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ClinicalTrials.gov 101 recruiting now official registry

Pancreatic Cancer clinical trials

101 of 283 indexed Pancreatic Cancer trials are currently recruiting.

283 US clinical trials · 101 currently recruiting

Pancreatic Cancer is the subject of 283 registered US clinical trials on ClinicalTrials.gov, 101 of them currently open to new participants. 12 are in Phase 3-4 (later-stage) and 180 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 19 of these trials.

The research picture

Pancreatic Cancer has 283 registered US clinical trials, 101 of them open to new participants right now, about 36% of the total.

101
recruiting participants now
36%
of trials open to enrollment
12
in Phase 3–4 (later-stage)
19
top sponsor: Memorial Sloan Kettering Cancer Center
Phase 1114Phase 266Phase 310Phase 42

Active & Recent Trials

283 total, page 4 of 6

ACTIVE NOT RECRUITING Early Phase 1 30 participants

Imaging Study of 18F-FAC PET Scans to Assess Standard Treatment in People With Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT05141643

ACTIVE NOT RECRUITING Phase 1 29 participants

Study of Personalized Tumor Vaccines (PCVs) and a PD-L1 Blocker in Patients With Pancreatic Cancer That Can be Treated With Surgery

Memorial Sloan Kettering Cancer Center

NCT04161755

ACTIVE NOT RECRUITING Phase 2 29 participants

A Study of Glipizide to Treat High Blood Sugar in People With Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT06168812

ACTIVE NOT RECRUITING Phase 2 28 participants

Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma

Yale University

NCT03991962

ACTIVE NOT RECRUITING Early Phase 1 28 participants

A Feasibility Study of Ketorolac Treatment for Cachexia in Patients With Advanced Pancreatic Ductal Adenocarcinoma

Andrew Hendifar, MD

NCT05336266

ACTIVE NOT RECRUITING Phase 1 27 participants

Pooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Resected Mismatch Repair Protein (MMR-p) Colorectal and Pancreatic Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT04117087

ACTIVE NOT RECRUITING Phase 2 25 participants

A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer

Lei Zheng

NCT05604560

ACTIVE NOT RECRUITING Phase 2 24 participants

AGEN1423 and Botensilimab w/ or w/o Chemo in PDAC

Bruno Bockorny

NCT05632328

ACTIVE NOT RECRUITING NA 20 participants

Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer

City of Hope Medical Center

NCT02293954

ACTIVE NOT RECRUITING Phase 1 17 participants

Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)

Memorial Sloan Kettering Cancer Center

NCT05642962

ACTIVE NOT RECRUITING Phase 2 17 participants

Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT05014776

ACTIVE NOT RECRUITING Phase 1 16 participants

QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers.

NantBioScience

NCT03552718

ACTIVE NOT RECRUITING Phase 1 13 participants

huCART-meso + VCN-01 in Pancreatic and Ovarian Cancer

University of Pennsylvania

NCT05057715

ACTIVE NOT RECRUITING Phase 2 12 participants

ZN-c3 + Gemcitabine in Pancreatic Cancer

Brandon Huffman, MD

NCT06015659

ACTIVE NOT RECRUITING NA 12 participants

Pulse-low-dose Rate (PLDR) Radiation in Pancreatic Cancer

Fox Chase Cancer Center

NCT04452357

ACTIVE NOT RECRUITING Phase 2 10 participants

An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib

Incyte Corporation

NCT02955940

ACTIVE NOT RECRUITING Phase 1 7 participants

A Study of Armed, Activated T-Cells in Patients With Advanced Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT04137536

ACTIVE NOT RECRUITING Phase 1 6 participants

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

TCR2 Therapeutics

NCT05451849

ACTIVE NOT RECRUITING Phase 1 5 participants

Radiotherapy in Combination With TTI-101 in Borderline Resectable and Locally Advanced Pancreatic Ductal Adenocarcinoma

Washington University School of Medicine

NCT06141031

COMPLETED 3,028 participants

Creation of the BioBank, Early Detection and Discovery Biomarkers

Corewell Health East

NCT00901680

COMPLETED 1,429 participants

PRospective REgistry of Advanced Stage CancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine

Labcorp Corporation of America Holdings

NCT05697198

COMPLETED NA 712 participants

Biospecimens for Identification of Diseases of the Pancreas.

University of Michigan

NCT01392027

COMPLETED Phase 3 569 participants

Gemcitabine With/Out Erlotinib in Unresectable Locally Advanced/Metastatic Pancreatic Cancer

NCIC Clinical Trials Group

NCT00026338

COMPLETED Phase 3 569 participants

OSI-774 (Tarceva) Plus Gemcitabine in Patients With Locally Advanced, Unresectable or Metastatic Pancreatic Cancer.

OSI Pharmaceuticals

NCT00040183

COMPLETED Phase 3 438 participants

Intraoperative Celiac Plexus Neurolysis for Patients With Operable Pancreatic and Periampullary Cancer

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT00806611

COMPLETED NA 431 participants

Trial of Ascertaining Individual Preferences for Loved One's Role in End-of-Life

Johns Hopkins University

NCT01160367

COMPLETED Phase 3 405 participants

Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers

Alliance for Clinical Trials in Oncology

NCT02349412

COMPLETED 386 participants

Clinical Validation of a Blood Biomarker Test to Detect Early-Stage Pancreatic Cancer (VERIFI)

Immunovia

NCT06947395

COMPLETED NA 375 participants

Negative Pressure Therapy in Preventing Infection After Surgery in Patients With Colon, Rectal, Pancreatic, or Peritoneal Surface Cancer

Wake Forest University Health Sciences

NCT01656044

COMPLETED Phase 1 313 participants

Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers

Five Prime Therapeutics

NCT02526017

COMPLETED NA 301 participants

OPTimizing Treatment Focused Genetic Testing IN Cancer

Dana-Farber Cancer Institute

NCT04066361

COMPLETED Phase 1 269 participants

Study of XB002 in Subjects With Solid Tumors (JEWEL-101)

Exelixis

NCT04925284

COMPLETED NA 261 participants

Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms

University of Pittsburgh

NCT01640522

COMPLETED Phase 1 215 participants

NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

NeoImmuneTech

NCT04332653

COMPLETED Phase 2 205 participants

A Study of AGS-1C4D4 Given in Combination With Gemcitabine in Subjects With Metastatic Pancreatic Cancer

Astellas Pharma

NCT00902291

COMPLETED Phase 1 185 participants

A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands

Novartis Pharmaceuticals

NCT01351103

COMPLETED Phase 1 170 participants

A Study in Metastatic Cancer and Advanced or Metastatic Unresectable Pancreatic Cancer

Eli Lilly and Company

NCT01373164

COMPLETED Phase 1 164 participants

A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors

Eli Lilly and Company

NCT02791334

COMPLETED Phase 1 150 participants

ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study

Ability Pharmaceuticals SL

NCT04431258

COMPLETED NA 140 participants

Prospective Trial of EUS-FNA Versus EUS-FNB Using a Novel Core Biopsy Needle

Northwestern University

NCT01769248

COMPLETED 130 participants

A Registry of Patients Undergoing Cellvizio Endomicroscopy and Endoscopic Retrograde Cholangiopancreatography(ERCP) Imaging Procedures for Diagnosing Pancreatic and Bile Duct Cancers

Mauna Kea Technologies

NCT00779688

COMPLETED NA 125 participants

Nurse-Provided Care or Standard Care in Treating Patients With Pancreatic Cancer

City of Hope Medical Center

NCT00902733

COMPLETED 115 participants

Visceral Lymphatic Mapping Using Isosulfan Blue in Patients With Cancer of the Pancreas, Colon, Stomach, Small Intestine, or Gallbladder

Wake Forest University Health Sciences

NCT00489515

COMPLETED 112 participants

Prospective Analysis of Hypersensitivity Reactions to Oxaliplatin

Dana-Farber Cancer Institute

NCT00831571

COMPLETED Phase 1 105 participants

A Study of SY 5609, a Selective CDK7 Inhibitor, in Advanced Solid Tumors

Syros Pharmaceuticals

NCT04247126

COMPLETED Phase 4 100 participants

Prospective Study of Celiac Block Injection: 1 vs. 2

Indiana University

NCT00583479

COMPLETED Early Phase 1 100 participants

Fatigue and Pancreas and Bile Duct Cancer Study

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

NCT00902759

COMPLETED NA 90 participants

Slide Interpretation or Standard Surgical Pathology in Assessing Margin Status in Patients With Pancreatic Cancer Undergoing Surgery

Ohio State University Comprehensive Cancer Center

NCT01646697

COMPLETED Phase 2 88 participants

A Phase 2 Study of MM-141 Plus Nab-paclitaxel and Gemcitabine in Front-line Metastatic Pancreatic Cancer

Merrimack Pharmaceuticals

NCT02399137

COMPLETED Phase 2 85 participants

Safety and Exploratory Efficacy of Kanglaite Injection in Pancreatic Cancer

KangLaiTe U

NCT00733850

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Phase Distribution

PhaseTrial count
Phase 1 114
Phase 2 66
Phase 3 10
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pancreatic Cancer Trial Landscape

283 indexed Pancreatic Cancer studies · 101 recruiting (36%).

Phase mix: 12 late (III/IV) vs 180 early (I/II).

Top sponsor: Memorial Sloan Kettering Cancer Center (19 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pancreatic Cancer?

PlainTrial tracks 283 US clinical trials for Pancreatic Cancer, of which 101 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pancreatic Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.