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Obesity: early-phase trial registry
306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3 of 28,707 conditions by registered trial count.
1,057 US clinical trials · 306 currently recruiting · #3 of 28,707 conditions by registered trial count
Obesity: 1,057 US clinical trials tracked, 306 recruiting.
Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.
Enrollment posture brief
Registry condition obesity
OPEN 306 | RECR 29% | LATE 107 | EARLY 196 | RANK #3 | SPON 48
Volume-matched condition peers
Nearest open-share peer: Metastatic Pancreatic Adenocarcinoma (29% recruiting · 38 trials)
Obesity lists 306 open slots (29% of 1,057 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Obesity is recruiting below its size-band peers.
306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obesity trials is spread across many organizations.
Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.
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Typical Obesity enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.
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Obesity research is mostly interventional.
894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,057 total, page 14 of 22
Identifying Risk for Diabetes and Heart Disease in Women
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT01809288
Financial Incentives to Exercise for Adolescents
University of Oklahoma
NCT01848353
Colonoscopy in the Prone Position for Patients With BMI Greater Than 30
University of Virginia
NCT03337217
Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Acute Treatment
Yale University
NCT03924193
Effect of Exercise and Surgical Weight Loss on Polyneuropathy
University of Michigan
NCT03617185
Exploring Beliefs and Behaviors About Weight Loss in Couples
Duke University
NCT01777711
Food Environment, Food Insecurity, and Health Behaviors in NH Hispanics
University of New Hampshire
NCT05424367
Incentives Targeting Gestational Weight Gain in Overweight/Obese Low Income Women
University of Vermont
NCT02233673
Long-term Exercise, Weight Loss and Energy Balance
University of Kansas
NCT01186523
Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Acute Treatment
Yale University
NCT03045341
Weight Loss In Obese Subjects Taking Either GW869682 Or Placebo 3 Times Per Day For 12 Weeks
GlaxoSmithKline
NCT00297180
Changes in Body Composition Following Bariatric Surgery
Peter Nau
NCT02148068
Pilot Study of the Effect of Liraglutide 3.0 mg on Weight Loss and Gastric Functions in Obesity
Michael Camilleri, MD
NCT03523273
The Chocolate Study
Oregon Research Institute
NCT01949636
Effect of a Novel Nutraceutical on Weight Loss and Weight Maintenance in Obese Subjects
MetaProteomics
NCT01656681
Prevention of Childhood Obesity
Stanford University
NCT00788203
Physical Activity Following Surgery Induced Weight Loss
University of Pittsburgh
NCT00692367
Trospium Chloride XR in Obese Female Patients With Overactive Bladder
Allergan
NCT00932022
A Study to Measure the Effects of Using Tradipitant on Nausea and Vomiting After GLP-1R Agonist Use
Vanda Pharmaceuticals
NCT06804603
Diets Enriched With Pecans
University of Georgia
NCT04376632
Lifestyle Interventions for Expectant Mothers (LIFE-Moms Phoenix) - Phoenix
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT01812694
Brain Regulation of Appetite in Twins
University of Washington
NCT02483663
Ripple Effect of Lifestyle Intervention During Pregnancy on Partners' Weight
California Polytechnic State University-San Luis Obispo
NCT01770028
Cardiovascular Outcomes Of Diet Counseling
The Camelot Foundation
NCT00324545
Brain Activation in Response to Appetitive Cues Pre- and Post- Bariatric Surgery
New York Obesity and Nutrition Research Center
NCT01590914
A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight
Eli Lilly and Company
NCT06824051
Self-Efficacy in Weight Loss Treatment
Lora Burke
NCT00896194
A Prospective, Multi-center, Single-arm Study of the Stomach, Intestinal and Pylorus Sparing (SIPS) Procedure
Medtronic - MITG
NCT02275208
Oral Glucose Tolerance Testing After Gestational Diabetes
MetroHealth Medical Center
NCT02082301
Role of Cysteinyl Leukotrienes in the Pathogenesis of Asthma in Obesity
University of Michigan
NCT01158573
ADJUnct Semaglutide Treatment in Type 1 Diabetes
Viral N. Shah
NCT05537233
Loss of Grip Strength, BMI, and Adjuvant Endocrine Therapy Breast Cancer
University of Michigan Rogel Cancer Center
NCT01896050
Home Plate: A Trial to Improve Home Food Preparation Practices Among Parents of Toddlers
Children's Hospital of Philadelphia
NCT02458833
A Study of Tirzepatide in Overweight and Very Overweight Participants
Eli Lilly and Company
NCT04311411
Neural Mechanisms for Appetitive Responses to High Reward Foods
University of Southern California
NCT02945475
Decreasing Stress and Improving Self-control With "Stress in Control" (Sync) Training
Yale University
NCT01721499
FitEx for Endometrial Cancer Survivors: Initial Efficacy
Carilion Clinic
NCT05737745
Single and Multiple Ascending Dose Study of AMG 133 in Participants With Obesity
Amgen
NCT04478708
Bitter Taste and Weight Loss in Women
Rutgers University
NCT01856660
Underlying Mechanisms of Obesity-induced Obstructive Sleep Apnea
Brandon Nokes
NCT04793334
FoodRx for Obesity Treatment
University of Pennsylvania
NCT05635019
Behavioral Weight Loss and Stigma Reduction
University of Pennsylvania
NCT03704064
Incentivizing Behavior Change Skills to Promote Weight Loss
Duke University
NCT02691260
The Health Influences of Puberty (HIP) Study
University of Colorado, Denver
NCT01775813
Enhancing Sleep Duration: Effects on Children's Eating and Activity Behaviors
The Miriam Hospital
NCT01508793
Motivating Value of Vegetables Study
USDA Grand Forks Human Nutrition Research Center
NCT02585102
Effects of Omega-3 Fatty Acids on Markers of Inflammation
Stanford University
NCT01129050
Validation of Hand Held Indirect Calorimeter in Overweight and Obese Patients
Milton S. Hershey Medical Center
NCT00670969
A Pilot Weight Control Intervention at HPHC
Dana-Farber Cancer Institute
NCT00644202
Medications With or Without WeightWatchers
Michelle Cardel, PhD, MS, RD
NCT06470659
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 95 |
| Phase 2 | 101 |
| Phase 3 | 69 |
| Phase 4 | 38 |
Top Sponsors
Named interventions
Most-linked intervention names on Obesity records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Obesity trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Obesity page
1,057 registered trials, 306 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 306 Obesity trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eli Lilly and Company sponsors the most Obesity trials on record, review their full trial history before evaluating a specific study. See Eli Lilly and Company's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obesity condition card totals 1,057 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.