NOT RECRUITING Phase 1 16 participants

QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers.

NantBioScience

NCT03552718

ACTIVE NOT RECRUITING Phase 1 13 participants

huCART-meso + VCN-01 in Pancreatic and Ovarian Cancer

University of Pennsylvania

NCT05057715

ACTIVE NOT RECRUITING Phase 2 12 participants

ZN-c3 + Gemcitabine in Pancreatic Cancer

Brandon Huffman, MD

NCT06015659

ACTIVE NOT RECRUITING NA 12 participants

Pulse-low-dose Rate (PLDR) Radiation in Pancreatic Cancer

Fox Chase Cancer Center

NCT04452357

ACTIVE NOT RECRUITING Phase 2 10 participants

An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib

Incyte Corporation

NCT02955940

ACTIVE NOT RECRUITING Phase 1 7 participants

A Study of Armed, Activated T-Cells in Patients With Advanced Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT04137536

ACTIVE NOT RECRUITING Phase 1 6 participants

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

TCR2 Therapeutics

NCT05451849

ACTIVE NOT RECRUITING Phase 1 5 participants

Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma

Washington University School of Medicine

NCT06141031

COMPLETED 3,028 participants

Creation of the BioBank, Early Detection and Discovery Biomarkers

Corewell Health East

NCT00901680

COMPLETED 1,429 participants

PRospective REgistry of Advanced Stage CancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine

Labcorp Corporation of America Holdings

NCT05697198

COMPLETED NA 712 participants

Biospecimens for Identification of Diseases of the Pancreas.

University of Michigan

NCT01392027

COMPLETED Phase 3 569 participants

Gemcitabine With/Out Erlotinib in Unresectable Locally Advanced/Metastatic Pancreatic Cancer

NCIC Clinical Trials Group

NCT00026338

COMPLETED Phase 3 569 participants

OSI-774 (Tarceva) Plus Gemcitabine in Patients With Locally Advanced, Unresectable or Metastatic Pancreatic Cancer.

OSI Pharmaceuticals

NCT00040183

COMPLETED Phase 3 438 participants

Intraoperative Celiac Plexus Neurolysis for Patients With Operable Pancreatic and Periampullary Cancer

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT00806611

COMPLETED NA 431 participants

Trial of Ascertaining Individual Preferences for Loved One's Role in End-of-Life

Johns Hopkins University

NCT01160367

COMPLETED Phase 3 405 participants

Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers

Alliance for Clinical Trials in Oncology

NCT02349412

COMPLETED 386 participants

Clinical Validation of a Blood Biomarker Test to Detect Early-Stage Pancreatic Cancer (VERIFI)

Immunovia

NCT06947395

COMPLETED NA 375 participants

Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer

Wake Forest University Health Sciences

NCT01656044

COMPLETED Phase 1 313 participants

Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers

Five Prime Therapeutics

NCT02526017

COMPLETED NA 301 participants

OPTimizing Treatment Focused Genetic Testing IN Cancer

Dana-Farber Cancer Institute

NCT04066361

COMPLETED Phase 1 269 participants

Study of XB002 in Subjects With Solid Tumors (JEWEL-101)

Exelixis

NCT04925284

COMPLETED NA 261 participants

Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms

University of Pittsburgh

NCT01640522

COMPLETED Phase 1 215 participants

NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

NeoImmuneTech

NCT04332653

COMPLETED Phase 2 205 participants

A Study of AGS-1C4D4 Given in Combination With Gemcitabine in Subjects With Metastatic Pancreatic Cancer

Astellas Pharma

NCT00902291

COMPLETED Phase 1 185 participants

A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands

Novartis Pharmaceuticals

NCT01351103

COMPLETED Phase 1 170 participants

A Study in Metastatic Cancer and Advanced or Metastatic Unresectable Pancreatic Cancer

Eli Lilly and Company

NCT01373164

COMPLETED Phase 1 164 participants

A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors

Eli Lilly and Company

NCT02791334

COMPLETED Phase 1 150 participants

ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study

Ability Pharmaceuticals SL

NCT04431258

COMPLETED NA 140 participants

Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle

Northwestern University

NCT01769248

COMPLETED 130 participants

A Registry of Patients Undergoing Cellvizio Endomicroscopy and Endoscopic Retrograde Cholangiopancreatography(ERCP) Imaging Procedures for Diagnosing Pancreatic and Bile Duct Cancers

Mauna Kea Technologies

NCT00779688

COMPLETED NA 125 participants

Nurse-Provided Care or Standard Care in Treating Patients With Pancreatic Cancer

City of Hope Medical Center

NCT00902733

COMPLETED 115 participants

Visceral Lymphatic Mapping Using Isosulfan Blue in Patients With Cancer of the Pancreas, Colon, Stomach, Small Intestine, or Gallbladder

Wake Forest University Health Sciences

NCT00489515

COMPLETED 112 participants

Prospective Analysis of Hypersensitivity Reactions to Oxaliplatin

Dana-Farber Cancer Institute

NCT00831571

COMPLETED Phase 1 105 participants

A Study of SY 5609, a Selective CDK7 Inhibitor, in Advanced Solid Tumors

Syros Pharmaceuticals

NCT04247126

COMPLETED Phase 4 100 participants

Prospective Study of Celiac Block Injection: 1 vs. 2

Indiana University

NCT00583479

COMPLETED Early Phase 1 100 participants

Fatigue and Pancreas and Bile Duct Cancer Study

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT00902759

COMPLETED NA 90 participants

Slide Interpretation or Standard Surgical Pathology in Assessing Margin Status in Patients With Pancreatic Cancer Undergoing Surgery

Ohio State University Comprehensive Cancer Center

NCT01646697

COMPLETED Phase 2 88 participants

A Phase 2 Study of MM-141 Plus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer

Merrimack Pharmaceuticals

NCT02399137

COMPLETED Phase 2 85 participants

Safety and Exploratory Efficacy of Kanglaite Injection in Pancreatic Cancer

KangLaiTe U

NCT00733850

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Phase Distribution

PhaseTrial count
Phase 1 114
Phase 2 66
Phase 3 10
Phase 4 2

Named interventions

Most-linked intervention names on Pancreatic Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Gemcitabine Drug
20 trials
Cyclophosphamide Drug
10 trials
gemcitabine hydrochloride Drug
7 trials
Nivolumab Drug
6 trials
Pembrolizumab Drug
6 trials
erlotinib hydrochloride Drug
5 trials
Irinotecan Drug
5 trials
Oxaliplatin Drug
5 trials

US sites by state

Facility locations filed on Pancreatic Cancer trials. A trial with sites in several states counts in each.

New York 74 trials
California 72 trials
Florida 67 trials
Texas 62 trials
Massachusetts 43 trials
Maryland 38 trials
Michigan 35 trials
Arizona 32 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Pancreatic Cancer page

283 registered trials, 101 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pancreatic Cancer condition card totals 283 registered trials; most-linked intervention Gemcitabine; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.